The effect of layered double hydroxide on fluoride release and recharge from a commercial and an experimental resin varnish.

Objectives: Layered Double Hydroxide (LDH) is capable of fluoride anion exchange and release. This study investigated the effects of incorporating ZnAl-LDH in commercial and experimental dental varnishes, on fluoride release and re-release after charging in NaF.

Methods: Five discs of each material (commercial ClinproXT varnish and experimental light cured resin varnish), with and without 9%ZnAl-LDH were immersed and agitated in deionised water (DW) at 37 °C.

Layered Double Hydroxide Fluoride Release in Dental Applications: A Systematic Review.

This systematic review appraises studies conducted with layered double hydroxides (LDHs) for fluoride release in dentistry. LDH has been used as antacids, water purification in removing excess fluoride in drinking water and drug delivery. It has great potential for controlled fluoride release in dentistry, e.

An overview of periodontal regenerative procedures for the general dental practitioner.

The complete regeneration of the periodontal tissues following periodontal disease remains an unmet challenge, and has presented clinicians with a remarkably difficult clinical challenge to solve given the extensive research in this area and our current understanding of the biology of the periodontal tissues. In particular as clinicians we look for treatments that will improve the predictability of the procedure, improve the magnitude of the effect of treatment, and perhaps most importantly in the long term would extend the indications for treatment beyond the need for single enclosed bony defects to allow for suprabony regeneration, preferably with beneficial effects on the gingival soft tissues. A rapid development in both innovative methods and products for the correction of periodontal deficiencies have been reported during the last three decades.

The role of immediate provisional restorations on implants with a hydrophilic surface: A randomised, single-blind controlled clinical trial.

Objectives: To compare the radiographic bone changes, clinical parameters and aesthetic outcomes of immediately provisionalised and conventionally restored implants at 12- and 24-months post-implant placement.

Material And Methods: In 24 patients, 24 bone level implants with a hydrophilic (SLActive) surface were placed in healed sites and they were either immediately provisionalised with a non-occluding temporary crown (test group) or left without a crown (control group). In both groups, the definitive restoration was placed 16 weeks after implant placement.

Synthesis of novel chlorhexidine spheres with controlled release from a UDMA-HEMA resin using ultrasound.

Objective: Establish the release kinetics of new chlorhexidine particles incorporated in a dental resin, and with the application of ultrasound.

Methods: Spherical chlorhexidine particles (SCP) were synthesized (5wt%), freeze dried and incorporated into UDMA-HEMA resins. Chlorhexidine diacetate (CDP) (5wt%) was similarly incorporated in separate resins.

Circulating NK cells and their subsets in Behçet's disease.

Behçet's disease (BD) is an autoinflammatory, chronic relapsing/remitting disease of unknown aetiology with both innate and acquired immune cells implicated in disease pathogenesis. Peripheral blood natural killer (NK) cells and their CD56 /CD56 subsets were surface phenotyped using CD27 and CD16 surface markers in 60 BD patients compared to 60 healthy controls (HCs). Functional potential was assessed by production of interferon (IFN)-γ, granzyme B, perforin and the expression of degranulation marker CD107a.

Interfacial modulus mapping of layered dental ceramics using nanoindentation.

Purpose: The aim of this study was to test the modulus of elasticity () across the interfaces of yttria stabilized zirconia (YTZP) / veneer multilayers using nanoindentation.

Materials And Methods: YTZP core material (KaVo-Everest, Germany) specimens were either coated with a liner (IPS e.max ZirLiner, Ivoclar-Vivadent) (Type-1) or left as-sintered (Type-2) and subsequently veneered with a pressable glass-ceramic (IPS e.

Osteoporotic Animal Models of Bone Healing: Advantages and Pitfalls.

The aim of this review was to summarize the advantages and pitfalls of the available osteoporotic animal models of bone healing. A thorough literature search was performed in MEDLINE via OVID and EMBASE to identify animal studies investigating the effect of experimental osteoporosis on bone healing and bone regeneration. The osteotomy model in the proximal tibia is the most popular osseous defect model to study the bone healing process in osteoporotic-like conditions, although other well-characterized models, such as the post-extraction model, might be taken into consideration by future studies.

