[Prenatal diagnosis of trisomy 21: the Tunisian experience].

Unlabelled: Down syndrome (Trisomy 21) is the most common fetal chromosomal abnormality in humans. Its clinical signs are now well known. Methods for prenatal screening have advanced substantially in the past two decades.

[Eclampsia: epidemiological aspects and management of 28 patients].

Aim: To ascertain the characteristics, clinical features, and maternal fetal outcome in eclampsia in a tertiary referral center (Service A, CMNT).

Methods: 28 case notes were retrieved retrospectively and data was analyzed descriptively.

Results: Twenty eight pregnancies complicated by eclampsia were identified.

[Evolution of maternal mortality in a level 3 Tunisian maternity from 1998 to 2007].

Introduction: The action plan for the maternal mortality is generally based on research studies' results carried out within hospital structure.

Objectives: Determination and follow-up of the evolution of maternal mortality from 1998 to 2007 in a level 3 Tunisian maternity and identification of its main causes.

Patients And Methods: It is a retrospective study carried out between January 1998 and December 2007.

[Pelvic actinomycosis in Tunisia: five cases].

Actinomycosis is a rare suppurative disease due to Actinomyces species. These Gram-positive, non-acid fast anaerobic filamentous bacteria are normal inhabitants of the human body, tending to reside in the oropharynx and bowel but are occasionally found in the vagina. Pelvic actinomycosis is a rare bacterial disease in women.

[Imaging of gestational trophoblastic disease].

Introduction: Trophoblastic diseases correspond to a very heterogeneous group.

Objective: To establish the importance of imaging in the management of trophoblastic diseases.

Patients And Methods: Retrospective study from 1995 to 2008, including all patients with a gestational throphoblastic disease in our department.

[Preeclampsia increases the risk of hyaline membrane disease in premature infant: a retrospective controlled study].

Objectives: Relation between preeclampsia (PE) and hyaline membrane disease (HMD) is still controversial. We found interesting to contribute to the study of this relation by comparing a HMD group to a control group with the aim to know if the risk to develop HMD was more important in case of PE.

Material And Methods: Two groups of premature infants (HMD group and control group) weighing less than 2000g and hospitalized between 1st January 2004 and 31st December 2005, were compared for data concerning mother (age, parity, diabetes, corticotherapy), PE (severity, complications, type and treatment), delivery (mode, infectious context, perinatal asphyxia) and neonatal stay (gestational age, birth, weight, sex).

Prenatal diagnosis of ectopia cordis: case report.

Unlabelled: Ectopia cordis is a rare and impressive malformation presenting as an isolated lesion or as part of the Cantrell's pentology syndrom. It is defined as an anomaly in which the fetal heart lies outside the thoracic cavity. THE AIM of the study is to report the prenatal diagnostic features and management of ectopia cordis.

[Fertiloscopy: Tunisian experiment].

Objective: The purpose of this study was to estimate the place and the results of fertiloscopy in the management of female infertility.

Materials And Methods: Retrospective study over a period of eight years including the patients presenting infertility without pathology raising of an evident surgical indication. We analyzed the perioperative data, the results as well as the complications of this intervention.

[Place of the sulprostone in therapeutic interruptions of the pregnancy].

Background: Therapeutic interruption of the pregnancies of the 2nd and 3-rd quarter is often badly accepted by the patients and it is original that his realization is easy, effective and the less traumatic possible. In this indication, the sulprostone (Nalador) is a big contribution.

Aim: The purpose of our study is to review this product, to describe our experience concerning its use in the therapeutic interruptions of pregnancies and to study alternatives in case of failure or of against indication in its use.

[Vein of Galen aneurysmal malformation: a neonatal case with unusual evolution].

We report on a neonatal patient case with a cerebral vascular dilation consistent with a vein of Galen malformation diagnosed on an antenatal doppler ultrasound examination. Antenatal diagnosis was confirmed by fetal MRI scan. After delivery, cerebral MRI scan found the same dilatation and showed no cerebral parenchymal damage.

