1 results match your criteria: "Centre for Cognition and Neurodegeneration Research[Affiliation]"
Cognitive enhancing effects of ghrelin receptor agonists.
Psychopharmacology (Berl)
October 2009
GlaxoSmithKline R&D China, Centre for Cognition and Neurodegeneration Research, Biopolis at One-North, 11 Biopolis Way, The Helios Building, #03-01/02, Singapore 138667, Singapore.
Rationale: Ghrelin, the endogenous ligand for the growth hormone secretagogue receptor, has been shown to play a role in multiple physiological processes including appetite regulation, metabolism and, more recently, dendritic spine architecture, long-term potentiation and cognition.
Objective: The objective of this study was to determine the effects of two structurally non-peptide ghrelin receptor agonists (GSK894490A and CP-464709-18) on rodent cognition.
Methods: All experiments were performed in male Lister hooded rats.