Could Horse Gait and Induced Pelvic Dynamic Loads in Female Equestrians Be a Risk Factor in Pudendal Neuralgia?

Pudendal Neuralgia (PN) is a rare, debilitating disease caused by damage to the pudendal nerve, which innervates the anus, rectum, perineum, lower urinary tract, and genitalia. Although its etiology remains scientifically unknown, a number of sports practices, including horse-riding, are reported as triggering and/or aggravating factors. The present work summarizes the experimental measurements of the contact pressure at the interface between the rider and saddle, for a population of 12 experienced female riders.

Mental Fatigue Effects on the Produced Perception of Effort and Its Impact on Subsequent Physical Performances.

The purpose of this study was to investigate the relationship between mental fatigue induced by a demanding cognitive task and impaired physical performance in endurance due to a higher perception of effort. A total of 12 healthy adults and volunteers, who had previously practiced endurance activities for 4 to 8 h per week, performed a one-hour cognitive task involving either the process of response inhibition (Stroop task) or not (visualization of a documentary as control task), then 20 min of pedaling on a cycle ergometer at a constant perception of effort while cardio-respiratory and neuromuscular functions were measured. The Stroop task induces subjective feelings of mental fatigue (vigor: 3.

Optimization of use-wear detection and characterization on stone tool surfaces.

Debates and doubt around the interpretation of use-wear on stone tools called for the development of quantitative analysis of surfaces to complement the qualitative description of traces. Recently, a growing number of studies showed that prehistoric activities can be discriminated thanks to quantitative characterization of stone tools surface alteration due to use. However, stone tool surfaces are microscopically very heterogeneous and the calculated parameters may highly vary depending on the areas selected for measurement.

A Multifeature Learning and Fusion Network for Facial Age Estimation.

Age estimation from face images has attracted much attention due to its favorable and many real-world applications such as video surveillance and social networking. However, most existing studies usually learn a single kind of age feature and ignore other appearance features such as gender and race, which have a great influence on the age pattern. In this paper, we proposed a compact multifeature learning and fusion method for age estimation.

Impact of pulsed electric fields on vacuum drying kinetics and physicochemical properties of carrot.

The effect of pulsed electric fields (PEF) on the kinetics of vacuum drying (VD) and rehydration of carrot tissue was studied. The intensity of PEF treatment was E = 0.6 kV/cm and the total PEF treatment duration was t = 0.

Quantification of the Morphological Signature of Roping Based on Multiscale Analysis and Autocorrelation Function Description.

Roping or ridging is a visual defect affecting the surface of ferritic stainless steels, assessed using visual inspection of the surfaces. The aim of this study was to quantify the morphological signature of roping to link roughness results with five levels of roping identified with visual inspection. First, the multiscale analysis of roughness showed that the texture aspect ratio S computed with a low-pass filter of 32 µm gave a clear separation between the acceptable levels of roping and the non-acceptable levels (rejected sheets).

Determination of an Objective Criterion for the Assessment of the Feasibility of an Instrumented Indentation Test on Rough Surfaces.

The influence of roughness on the results of indentation testing was investigated using a semianalytical model. This model used simulated surfaces that were described using three standard roughness parameters: the root-mean-square deviation S, the wavelength (or cut-off of Gaussian high-pass filter), and the fractal dimension. It was shown that S had the largest effect on the determination of the macrohardness, while the surface wavelength and fractal dimension had negligible effects at the scale of investigation.

Mechanisms of pollutant-induced toxicity in skin and detoxification: Anti-pollution strategies and perspectives for cosmetic products.

With the development of industry and increase in road traffic, atmospheric pollution has reached unprecedented levels in many regions of the world. Concentrations of pollutants are often far beyond the recommendations of the World Health Organization. Skin, as the first interface between the human body and its environment, is one of the main organs exposed to pollutants and to other environmental factors such as UV irradiation.

Ultrasound assisted purification of polyphenols of apple skins by adsorption/desorption procedure.

