Prosthetic rehabiliatation of a hemimaxillectomy patient using a zygomatic - Corticobasal® implant- supported reconstructive prosthesis: A case report.

Introduction: Rehabilitation of patients with hemimaxillectomy presents a challenge. This case report describes the successful use of zygomatic Corticobasal® implant- supported reconstructed prosthesis.

Clinical Case Presentation: A 20-year-old female patient presented to the clinic following hemimaxillectomy with soft tissue approximation one year ago.

Evaluation and refinement of thresholds for early migration of total knee replacements as an estimator of late aseptic loosening: an updated systematic review of RSA and survival studies.

Background And Purpose:  This study updates 2 parallel systematic reviews and meta-analyses from 2012, which established the 1-year radiostereometric (RSA) migration thresholds for tibial components of total knee replacements (TKR) based on the risk of late revision for aseptic loosening from survival studies. The primary aim of this study was to determine the (mis)categorization rate of the 2012 thresholds using the updated review as a validation dataset. Secondary aims were evaluation of 6-month migration, mean continuous (1- to 2-year) migration, and fixation-specific thresholds for tibial component migration.

Effect of Daily Vitamin C Supplementation with or Without Flavonoids on Periodontal, Microbial, and Systemic Conditions Before and After Periodontal Therapy: A Case Series from an RCT.

To investigate the effect of vitamin C supplementation with or without flavonoids on periodontal conditions, and microbial and systemic variables before and after non-surgical periodontal treatment (NSPT). A case series derived from a randomized controlled trial was conducted to explore the effects of daily vitamin C supplementation, with or without flavonoids, on periodontal conditions. The study population was recruited from patients with periodontitis who had been referred to the Department of Periodontology at the Academic Centre for Dentistry Amsterdam (ACTA).

The Prevalence of Metabolic Syndrome and Undiagnosed Diabetes in Periodontitis Patients and Non-Periodontitis Controls in a Dental School.

: Metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) are major global health concerns, and they often go undetected. Periodontitis shares risk factors and is associated with both conditions. Assessing MetS risk factors among dental patients, especially those with periodontitis, may contribute to early detection and prompt treatment.

Integration of Stromal Cells and Hydrogel Below Epithelium Results in Optimal Barrier Properties of Small Intestine Organoid Models.

: The barrier properties of the human small intestine play a crucial role in regulating digestion, nutrient absorption and drug metabolism. Current in vitro organotypic models consist only of an epithelium, which does not take into account the possible role of stromal cells such as fibroblasts or the extracellular matrix (ECM) which could contribute to epithelial barrier properties. Therefore, the aim of this study was to determine whether these stromal cells or ECM were beneficial or detrimental to barrier function when incorporated into an organotypic human small intestine model.

Knowledge, Attitude, and Practice of Dutch Dentists on Oral Leukoplakia and Their Possible Role in Its Follow-Up.

Objective: To assess the knowledge, attitude, and practice of Dutch dentists on oral leukoplakia (OL) and to what extent these aspects are related to whether or not dentists regularly monitor patients with OL.

Material And Methods: A self-developed questionnaire was distributed via a web survey among a sample of dentists participating in an intervision program. Of 1626 invited dentists, 437 (26.

The determination of patient-based experiences with smartphone-based report of awake bruxism using a diary.

Objectives: In recent years, a smartphone-based ecological momentary assessment (EMA) approach for assessing awake bruxism (AB) has attracted growing interest, both in clinical and research settings. The present study was designed to investigate subjects' experience using an EMA-based smartphone application to detect factors that could hamper or facilitate its use for clinical and research purposes.

Materials And Methods: Thirty-two patients with temporomandibular disorders (TMDs) pain (14 males, 18 females; mean age 28.

Relative abrasive potential of silica-based conventional and tablet dentifrices on enamel and dentin.

Objectives: This in vitro study aimed to investigate the toothbrushing wear on both enamel and dentin surfaces of reference and commercially available dentifrices.