[Endometriosis with urinary manifestation. A case report].

Endometriosis is an ectopic implantation of endometrial tissue. Authors report a case of a 33 year-old infertile women who presented a deep pelvic endometriosis infiltrating the right ureter with left ovarian endometrioma suspected by the ultrasonography and confirmed with MRI. The patient was treated with Gn-RH analogues with relief of symptoms and normalisation of the upper urinary tract.

[Uterine sarcomas: clinical and therapeutic aspects (10 cases)].

Purpose: Uterine sarcomas are rare tumours characterized by clinical and histopathological diversity and poor prognosis. We analyzed diagnostic, prognostic and therapeutic difficulties encountered with these tumors by insisting on the importance of early diagnosis.

Patients And Methods: From 1997 to 2004 ten patients with uterine sarcoma who underwent surgery in the obstetrics and gynecology unit at the Tunis maternity center were included in this retrospective study.

[Antenatal corticotherapy: ten years after the first conference of consensus].

Beneficial effects of antenatal corticotherapy on neonates are now well established. However, after the first conference of consensus, three controversial issues were left unresolved = use of dexamethasone or betamethasone, ideal number of curses to be given, and appropriateness of corticotherapy in case of prmature of the membranes. A literature review suggests that betamethasone is preferred to dexamethasone, that prscription of a single course is more advisable than multiple courses, and that antenatal corticotherapy is finally not contraindication in case of premature rupture of membranes.

[Spinal anaesthesia for Caesarean section: dose injection speed have an effect on the incidence of hypotension?].

Objective: To study effect of injection rate on spinal blockade and haemodynamic of spinal bupivacaine for Caesarean section.

Study Design: Prospective and randomized.

Patients And Methods: Sixty ASA I-II patients scheduled for elective Caesarean section were randomized to receive either fast (20 seconds, group R, n=30) or slow (60 seconds, group L, n=30) spinal injection of 10 mg of hyperbaric bupivacaine 0.

[Diagnosis of holoprosencephalia. Report of 17 cases].

Objective: To establish the epidemiologic profile of holoprosencephalia and determine benefits of ultrasound and foetopathologic examination to the diagnostic. METHODS AN MATERIAL: [corrected] Retrospective study about 17 cases of holoprosencephalia observed in CMNT between Janaury 1992 and September 2000.

Results: Ultrasound diagnosis was made in 13 cases (75%).

[Tracheal atresia. A case report].

The tracheal agenesis is a rare malformation of the respiratory tract. It must be suspected in any new born with respiratory distress, absence of crying, and difficulty or impossibility of intubation. Since the initial case report by Payne in 1900, 87 cases have been reported in the literature.

[Enecphalocele: 26 retrospective cases at the Maternal and Neonatal Center of La Rabta, Tunis].

Encephalocel is leff frequent than spina bifida and anencephalia. Its incidence is 0.25@1000 births.

[Value of fetal MRI in the prenatal diagnosis of renal polycystic disease: a case report].

We present a case of foetal polycystic kidney disease diagnosed at 34 weeks of gesttion thanks to resonance imaging (MRI). MRI demonstrated enlarged foetal kidneys that were low signal intensity on T1 weighted images and high signal intensity on T2 weighted images. These MRI findings suggested a high water containing of the renal parenchyma.

[Fetal pathology study of 88 cases of letal spina bifida].

Lethal spina bifida continue to be frequent in Tunisia; we report 88 cases of letal spina bifida: 1.05 per thousand births. This pathology was more frequent with women.

[Spontaneous rupture of the upper urinary tract in a pregnant woman. Value of ultrasonography and computed tomography in the diagnosis and treatment].

We report the eighteenth case of spontaneous rupture of the upper urinary tract in a pregnant woman (age = 24 years, term = 28 weeks). Sonography showed an anechogenic collection in the left perirenal area. Computed tomography confirmed the diagnosis of rupture.