New triorganotin(iv) compounds with aromatic carboxylate ligands: synthesis and evaluation of the pro-apoptotic mechanism.

Three new organotin(iv) carboxylate compounds were synthesized and structurally characterized by elemental analysis and FT-IR and multinuclear NMR (H, C, Sn) spectroscopy. Single X-ray crystallography reveals that compound C2 has a monoclinic crystal system with space group 2/ having distorted bipyramidal geometry defined by CSnO. The synthesized compounds were screened for drug-DNA interactions UV-Vis spectroscopy and cyclic voltammetry showing good activity with high binding constants.