Neurochemical Databases: Purpose and Expectations.

The exploration of increasingly specific brain structures and their relationships, in more nuanced ways, has facilitated the generation of databases for gene expression, connectivity, cell morphology, and electrophysiology. However, neurochemistry, the study of neurochemical environment and transmission, has not yet warranted a public database, despite the plethora of data published. From our viewpoint, a neurochemical database is overdue and would allow the field of neurochemistry to develop facilitating, standardization and reference values, reproducibility, resource efficiency, preservation and accessibility of raw data, hypothesis development and exploration, and metadata analysis.

Catch-Up Saccades in Vestibulo-Ocular Reflex Deficit: Contribution of Visual Information?

Objectives: Catch-up saccades help to compensate for loss of gaze stabilization during rapid head rotation in case of vestibular deficit. While overt saccades observed after head rotation are obviously visually guided, some of these catch-up saccades occur with shorter latency while the head is still moving, anticipating the needed final eye position. These covert saccades seem to be generated based on the integration of multisensory inputs.

Prevalence and characteristics of participants in 2024: findings from a general population survey in France.

Background: Dry January is a one-month alcohol abstinence challenge for the general population running since 2013 in the United Kingdom, and 2020 in France. Dry January has gained increasing popularity among the public, but studies assessing the individual characteristics associated with awareness and participation remain sparse.

Methods: Using quota sampling, a representative sample of 5,000 French adults completed an online cross-sectional survey between 8 and 17th January 2024.

A Taybi-Linder syndrome-related RTTN variant impedes neural rosette formation in human cortical organoids.

Taybi-Linder syndrome (TALS) is a rare autosomal recessive disorder characterized by severe microcephaly with abnormal gyral pattern, severe growth retardation and bone abnormalities. It is caused by pathogenic variants in the RNU4ATAC gene. Its transcript, the small nuclear RNA U4atac, is involved in the excision of ~850 minor introns.

The role of alpha oscillations in resisting distraction.

The role of alpha oscillations (8-13 Hz) in suppressing distractors is extensively debated. One debate concerns whether alpha oscillations suppress anticipated visual distractors through increased power. Whereas some studies suggest that alpha oscillations support distractor suppression, others do not.

An Overview of Neurophenomenological Approaches to Meditation and Their Relevance to Clinical Research.

There is a renewed interest in taking phenomenology seriously in consciousness research, contemporary psychiatry, and neurocomputation. The neurophenomenology research program, pioneered by Varela, rigorously examines subjective experience using first-person methodologies, inspired by phenomenology and contemplative practices. This review explores recent advancements in neurophenomenological approaches, particularly their application to meditation practices and potential clinical research translations.

Interconnection between adolescents' and family members' sleep.

Deficient sleep has been linked to a broad range of physical, cognitive and mental health impacts, in particular during adolescence. It is thus essential to understand its underlying mechanisms, including family factors. The goal of our study was to assess through combined subjective and objective assessments, how family members' daily variations in sleep are interconnected, between parents and siblings of adolescents.

Intact ultrafast memory consolidation in adults with autism and neurotypicals with autism traits.

The processes of learning and memory consolidation are closely interlinked. Therefore, to uncover statistical learning in autism spectrum disorder (ASD), an in-depth examination of memory consolidation is essential. Studies of the last five years have revealed that learning can take place not only during practice but also during micro rest (<1 min) between practice blocks, termed micro offline gains.

Development of auditory cognition in 5- to 10-year-old children: Focus on speech-in-babble-noise perception.

Speech-in-noise perception is consistently reported to be impaired in learning disorders, which stresses the importance of documenting its developmental course in young children. In this cross-sectional study, ninety children (41 females, 5.5-11.

Rooting for Their Own Gender: Preschoolers' Selective Preference for Winners.

Children's social preferences are influenced by the relative status of other individuals, but also by their social identity and the degree to which those individuals are like them. Previous studies have investigated these aspects separately and showed that in some circumstances children prefer high-status individuals and own-gender individuals. Gender is a particularly interesting case to study because it is a strong dimension of social identity, but also one of the most prevalent forms of social hierarchy, with males conceptualised as superior to females, by adults and children alike.

Autistic and schizotypal traits exhibit similarities in their impact on mentalization and adult attachment impairments: a cross-sectional study.

Background: Deficits in mentalizing and attachment occur in the autism and schizophrenia spectrum, and their extended traits in the general population. Parental attachment and the broader social environment highly influence the development of mentalizing. Given the similarities in the symptomatology and neurodevelopmental correlates of autism spectrum disorder (ASD) and schizophrenia (SCH), it is crucial to identify their overlaps and differences to support screening, differential diagnosis, and intervention.

Identifying Transfer Learning in the Reshaping of Inductive Biases.