Methods: Bovine enamel and dentin blocks were initially polished and embedded within a resin composite in square shapes (10×8×6 mm3). Employing toothbrushes equipped with nylon bristles, a toothbrushing machine was utilized, subjecting dentin specimens (n = 36) to 500 brush cycles and enamel samples to 5000 brush cycles (n = 36).

When trauma bites back: a systematic review on direct orofacial macrotrauma and temporomandibular disorders.

Objectives: Temporomandibular disorders (TMD) are musculoskeletal conditions with a multifactorial aetiology. The predictive role of direct orofacial macrotrauma in the development of TMD is considered controversial. This systematic review aims to elucidate the association between direct orofacial macrotrauma and TMD, and to identify potential factors involved in this relationship.

Evaluating growth-factor release in leukocyte- and platelet-rich fibrin, advanced platelet-rich fibrin, and injectable platelet-rich fibrin protocols: a narrative review.

Since its introduction in 2001, multiple platelet-rich fibrin (PRF) centrifugation protocols have emerged, but the variations in growth factor release that result from these protocols remain unclear. This review aimed to evaluate growth factor release across three PRF protocols: leukocyte-PRF (L-PRF), advanced-PRF (A-PRF/+), and injectable-PRF (i-PRF). A comprehensive search was conducted using the MEDLINE and Embase databases, identifying 14 studies that met the inclusion criteria.

Cone beam computed tomography - Frequency and exposure settings at University (Dental) hospitals in Central and Northern Europe.

Purpose: To investigate the frequency of CBCT scans, the exposure settings, volume sizes and the patient demographics (age and sex) of patients undergoing CBCT scans in university-based dental hospitals in different European countries over a one-year period.

Method: Eight University Dental Hospitals from eight countries in central and northern Europe agreed to collect data from their CBCT-databases. Exposure data including field of view (FOV), dose area product (DAP) and optimization settings plus (anonymous) age and sex of the patients were collected for the entire year 2023.

A comprehensive study on MDP effects: Microshear bond strength and fatigue resistance in 4YSZ ceramics.

The aim of this study is to assess the presence of MDP at various stages of the bonding procedure, enhance the adhesive and mechanical behavior of cemented zirconia ceramics. Fifty ceramic slices (15 × 15 × 2 mm) and 48 discs (Ø= 10 mm, 1 mm thickness) were prepared, sintered, air-abraded with aluminum oxide, and allocated considering: 1) microshear bond strength (µSBS) between ceramic slices and luting agent cylinders (height= 1 mm, Ø= 1.2 mm); 2) fatigue behavior, ceramic discs paired and bonded onto fiber-epoxy resin discs (Ø= 10 mm, 2.

From Virtual Reality to Reality: Fine-Tuning the Taxonomy for Extended Reality Simulation in Dental Education.

Introduction: Digital simulation in dental education has substantially evolved, addressing several educational challenges in dentistry. Following global lockdowns and sustainability concerns, dental educators are increasingly adopting digital simulation to enhance or replace traditional training methods. This review aimed to contribute to a uniform taxonomy for extended reality (XR) simulation within dental education.

Enhancing the effectiveness of interprofessional education in health science education: a state-of-the-art review.

Background: In order to foster effective collaboration and improve healthcare outcomes, students from multiple health professions engage in interprofessional education (IPE), learning together and from each other. Existing literature explores the effectiveness of IPE within health sciences but presents varied findings. The purpose of this study is to The effectiveness of IPE is defined as the four levels of training evaluation delineated by Kirkpatrick: reaction, learning, behavior, and results.

Mortality Among Dental Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Public Domain Database Study.

Background: This study was conducted to assess the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on dental healthcare workers (DHCWs) during the pandemic. Due to frequent exposure to aerosol-generating procedures, DHCWs are at an increased risk of a SARS-CoV-2 infection, increasing their mortality risk. Therefore, this retrospective study aimed to ascertain the mortality of DHCWs attributable to SARS-CoV-2 infection from databases in the public domain during the pandemic.