The ultrasound (US) assisted purification of polyphenols of apple skins by adsorption/desorption on the poly-aromatic Amberlite adsorbent XAD-16 was studied. The adsorption steps were done at different temperatures (T = 25-40 °C) with application of US at different intensities (P = 0-400 W). The desorption steps were tested in aqueous ethanol solution at different concentrations of ethanol (C = 0-96%).

One-Pot FDCA Diester Synthesis from Mucic Acid and Their Solvent-Free Regioselective Polytransesterification for Production of Glycerol-Based Furanic Polyesters.

A one pot-two step procedure for the synthesis of diethyl furan-2,5-dicarboxylate (DEFDC) starting from mucic acid without isolation of the intermediate furan dicarboxylic acid (FDCA) was studied. Then, the production of three different kinds of furan-based polyesters- polyethylene-2,5-furan dicarboxylate (PEF), polyhydropropyl-2,5-furan dicarboxylate(PHPF) and polydiglycerol-2,5-furandicarboxylate (PDGF)-was realized through a Co(Ac)₂·4H₂O catalyzed polytransesterification performed at 160 °C between DEFDC and a defined diol furan-based prepolymer or pure diglycerol. In parallel to polymerization process, an unattended regioselective 1-OH acylation of glycerol by direct microwave-heated FDCA diester transesterification led to the formation of a symmetric prepolymer ready for further polymerization and clearly identified by 2D NMR sequences.

A multi-layered nerve guidance conduit design adapted to facilitate surgical implantation.

Background And Aims: The gold standard procedure after a severe nerve injury is the nerve autograft, yet this technique has drawbacks. In recent years, progress has been made in the development of artificial nerve guides to replace the autograft, but no device has been able to demonstrate superiority. The present study introduces an adaptable foundation design for peripheral nerve regeneration.

Correlations between disintegration degree of fruit skin cells induced by ultrasound and efficiency of bio-compounds extraction.

The ultrasound (US) assisted extraction of bio-compounds from different fruit skins (apples, bananas and persimmons) was studied. The aqueous suspensions of skins were treated by US with different energy inputs (0.033-0.

Emerging techniques for cell disruption and extraction of valuable bio-molecules of microalgae Nannochloropsis sp.

Microalgae of Nannochloropsis sp. present valuable source of bio-molecules (pigments, lipids, proteins) that have nutritional potential for the prevention and treatment of human diseases. Moreover, some species of Nannochloropsis are the promising sources of biofuels and excellent candidates for the replacement of classical biofuel crops.

Flax phenolic compounds as inhibitors of lipid oxidation: Elucidation of their mechanisms of action.

Polyunsaturated fatty acids are particularly sensitive to the damages due to reactive oxygen species and lipid oxidation has been reported to be involved in the degradation of food as well as in the early stages of several diseases. Our objective was to study the mechanisms of action of flax (Linum usitatissimum) phenolic compounds to prevent membrane lipid oxidation. To do so, several biophysical techniques (oxidative stress, surface tension, fluorescence spectroscopy and HPLC) were used to investigate the ability of the compounds to prevent lipid oxidation and to interact with membranes.

Metal-Free Reduction of Nitrobenzene to Aniline in Subcritical Water.

An environmentally friendly approach for the reduction of nitrobenzene to aniline promoted by carbonaceous bio-based materials was successfully achieved under subcritical water conditions. The proposed methodology features a metal-free process, no-hydrogen input as reductor, the use of commercial bio-based carbon materials having low cost and availability, and water as green solvent under subcritical conditions. Using optimized conditions, reduction of nitrobenzene in the presence of commercial NORIT GAC 12-40 or DACARB PC1000 was accomplished at 310 °C for 6 h and quantitatively furnished the target aniline.

Impact of ultrasounds and high voltage electrical discharges on physico-chemical properties of rapeseed straw's lignin and pulps.

