55 results match your criteria: "Centre de Biotechnologie de Borj Cédria (CBBC)[Affiliation]"
Int J Environ Health Res
June 2024
Laboratoire des Plantes Aromatiques et Médicinales, Centre de Biotechnologie de Borj Cédria (CBBC), Hammam-Lif, Tunisia.
Plants (Basel)
October 2023
Laboratoire des Grandes Cultures, Institut National de la Recherche Agronomique de Tunisie (INRAT), University of Carthage, Rue Hédi Karray, Menzah 1004, Tunisia.
Broomrapes ( spp.) are root parasitic plants that threaten agricultural production in many parts of the world. In this study, the effect of two orobanche species, and , on faba bean plants was studied in Tunisia.
View Article and Find Full Text PDFChem Biodivers
December 2023
Laboratoire des Plantes Aromatiques et Médicinales (LPAM), Centre de Biotechnologie à la Technopole de Borj Cédria (CBBC), BP 901, 2050, Hammam-lif, Tunisia.
This work aimed to investigate the variability of the chemical composition of the aromatic halophyte Crithmum maritimum L. essential oils according to the geographical origin and separated organs, using a statistical approach based on the multiple analysis of variance and the Principal Component Analyses. One hundred twenty samples were collected from three distinct bioclimatic regions (10 samples×3 provenances×4 organs).
View Article and Find Full Text PDFEpidemiologic studies keep up the proposition that vegetables can lower the risk of cancers. Acute myeloid leukemia (AML) cells exhibit high proliferative potency and have a reduced capacity of undergoing apoptosis and maturation. The beneficial effects of seem related to the organosulfur products generated upon processing of these species.
View Article and Find Full Text PDFAppl Biochem Biotechnol
November 2021
Laboratoire Des Substances Bioactives, Centre de Biotechnologie de Borj-Cedria (CBBC), BP-901, 2050, Hammam-lif, Tunisia.
Cyclic lipopeptides produced by Bacillus species exhibit interesting therapeutic potential. However, their clinical use remains limited due to their low stability, undesirable interactions with host macromolecules, and their potential toxicity to mammalian cells. The present work aims to develop suitable lipopeptide-loaded chitosan nanoparticles with improved biological properties and reduced toxicity.
View Article and Find Full Text PDFMar Drugs
January 2021
Institut Pascal, CNRS, SIGMA Clermont, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.
Exopolysaccharide (EPS) from marine microalgae are promising sources of a new generation of drugs. However, lot of them remain to be discovered and tested. In this study, EPS produced by and its oligomers prepared by High Pressure Homogenizer have been tested for different biological activities, i.
View Article and Find Full Text PDFJ Plant Res
January 2021
Laboratoire Des Plantes Extrêmophiles (LPE), Centre de Biotechnologie de Borj Cedria (CBBC), BP 901, 2050, Hammam Lif, Tunisie.
Despite their economic and ecological interests, Poaceae are affected by the low availability of iron in calcareous soils. Several studies focused on the capacity of this family to secrete phytosiderophores and organic acids as a mechanism of tolerance to iron deficiency. This work aimed at studying the physiological responses of two Poaceae species; Hordeum vulgare (cultivated barley) and Polypogon monspenliensis (spontaneous species) to iron deficiency, and evaluate especially the release of phytosiderophores and organic acids.
View Article and Find Full Text PDFBiochem Biophys Rep
March 2021
Graduate School of Biostudies, Kyoto University, Kyoto, 606-8502, Japan.
The extract of (Common Sage) exhibited inhibitory activity of STAT3 signal after screening of several plants extracts using the STAT3-responsive reporter system. Cirsiliol, luteolin, and carnosol were identified from the methanol extract of as inhibitors of STAT3 signaling and the effects of these three compounds on STAT3 protein or growth inhibition on cancer cells was compared. Luteolin at the dose of 90 μM clearly suppressed the phosphorylation of STAT3 induced by IL-6, while carnosol was prone to decrease total STAT3 proteins at high doses (>90 μM).
View Article and Find Full Text PDFBiol Aujourdhui
March 2022
Laboratoire des Plantes Aromatiques et Médicinales (LPAM), Centre de Biotechnologie de Borj-Cedria (CBBC), BP 901, 2050 Hammam-lif, Tunisie.
