3,627 results match your criteria: "Centre for Dentistry[Affiliation]"

: Sjögren's disease (SjD) is an autoimmune disease causing irreversible damage to the exocrine glands but can have symptoms throughout the entire body. The aim of this study is to determine the prevalence of Sjogren's disease (SjD) in the Netherlands, compare this with the prevalence for other countries in a systematic literature review. : In the first part of this study, the prevalence of SjD was determined at two academic dental clinics in the Netherlands by electronically analysing patient records.

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Background: The aim of this study was to explore predictors associated with reasons for visiting an oral healthcare professional (OHP) and satisfaction with OHPs in the Netherlands among the Indian migrants and the host population.

Methods: A random sample was obtained for this cross-sectional questionnaire study. Variables were classified according to the Andersen Behavioural Model of Health Services Utilization.

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Prosthetic rehabilitation of segmental mandibulectomy patient using a free fibula flap and Corticobasal implant supported prosthesis: A Case report.

Int J Surg Case Rep

November 2024

Department of Prosthodontics, RAK College of Dental Sciences, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates. Electronic address:

Introduction: Segmental mandibular reconstruction using free fibula flaps and implants is challenging for maxillofacial surgeons and prosthodontists. This case report describes the successful use of Corticobasal implant reconstructive prostheses after a free fibula flap with five years of follow-up.

Clinical Case Presentation: A 24-year-old female presented to the clinic following segmental defect reconstruction using fibula reconstruction, owing to squamous cell carcinoma resection and seeking prosthetic treatment.

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Psychiatry and sensation: the epigenetic links.

Epigenomics

October 2024

Department of Interdisciplinary Medicine, "Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari Aldo Moro, Bari, 70124, Italy.

Article Synopsis
  • The article explores how sensory, social, and genetic factors interact to influence the development of psychiatric disorders across different age groups.
  • It highlights the connection between sensory deficits—like issues with vision or hearing—and mental health, pointing out that social isolation and cognitive challenges can exacerbate these problems.
  • The importance of addressing social determinants, such as loneliness and chronic stress, is emphasized to improve treatment options for psychiatric conditions by integrating sensory and epigenetic considerations.
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The influence of hydrogen sulfide on gingival wound healing: An in vitro study.

J Periodontal Res

October 2024

Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands.

Flowchart and timeline (in hours) of the in vitro experimental procedures.

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Article Synopsis
  • A smartphone-based ecological momentary assessment (EMA) method was used to collect data on awake bruxism (AB) behaviors from 77 young adults over a six-month period.
  • The study found that most individuals reported a consistent frequency of relaxed jaw muscles, while teeth contact and mandible bracing were the most common AB behaviors observed.
  • The results indicated that AB behaviors showed moderate variability day-to-day, with no significant differences over the study periods and no gender differences, suggesting a stable frequency of AB behaviors among healthy individuals.
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Integration of reconstructed human skin (RhS) into organ-on-chip (OoC) platforms addresses current limitations imposed by static culturing. This innovation, however, is not without challenges. Microfluidic devices, while powerful, often encounter usability, robustness, and gas bubble issues that hinder large-scale high-throughput setups.

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Oral Chronic Graft-versus-Host Disease and Oral Health after Allogeneic Hematopoietic Cell Transplantation - What the Care Team Needs to Know.

Transplant Cell Ther

September 2024

Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, Massachusetts; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts.

Article Synopsis
  • Oral chronic graft-versus-host disease (cGVHD) can lead to various symptoms affecting the mouth, contributing to a lower quality of life for patients.
  • Symptoms can include changes in the oral mucosa, reduced saliva production, and issues with surrounding soft tissues.
  • The review aims to offer a straightforward guide for diagnosing and managing oral health problems in both pediatric and adult patients who have received allogeneic hematopoietic cell transplantation (alloHCT) within the first two years after their procedure.
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Background: Osseointegrated dental implants are widely established as a first-choice treatment for the replacement of missing teeth. Clinical outcomes are however often compromised by short or longer-term biological complications and pathologies. Nanoparticle-coated materials represent a very active research area with the potential to enhance clinical outcomes and reduce complications of implant therapy.

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Temporomandibular disorders: INfORM/IADR key points for good clinical practice based on standard of care.

Cranio

October 2024

International Network for Orofacial Pain and Related Disorders Methodology (INfORM), a Network within the International Association for Dental Research (IADR).

Objective: To present a list of key points for good Temporomandibular Disorders (TMDs) clinical practice on behalf of the International Network for Orofacial Pain and Related Disorders Methodology (INfORM) group of the International Association for Dental, Oral and Craniofacial Research (IADR).

Methods: An open working group discussion was held at the IADR General Session in New Orleans (March 2024), where members of the INfORM group finalized the proposal of a list of 10 key points.

Results: The key points covered knowledge on the etiology, diagnosis, and treatment.

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Oral health of Dutch primary school children in relation to social and health aspects.

Acta Odontol Scand

October 2024

Utrecht University of Applied Sciences, Research Group Innovation in Preventive Healthcare, Utrecht, The Netherlands; Academic Centre for Dentistry Amsterdam (ACTA), Department of Oral Public Health, University of Amsterdam and VU University, Amsterdam, The Netherlands.

Objective: This research investigated the oral health status of Dutch primary school children aged 10-12 years in Utrecht and its association with demographic characteristics, lifestyle factors, general psychosocial health, and dental treatment, to guide targeted interventions to improve children's oral and overall well-being.