Effectiveness of fissure sealants in 8- to 10-year-olds with and without molar-incisor hypomineralization (MIH) - results from a cross-sectional epidemiological study.

Objective: This cross-sectional study aimed to investigate the use, quality, and caries-preventive effects of fissure sealants (FSs) in 8- to 10-year-olds with and without molar-incisor hypomineralization (MIH).

Materials And Methods: A total of 5,418 children (2,692 males, 2,726 females) were examined via standard instruments (dental mirrors, CPI probes, adequate lighting, mobile examination tables, and air syringes) and methods for the recording of caries (DMFT index, WHO method) and FSs. The classification of MIH followed the recommendations of the European Academy of Pediatric Dentistry (EAPD).

Sleep bruxism and GERD correlation in a general population convenience sample.

Objective: To investigate the relationship between sleep bruxism(SB) and gastroesophageal reflux disease (GERD) with the use of validated questionnaires in a general population convenience sample.

Methods: SB behaviour was evaluated in accordance with the Subject-Based Assessment strategy recommended in the Standardized Tool for the Assessment of Bruxism (STAB). .

TP8, A Novel Chondroinductive Peptide, Significantly Promoted Neo-Cartilage Repair without Activating Bone Formation.

The repair of large cartilage defects remains highly challenging in the fields of orthopedics and oral and maxillofacial surgery. A chondroinductive agent is promising to activate endogenous mesenchymal stem cells (MSCs) so as to facilitate cartilage regeneration. In this study, we analyze the crystallographic data of the critical binding domain of transforming growth factor β3 (TGF-β3) with its type II receptor and successfully develop a novel chondroinductive peptide - TGF-β3-derived peptide No.

Evaluation of the Information on Dutch Dental Practice Websites Regarding the Treatment of (Frail) Elderly Patients.

The number of elderly people worldwide and their need for dental care increases in a yearly basis. A dental practice website can be a valuable source of information to these patients that may need comprehensive or adjusted care. Therefore, this study aimed to evaluate the information on Dutch general dental practice websites on topics relevant to the treatment of (frail) elderly patients.

The Prevalence of Comorbidities in Individuals with Periodontitis in a Private Periodontal Referral Practice.

Periodontitis (PD) patients frequently suffer from comorbidities, necessitating increased attention to disease management and monitoring. The aim of this study is to describe the prevalence and patterns of comorbidities among patients with PD in a private periodontal referral practice. This study involved 3171 adults with PD.

Association between lesion depth and placement technique with failures requiring extraction of preformed metal crowns in primary molars. A retrospective study.

Purpose: The aim of the present study was to evaluate the factors associated with failure requiring extraction after placement of preformed metal crowns (PMCs) in primary molars. Radiographic caries depth at baseline (initial/moderate and severe) and placement technique (Conventional and Hall technique) and other patient-related variables were analysed.

Methods: Clinical and radiographic records from children aged 2-10 years who had at least one primary molar treated with PMCs between 2011 and 2019 were evaluated.

Health literacy, oral diseases, and contributing pathways: results from the Lifelines Cohort Study.

Objective: Health literacy (HL), the ability to deal with information related to one's health, may affect oral health via several routes. Therefore, this study aimed to examine the association of HL with oral diseases, and whether this association is mediated by oral health behaviour and dental care utilisation.

Methods: We included 26,983 participants from the prospective multigenerational Dutch Lifelines Cohort Study to estimate the association between limited health literacy, and self-reported oral health outcomes (edentulism and gingivitis), and mediation by oral health behaviour and dental care utilisation.

Detecting Colorectal Neoplasia Using Specific Fecal Fluorogenic Protease-Sensitive Substrates: A Pilot Study.

Background: identification and removal of advanced adenomas (AA) reduce colorectal cancer (CRC) incidence and potentially mortality. CRC screening often uses fecal immunochemical testing to select high-risk individuals for colonoscopy, despite its low sensitivity for AA and relatively high false-positivity rate. Previous studies have linked proteases to CRC development through their ability to facilitate angiogenesis and immunoregulation.