Since ancient times, plants have been the main source of bioactive molecules, such as phenolic compounds, capable of remedying various diseases. However, polyphenols' content and efficiency vary greatly as a function of several intrinsic and extrinsic factors. To optimize the procedure for the extraction of active molecules from the medicinal plant Verbena officinalis, effects of the plant origin, selected solvent, and extraction method were assessed.
View Article and Find Full Text PDFJ Proteomics
February 2021
Agroforestry and Plant Biochemistry, Proteomics and Systems Biology, Department of Biochemistry and Molecular Biology, University of Cordoba, UCO-CeiA3, 14014 Cordoba, Spain. Electronic address:
Gel electrophoresis-based and shotgun approaches are the most employed proteomic platforms in plant biology research, with the latter replacing the former in the last years. We have compared 2-DE-MALDI-TOF/TOF and GeLC-Orbitrap/MS analyses using the same protein extracts from Quercus ilex cotyledons at different development stages. The results obtained (ProteomeXchange available data, PXD020603) showed that both platforms were complementary, showing common and specific proteins identified in each case, but leading to similar biological conclusions.
View Article and Find Full Text PDFBiochim Biophys Acta Bioenerg
December 2018
Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale, viale Teresa Michel 11, 15121 Alessandria, Italy.
Plants show complex responses to abiotic stress while, the effect of the stress combinations can be different to those seen when each stress is applied individually. Here, we report on the effects of salt and/or cadmium on photosynthetic apparatus of Thellungiella salsuginea. Our results showed a considerable reduction of plant growth with some symptoms of toxicity, especially with cadmium treatment.
View Article and Find Full Text PDFInt J Biol Macromol
December 2018
Laboratoire de Biotechnologie Végétale Appliquée à l'Amélioration des Cultures, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia. Electronic address:
The production of B-phycoerythrin (B-PE) from the red microalga Porphyridium marinum was optimized before to purify it and subsequently study its antioxidant activities. NaNO KHPO and metal traces concentrations of the culture medium, and luminosity parameters were chosen, according to the Plackett-Burman design, as the most influent factors on the B-PE production by P. marinum.
View Article and Find Full Text PDFWorld J Microbiol Biotechnol
June 2018
Laboratoire des Substances Bioactives, Centre de Biotechnologie de Borj-Cedria (CBBC), BP-901, 2050, Hammam-Lif, Tunisia.
A Trichoderma orientale strain LSBA1 was isolated from the Mediterranean marine sponge Cymbaxinella damicornis. The crude extract of T. orientale mycelium showed inhibitory activity against growth of Gram-positive and Gram-negative bacteria as well as clinical isolates of Candida albicans.
View Article and Find Full Text PDFNutrients
March 2018
UMR DIATHEC, EA 7294, Fédération de Médecine Translationnelle de Strasbourg (FMTS), University of Strasbourg, Boulevard René Leriche, 67200 Strasbourg, France.
Hyperglycemia occurs during diabetes and insulin resistance. It causes oxidative stress by increasing reactive oxygen species (ROS) levels, leading to cellular damage. Polyphenols play a central role in defense against oxidative stress.
View Article and Find Full Text PDFPhysiol Plant
October 2018
Abteilung Pflanzenproteomik, Institut für Pflanzengenetik, Leibniz Universität Hannover, D-30419, Hannover, Germany.
Seed germination recovery aptitude is an adaptive trait of overriding significance for the successful establishment and dispersal of extremophile plants in their native ecosystems. Cakile maritima is an annual halophyte frequent on Mediterranean coasts, which produces transiently dormant seeds under high salinity, that germinate fast when soil salinity is lowered by rainfall. Here, we report ecophysiological and proteomic data about (1) the effect of high salt (200 mM NaCl) on the early developmental stages (germination and seedling) and (2) the seed germination recovery capacity of this species.
View Article and Find Full Text PDFFood Chem
March 2018
Departamento Ciências Agrárias, Universidade Estadual de Montes Claros, 39440-000 Janaúba MG, Brazil.
Guava is a typically tropical fruit highly perishable with a short shelf-life due to intense metabolic activity after harvested. In attempt to minimize the problems related to the postharvest, we evaluated the physiochemical characteristics and antioxidant system in guava fruits under chitosan coating at concentrations of 1%, 2%, and 3% stored at 25°C during 96h. The chitosan suppressed the respiratory rate, fresh weight loss, firmness and skin color with delay in the degradation of chlorophyll.
