5 results match your criteria: "Centre de Référence National des Cytopénies Auto-immunes de l'Enfant (CEREVANCE) Hôpital des Enfants[Affiliation]"
Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes.
Blood
July 2019
Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, Institut Imagine, Unité Mixte de Recherche (UMR) 1163, INSERM, Paris, France.
Evans syndrome (ES) is a rare severe autoimmune disorder characterized by the combination of autoimmune hemolytic anemia and immune thrombocytopenia. In most cases, the underlying cause is unknown. We sought to identify genetic defects in pediatric ES (pES), based on a hypothesis of strong genetic determinism.
View Article and Find Full Text PDFEvaluation of the efficiency of hydroxychloroquine in treating children with immune thrombocytopenia (ITP).
Am J Hematol
May 2017
Pediatric Hematology Unit, University Hospital of Angers, Angers, France.
Romiplostim in children with chronic immune thrombocytopenia (ITP): the French experience.
Br J Haematol
January 2014
Department of Paediatric Haematology, Hôpital des Enfants, Toulouse, France; INSERM U1037, CRCT, Toulouse, France.
A minority of children with chronic immune thrombocytopenia (ITP) require therapeutic intervention to prevent haemorrhagic risk. This retrospective national study evaluated romiplostim in childhood non-responsive or refractory chronic ITP. Between 2009 and 2012, 10 patients whose Buchanan score was 3-4 were treated with romiplostim.
View Article and Find Full Text PDFNew insights into childhood autoimmune hemolytic anemia: a French national observational study of 265 children.
Haematologica
May 2011
Pediatric Hematology Unit, Centre de Référence National des Cytopénies Auto-immunes de l'Enfant (CEREVANCE) Hôpital des Enfants, Hôpital Pellegrin, CHU Bordeaux, Place Amelie Raba Leon, 33 000 Bordeaux, France.
Background: Autoimmune hemolytic anemia is a rare condition in children. Little is known about its initial presentation and the subsequent progression of the disease.
Design And Methods: Since 2004, a national observational study has been aiming to thoroughly describe cases and identify prognostic factors.