2 results match your criteria: "Centre de Recherche Saint-Antoine (CRSA) INSERM UMRs938[Affiliation]"
Hemasphere
January 2025
Sorbonne Université, Centre de Recherche Saint-Antoine (CRSA) INSERM UMRs938, Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, AP-HP Paris France.
Front Immunol
April 2022
DIACCURATE, Paris, France.
The origin of the impaired CD4 T-cell response and immunodeficiency of HIV-infected patients is still only partially understood. We recently demonstrated that PLA2G1B phospholipase synergizes with the HIV gp41 envelope protein in HIV viremic plasma to induce large abnormal membrane microdomains (aMMDs) that trap and inactivate physiological receptors, such as those for IL-7. However, the mechanism of regulation of PLA2G1B activity by the cofactor gp41 is not known.
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