Transfer learning, the reuse of newly acquired knowledge under novel circumstances, is a critical hallmark of human intelligence that has frequently been pitted against the capacities of artificial learning agents. Yet, the computations relevant to transfer learning have been little investigated in humans. The benefit of efficient inductive biases (meta-level constraints that shape learning, often referred as priors in the Bayesian learning approach), has been both theoretically and experimentally established.

Intrafamilial associations of sleep multitrajectory groups between ages of 3 and 60 months in the SEPAGES cohort.

Objectives: We investigated intrafamilial sleep evolution by identifying children's sleep multitrajectory groups between 3- and 60-month of age and their association with parental sleep multitrajectory groups.

Methods: We included 180 children from the SEPAGES cohort (Grenoble, France) whose parents belonged to previously identified sleep multitrajectory groups, through group-based multitrajectory modeling, between 3 and 36months postpartum, using nighttime (NSD) and weekend daytime (DSD) sleep durations and subjective sleep loss, comprising "No," "Subjective," and "Global" sleep problems groups. Child sleep information (NSD, DSD, subjective sleep loss, night waking, and sleep onset difficulties) was collected by parental questionnaires at 3-, 12-, 36-, and 60-month.

Long-term psycho-traumatic consequences of the COVID-19 health crisis among emergency department healthcare workers.

Assess the changes in post-traumatic stress disorder (PTSD), burnout, anxiety, depression, jobstrain, and isostrain levels over time among healthcare workers in emergency departments (EDs) after successive outbreaks of COVID-19. A prospective, multicenter study was conducted in 3 EDs and an emergency medical service. Healthcare workers who participated in our previous study were invited to participate in a follow-up 16 and 18 months and completed the questionnaires to assess symptoms of PTSD, burnout, anxiety, depression, jobstrain, and isostrain.

Defining key concepts for mental state attribution.

The terminology used in discussions on mental state attribution is extensive and lacks consistency. In the current paper, experts from various disciplines collaborate to introduce a shared set of concepts and make recommendations regarding future use.

Similarity of brain activity patterns during learning and subsequent resting state predicts memory consolidation.

Spontaneous reactivation of brain activity from learning to a subsequent off-line period has been implicated as a neural mechanism underlying memory consolidation. However, similarities in brain activity may also emerge as a result of individual, trait-like characteristics. Here, we introduced a novel approach for analyzing continuous electroencephalography (EEG) data to investigate learning-induced changes as well as trait-like characteristics in brain activity underlying memory consolidation.

Deficits in congenital amusia: Pitch, music, speech, and beyond.

Congenital amusia is a neurodevelopmental disorder characterized by deficits of music perception and production, which are related to altered pitch processing. The present study used a wide variety of tasks to test potential patterns of processing impairment in individuals with congenital amusia (N = 18) in comparison to matched controls (N = 19), notably classical pitch processing tests (i.e.

Learning and memory processes in behavioural addiction: A systematic review.

Similar to addictive substances, addictive behaviours such as gambling and gaming are associated with maladaptive modulation of key brain areas and functional networks implicated in learning and memory. Therefore, this review sought to understand how different learning and memory processes relate to behavioural addictions and to unravel their underlying neural mechanisms. Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we systematically searched four databases - PsycINFO, PubMed, Scopus, and Web of Science using the agreed-upon search string.

The relationship between frontal alpha asymmetry and behavioral and brain activity indices of reactive inhibitory control.

Reactive inhibitory control plays an important role in phenotype of different diseases/different phases of a disease. One candidate electrophysiological marker of inhibitory control is frontal alpha asymmetry (FAA). FAA reflects the relative difference in contralateral frontal brain activity.

B-cell immune deficiency in twin sisters expands the phenotype of MOPDI.

Microcephalic osteodysplastic primordial dwarfism type I (MOPDI) is a very rare and severe autosomal recessive disorder characterized by marked intrauterine growth retardation, skeletal dysplasia, microcephaly and brain malformations. MOPDI is caused by biallelic mutations in RNU4ATAC, a non-coding gene involved in U12-type splicing of 1% of the introns in the genome, which are recognized by their specific splicing consensus sequences. Here, we describe a unique observation of immunodeficiency in twin sisters with mild MOPDI, who harbor a novel n.

Neural representations of statistical and rule-based predictions in Gilles de la Tourette syndrome.

Gilles de la Tourette syndrome (GTS) is a disorder characterised by motor and vocal tics, which may represent habitual actions as a result of enhanced learning of associations between stimuli and responses (S-R). In this study, we investigated how adults with GTS and healthy controls (HC) learn two types of regularities in a sequence: statistics (non-adjacent probabilities) and rules (predefined order). Participants completed a visuomotor sequence learning task while EEG was recorded.