Effect of "magic chlorine" in drug discovery: an approach.

The chlorine atom plays a vital role in drug design, yet the benefits of chlorine in 250 FDA-approved chlorine-containing drugs have not been studied properly. To see the "magic chloro" effect, computational studies have been carried out for 35 inhibitors, which are numbered as 12 complexes with (parent (-H), one chlorine, or two chlorine) substituents. The physicochemical properties are studied by conceptual density functional theory (CDFT).

Corrigendum: Vesicles-mediated resistance to antibiotics in bacteria.

[This corrects the article on p. 758 in vol. 6, PMID: 26257725.