The effect of experimental osteoporosis on bone regeneration: part 2, proteomics results.

Objectives: To identify and describe protein expression in a Wistar rat calvarial critical size defect (CSD) model following treatment with guided bone regeneration in healthy and osteoporotic conditions.

Material And Methods: Thirty-six 10-month-old female Wistar rats were used. Half of them were ovariectomized (OVX) and fed with a low-calcium diet to induce an osteoporotic-like status.

The effect of experimental osteoporosis on bone regeneration: Part 1, histology findings.

Objectives: To histologically define the healing events occurring in calvarial critical size defects (CSDs) following treatment with a collagen barrier for guided bone regeneration (GBR) and a particulate graft in healthy and osteoporotic conditions.

Material And Methods: Thirty-six 10-month-old, female, Wistar rats were used in this study. Half of them were ovariectomized (OVX) and fed with a low-calcium diet to induce an osteoporotic-like status.

Peri-implant and periodontal microbiome diversity in aggressive periodontitis patients: a pilot study.

Aim: To investigate the bacterial microbiome in periodontal and peri-implant biofilms deriving from aggressive periodontitis patients (AgP) in conditions of health and disease.

Material And Methods: Ninety-one plaque samples were collected from 18 patients previously diagnosed and treated for AgP. The samples were taken from (i) 24 residual periodontal pockets (TD) (n = 6 patients), (ii) 24 healthy periodontal sites (TH) (n = 6 patients), (iii) 24 dental sites from the same implant patients (TM) (n = 6 patients), (iv) 5 peri-implantitis sites (II) (n = 2 patients), (v) 6 peri-mucositis sites (IM) (n = 2 patients) and (vi) 8 healthy implant sites (IH) (n = 2 patients).

Guided bone regeneration in osteoporotic conditions following treatment with zoledronic acid.

Objectives: To evaluate new bone formation in calvarial critical size defects (CSD) under dense polytetrafluoroethylene (d-PTFE), microporous membranes for guided bone regeneration (GBR) in healthy, osteoporotic and osteoporotic treated with zoledronic acid (ZA) rats.

Methods: Forty-eight, female, 6-month old Wistar rats were included in the study. Osteoporosis was induced by ovariectomy (OVX) and calcium-deficient diet in 32 rats.

Experimental models for contamination of titanium surfaces and disinfection protocols.

Aim: The aim of this pilot study was to describe an in vitro model of peri-implantitis microcosm for contamination of titanium surfaces and an in vivo model for evaluating different disinfection strategies of titanium surfaces.

Materials And Methods: Biofilms were grown in vitro for 30 days on sandblasted large-grit acid-etched (SLA) Ti discs (n = 69) in a constant depth film fermentor (CDFF) associated with peri-implantitis conditions. Four Swedish loop rabbits were randomly allocated in three test groups (T , T , T ) and one control group (C).

Microscopy and supporting data for osteoblast integration within an electrospun fibrous network.

This data article contains data related to the research article entitled "3D imaging of cell interactions with electrospun PLGA nanofiber membranes for bone regeneration" by Stachewicz et al. [1]. In this paper we include additional data showing degradation analysis of poly(d,l-lactide-co-glycolide acid) (PLGA) electrospun fibers in medium and air using fiber diameter distribution histograms.

A systematic review of implant outcomes in treated periodontitis patients.

Objectives: To investigate the effect of treated periodontitis on implant outcomes in partially edentulous individuals compared with periodontally healthy patients.

Material And Methods: Longitudinal studies reporting on implant survival, success, incidence of peri-implantitis, bone loss and periodontal status, and on partially dentate patients with a history of treated periodontitis were included.

Results: The search yielded 14,917 citations.

3D imaging of cell interactions with electrospun PLGA nanofiber membranes for bone regeneration.