Materials And Methods: A cross-sectional survey was conducted at 49 primary schools in Utrecht in 2017 and 42 schools in 2019. The questionnaire covered background characteristics (7 questions), psychosocial health (14 questions), nutrition and exercise (20 questions), school and leisure time (26 questions), home situation (23 questions), and oral health (4 questions).

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Background: Reporting conflicts of interest (COI) and sources of sponsorship are of paramount importance in adequately interpreting the results of systematic reviews. Some evidence suggests that there is an influence of COI and sponsorship on the study results. The objectives of this meta-research study were twofold: (a) to assess the reporting of COI and sponsorship statements in systematic reviews published in dentistry in three sources (abstract, journal's website and article's full text) and (b) to assess the associations between the characteristics of the systematic reviews and reporting of COI.

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Gene-environmental influence of space and microgravity on red blood cells with sickle cell disease.

NPJ Genom Med

September 2024

Dutch Experiment Support Center (DESC), Department of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam Bone Center (ABC), Amsterdam UMC Location VU University Medical Center (VUmc) & Academic Centre for Dentistry Amsterdam (ACTA), Gustav Mahlerlaan 3004, 1081, LA Amsterdam, The Netherlands.

A fundamental question in human biology and for hematological disease is how do complex gene-environment interactions lead to individual disease outcome? This is no less the case for sickle cell disease (SCD), a monogenic disorder of Mendelian inheritance, both clinical course, severity, and treatment response, is variable amongst affected individuals. New insight and discovery often lie between the intersection of seemingly disparate disciplines. Recently, opportunities for space medicine have flourished and have offered a new paradigm for study.

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Article Synopsis
  • Tooth wear is a complex issue that leads to the loss of dental tissue, and the study aimed to evaluate the reliability of the tooth wear evaluation system (TWES) 2.0 when used by dental students as opposed to experienced professionals.
  • The study involved 47 dental students assessing 14 patient cases, and the analysis revealed variable agreement levels among the students, with some areas showing higher reliability than others.
  • The findings suggest that the students struggled more with assessing restorations than natural teeth, especially in specific areas, indicating a need for better training and clearer definitions of tooth wear levels to improve assessment accuracy in future research.
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Background: A variety of firing protocols are available for the IPS e.max lithium disilicate (LD) and can be used for new, 'advanced' LD (ALD). However, the impact of firing protocols on the optical properties of ALD is still unknown.

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Molar Incisor Hypomineralisation as a Dental Caries Risk Factor - Is It True?

Monogr Oral Sci

September 2024

Department of Cariology, Centre for Dentistry and Oral Hygiene, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.

The development of the human dentition is susceptible to disruption owing to its intricate and delicate nature, encompassing variations in tooth number, anatomical configuration, and the characteristics of enamel, dentine, and cementum. This chapter will specifically address the prevalent defect of molar incisor hypomineralisation (MIH), which can impose a significant treatment burden on individuals. MIH is linked to deleterious alterations in the properties of affected enamel, which can lead to rapid enamel breakdown and carious lesion formation in those at a heightened caries risk.

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: Limited research has been performed to assess the strength of resin-bonded 3D-printed restorations. Based on that, this study investigates the impact of different manufacturing methods on the fracture load of indirect composite restorations (ICRs) following an aging process. : Three manufacturing techniques-conventional (CRC), milled (MRC), and printed (PRC)-were evaluated using 60 specimens, each with a diameter of 10 mm and a thickness of 1.

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Article Synopsis
  • The study focused on how doctors use a treatment called intralesional corticosteroid administration (ICA) for keloids, which are raised scars.
  • A group of 23 keloid experts worked together online to agree on the best methods for using this treatment to help improve results.
  • They reached agreements on some practices but didn’t all agree on the exact dosage and other details, highlighting the need for clearer treatment guidelines.
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Multi-way modelling of oral microbial dynamics and host-microbiome interactions during induced gingivitis.

NPJ Biofilms Microbiomes

September 2024

Biosystems Data Analysis, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands.

Gingivitis-the inflammation of the gums-is a reversible stage of periodontal disease. It is caused by dental plaque formation due to poor oral hygiene. However, gingivitis susceptibility involves a complex set of interactions between the oral microbiome, oral metabolome and the host.

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Dental Abnormalities in Osteogenesis Imperfecta: A Systematic Review.

Calcif Tissue Int

November 2024

Amsterdam Reproduction and Development, Amsterdam, The Netherlands.

Article Synopsis
  • - Osteogenesis imperfecta (OI) is a genetic disorder that leads to brittle bones and various dental issues, with a prevalence of dentinogenesis imperfecta (DI) between 20-48% among affected individuals
  • - A systematic review found that people with more severe forms of OI (types III and IV) have more dental abnormalities compared to those with milder forms (type I), while OI type V usually does not exhibit DI
  • - The review also highlights significant variability in malocclusion types in OI patients, with common occurrences of open bites and missing teeth, stressing the importance of thorough dental evaluations and the need for better diagnostic guidelines for DI.
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Salmonellosis is a common foodborne disease caused by bacteria. The emergence of multidrug-resistant (MDR) Salmonella serotypes, such as Typhimurium, and Salmonella's ability to form biofilms contribute to their resistance and persistence in host and non-host environments. New strategies are needed to treat or prevent Salmonella infections.

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Background: Temporomandibular disorders (TMDs) are conditions that involve the temporomandibular joints, masticatory muscles, and associated tissues, causing orofacial pain. Central sensitisation (CS) is a relevant part of the TMD pathophysiology. Migraine, psychological aspects, parafunctional oral habits and widespread pain are commonly associated with both TMD and CS and could confound the association between them.

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