6 results match your criteria: "Centre de Recherche des Cordeliers 15[Affiliation]"
Assessment of the breadth of binding promiscuity of heme towards human proteins.
Biol Chem
November 2022
Centre de Recherche des Cordeliers, INSERM, CNRS, Sorbonne Université, Université de Paris, Centre de Recherche des Cordeliers 15, rue de l'Ecole de Médecine, F-75006 Paris, France.
Heme regulates important biological processes by transient interactions with many human proteins. The goal of the present study was to assess extends of protein binding promiscuity of heme. To this end we evaluated interaction of heme with >9000 human proteins.
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Bull Cancer
November 2016
Service d'immunologie biologique, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris; Inserm U970, Paris Cardiovascular Research Center - PARCC, 56, rue Leblanc, 75015 Paris, France ; UMR-S970, université Paris-Descartes, Sorbonne-Paris-Cité, Paris, France ; équipe labellisée ligue contre le cancer, 56, rue Leblanc, 75015 Paris, France.
A model of calcium transport along the rat nephron.
Am J Physiol Renal Physiol
October 2013
Centre de Recherche des Cordeliers 15 rue de l'Ecole de Médecine 75006 Paris, France.
We developed a mathematical model of calcium (Ca(2+)) transport along the rat nephron to investigate the factors that promote hypercalciuria. The model is an extension of the flat medullary model of Hervy and Thomas (Am J Physiol Renal Physiol 284: F65-F81, 2003). It explicitly represents all the nephron segments beyond the proximal tubules and distinguishes between superficial and deep nephrons.
View Article and Find Full Text PDFAssociation between CST3 rs2424577 polymorphism and corpulence related phenotypes during lifetime in populations of European ancestry.
Obes Facts
December 2011
INSERM U872 Equipe 7, Centre de Recherche des Cordeliers 15 Rue de l’Ecole de Medecine, 75006 Paris, France.
Objective: Cystatin C, a protein coded by CST3 gene, is implicated in adipose tissue biology. Our hypothesis is that common variants in CST3 gene could play a role in the development of corpulence during lifetime.
Methods: Two tag SNPs were selected to capture all SNPs in the CST3 region.
Effects of triamcinolone acetonide on vessels of the posterior segment of the eye.
Mol Vis
December 2009
1INSERM, UMRS 872 Physiopathology of Ocular Diseases, Therapeutic innovations Centre de Recherche des Cordeliers 15 rue de L'Ecole de Médecine 75006 Paris France.
Purpose: This study investigates the effects of triamcinolone acetonide (TA) on retinal endothelial cells in vitro and explores the potential vascular toxic effect of TA injected into the vitreous cavity of rats in vivo.
Methods: Subconfluent endothelial cells were treated with either 0.1 mg/ml or 1 mg/ml TA in 1% ethanol.
GLUT2 mutations, translocation, and receptor function in diet sugar managing.
Am J Physiol Endocrinol Metab
May 2009
Centre de recherche des Cordeliers 15 rue de l'école de médecine, F-75006 Paris, France.
Cloned 20 years ago, GLUT2 is a facilitative glucose transporter in the liver, pancreas, intestine, kidney, and brain. It ensures large bidirectional fluxes of glucose in and out the cell due to its low affinity and high capacity. It also transports other dietary sugars, such as fructose and galactose, within the range of physiological concentrations.
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