Unlabelled: The interaction between resident cells and electrospun nanofibers is critical in determining resultant osteoblast proliferation and activity in orthopedic tissue scaffolds. The use of techniques to evaluate cell-nanofiber interactions is critical in understanding scaffold function, with visualization promising unparalleled access to spatial information on such interactions. 3D tomography exploiting focused ion beam (FIB)-scanning electron microscopy (SEM) was used to examine electrospun nanofiber scaffolds to understand the features responsible for (osteoblast-like MC3T3-E1 and UMR106) cell behavior and resultant scaffold function.

The effect of spark plasma sintering on lithium disilicate glass-ceramics.

Objectives: To evaluate the effects of spark plasma sintering (SPS) on the microstructure of lithium disilicate glass-ceramics.

Methods: IPS e.max CAD glass-ceramic samples were processed using spark plasma sintering (SPS) and conventionally sintered (CS) as a comparison.

In Vitro Ability of a Novel Nanohydroxyapatite Oral Rinse to Occlude Dentine Tubules.

Objectives. The aim of the study was to investigate the ability of a novel nanohydroxyapatite (nHA) desensitizing oral rinse to occlude dentine tubules compared to selected commercially available desensitizing oral rinses. Methods.

Is there a role for community pharmacists in promoting oral health?

Aim: The main aim of the present study was to investigate whether pharmacists recognised that they have a role in the promotion of oral health advice within the community.

Methods: A cross sectional survey was conducted using a structured questionnaire which was distributed to randomly selected pharmacies (n = 1,500) in the London area.

Results: Six hundred and forty-five pharmacies (43%) responded to the initial invitation and 589 (39%) of pharmacy participants acknowledged that pharmacists should have a role in oral health promotion.

The Efficacy of Selected Desensitizing OTC Products: A Systematic Review.

Objectives. The aim of the present study was to review the published literature in order to identify relevant studies for inclusion and to determine whether there was any evidence on the clinical effectiveness of selected desensitizing toothpastes, calcium sodium phosphosilicate (CSPS), amorphous calcium phosphate (ACP), nanohydroxyapatite, and casein phosphopeptide-amorphous calcium phosphate (tooth mousse) on reducing dentine hypersensitivity (DH). Materials and Methods.

Preferences of UK-Based Dentists When Undertaking Root Coverage and Regenerative Procedures: A Pilot Questionnaire Study.

Objectives. The purpose of the present study was to evaluate the awareness and preferences of registered United Kingdom (UK) dentists specialising or with an interest in periodontics in root coverage and regenerative procedures. Methods.

Dentine hypersensitivity--guidelines for the management of a common oral health problem.

Unlabelled: Dentine hypersensitivity (DHS) remains a worldwide under-reported and under-managed problem, despite making some dental treatments more stressful than necessary and having a negative impact on the patient's quality of life. This article is designed to build dental professionals' confidence and remove any confusion regarding the diagnosis, prevention and treatment of sensitive teeth caused by dentine hypersensitivity in those patients known to be at risk. There is a need for simple guidelines, which can be readily applied in general practice.

Crystallization of high-strength nano-scale leucite glass-ceramics.

Objectives: Fine-grained, high strength, translucent leucite dental glass-ceramics are synthesized via controlled crystallization of finely milled glass powders. The objectives of this study were to utilize high speed planetary milling of an aluminosilicate glass for controlled surface crystallization of nano-scale leucite glass-ceramics and to test the biaxial flexural strength.

Methods: An aluminosilicate glass was synthesized, attritor or planetary milled and heat-treated.

Reduced wear of enamel with novel fine and nano-scale leucite glass-ceramics.

Objectives: Leucite glass-ceramics used to produce all-ceramic restorations can suffer from brittle fracture and wear the opposing teeth. High strength and fine crystal sized leucite glass-ceramics have recently been reported. The objective of this study is to investigate whether fine and nano-scale leucite glass-ceramics with minimal matrix microcracking are associated with a reduction in in vitro tooth wear.