In this study, ultrasound (US) and high voltage electrical discharges (HVED) were combined with chemical treatments (soda or organosolv) for rapeseed straw delignification. Delignification was improved by both physical pretreatments. US increased the extractability of hemicelluloses and HVED induced a partial degradation of cellulose.

Impact of TIEG1 on the structural properties of fast- and slow-twitch skeletal muscle.

Introduction: Transforming growth factor-beta (TGF-β)-inducible early gene-1 (TIEG1) is a transcription factor that is highly expressed in skeletal muscle. The purpose of this study was to characterize the structural properties of both fast-twitch (EDL) and slow-twitch (soleus) muscles in the hindlimb of TIEG1-deficient (TIEG1 ) mice.

Methods: Ten slow and 10 fast muscles were analyzed from TIEG1 and wild-type (WT) mice using MRI texture (MRI-TA) and histological analyses.

Application of differential scanning calorimetry to estimate quality and nutritional properties of food products.

Over the past years, both food researchers and food industry have shown an increased interest in finding techniques that can estimate modifications in quality, nutritional, and thermophysical properties of food products during processing and/or storage. For instance, differential scanning calorimetry (DSC) has attracted the interest of scientific community because only a small amount of sample is needed for analysis. Moreover, it does not require any specific sample preparation, and is a repeatable and reliable method.

High Modulus Biodegradable Polyurethanes for Vascular Stents: Evaluation of Accelerated in vitro Degradation and Cell Viability of Degradation Products.

We have recently reported the mechanical properties and hydrolytic degradation behavior of a series of NovoSorb™ biodegradable polyurethanes (PUs) prepared by varying the hard segment (HS) weight percentage from 60 to 100. In this study, the in vitro degradation behavior of these PUs with and without extracellular matrix (ECM) coating was investigated under accelerated hydrolytic degradation (phosphate buffer saline; PBS/70°C) conditions. The mass loss at different time intervals and the effect of aqueous degradation products on the viability and growth of human umbilical vein endothelial cells (HUVEC) were examined.

Electroporation in food processing and biorefinery.

Electroporation is a method of treatment of plant tissue that due to its nonthermal nature enables preservation of the natural quality, colour and vitamin composition of food products. The range of processes where electroporation was shown to preserve quality, increase extract yield or optimize energy input into the process is overwhelming, though not exhausted; e.g.

Real-time QCM-D monitoring of cancer cell death early events in a dynamic context.

Since a few years, the acoustic sensing of whole cell is the focus of increasing interest for monitoring the cytoskeletal cellular response to morphological modulators. We aimed at illustrating the potentialities of the quartz crystal microbalance with dissipation (QCM-D) technique for the real-time detection of the earliest morphological changes that occur at the cell-substrate interface during programmed cell death. Human breast cancer cells (MCF-7) grown on serum protein-coated gold sensors were placed in dynamic conditions under a continuous medium flow.

Coupling of OECD standardized test and immunomarkers to select the most environmentally benign ionic liquids option--towards an innovative "safety by design" approach.

This paper proposed a potential industrial accompaniment to reduce ionic liquid harmfulness by a novel combination of OECD Daphnia magna standardized test and fish immunomarkers. The combination of these two tests allowed multicriteria examination of ILs impacts in different organisms and trophic levels. The work provided new data for legislation and opened a door towards an integrative environmental evaluation due to direct implications of immune system in fish and ecosystem health.

Properties and in vitro evaluation of high modulus biodegradable polyurethanes for applications in cardiovascular stents.

This study examined the suitability of a family of biodegradable polyurethanes (PUs) NovoSorb developed for the vascular stent application. These segmented PUs are formulated to be biodegradable using degradable polyester and PU blocks. A series of PUs comprising different hard segment weight percentage ranging from 60 to 100 were investigated.

Dual-porosity model of solute diffusion in biological tissue modified by electroporation.

In many electroporation applications mass transport in biological tissue is of primary concern. This paper presents a theoretical advancement in the field and gives some examples of model use in electroporation applications. The study focuses on post-treatment solute diffusion.