View Article and Find Full Text PDFJ Biol Eng
September 2017
Arab German Young Academy of Sciences and Humanities (AGYA), Working group "Energy, Water and Environment", at the Berlin-Brandenburg Academy of Sciences and Humanities, Berlin, Germany.
Due to steadily growing population and economic transitions in the more populous countries, renewable sources of energy are needed more than ever. Plant biomass as a raw source of bioenergy and biofuel products may meet the demand for sustainable energy; however, such plants typically compete with food crops, which should not be wasted for producing energy and chemicals. Second-generation or advanced biofuels that are based on renewable and non-edible biomass resources are processed to produce cellulosic ethanol, which could be further used for producing energy, but also bio-based chemicals including higher alcohols, organic acids, and bulk chemicals.
View Article and Find Full Text PDFEXCLI J
March 2017
Laboratoire des Plantes Aromatiques et Médicinales (LPAM), Centre de Biotechnologie, Technopôle de Borj Cédria (CBBC), BP 901, 2050, Hammam-Lif, Tunisie.
Rhus species are known in traditional medicine for their therapeutic virtue and their extracts showed numerous important properties including antimalarial, antimicrobial, antiviral, and hypoglycemic and anticonvulsant activities. Rhus tripartitum (Ucria) is a medicinal plant widely used in Tunisia folk medicine against chronic diarrhea and gastric ulcer. This study was designed to examine and antioxidant, anti-inflammatory and anticancer activities of four extracts of Rhus tripartitum root cortex with increasing solvent polarity (hexane, dichloromethane, methanol and water).
View Article and Find Full Text PDFPlanta
October 2017
Sorbonne Universités, UPMC Univ Paris 06, iEES, UMR 7618 (UPMC, UPEC, CNRS, IRD, INRA, Paris Diderot), Case 237, 4 Place Jussieu, 75252, Paris Cedex 05, France.
Phospholipases Dζ play different roles in Arabidopsis salt tolerance affecting the regulation of ion transport and antioxidant responses. Lipid signalling mediated by phospholipase D (PLD) plays essential roles in plant growth including stress and hormonal responses. Here we show that PLDζ1 and PLDζ2 have distinct effects on Arabidopsis responses to salinity.
View Article and Find Full Text PDFBiomed Pharmacother
June 2017
Laboratoire des Plantes Aromatiques et Médicinales, Centre de Biotechnologie de Borj-Cédria (CBBC), BP 901, 2050 Hammam-Lif, Tunisie.
In this study, two Euphorbia species (i.e. terracina and paralias) were investigated for their cytotoxic and antioxidant activities.
View Article and Find Full Text PDFJ Plant Physiol
March 2017
Laboratoire des Plantes Extrêmophiles, Centre de Biotechnologie de Borj Cedria (CBBC), BP 901, Hammam Lif 2050, Tunis, Tunisie.
The effect of HO and mannitol seed priming was investigated on plant growth, oxidative stress biomarkers and activities of antioxidant enzymes in leaves of Cakile maritima and Eutrema salsugineum, when exposed to drought and salt stress, either separately applied or combined. Under unprimed conditions, drought severely restricted growth (40% as compared to the control) and redox balance of C. maritima seedlings, whereas E.
View Article and Find Full Text PDFFunct Plant Biol
October 2016
Laboratoire des Plantes Extrêmophiles, Centre de Biotechnologie de Borj-Cedria (CBBC), BP 901, Hammam-Lif, 2050, Tunisia.
Nitric oxide (NO) - an endogenous signalling molecule in plants and animals - mediates responses to biotic and abiotic stresses. In the present study, we examined the role of exogenous application of NO in mediating stress responses in Cakile maritima Scop. seedlings under water deficit stress using sodium nitroprusside (SNP) as NO donor and as a pre-treatment before the application of stress.
View Article and Find Full Text PDFJ Genet
September 2016
Laboratoire des Plantes Extrémophiles (LPE), Centre de Biotechnologie de Borj Cédria (CBBC), BP 901, Hammam-lif 2050,
Appl Biochem Biotechnol
February 2017
Laboratoire des Substances Bioactives, Centre de Biotechnologie de Borj-Cedria (CBBC), BP-901, 2050, Hammam-lif, Tunisia.
A strain producing chitinase, isolated from potato stem tissue, was identified as Bacillus licheniformis by biochemical properties and 16S RNA sequence analysis. Statistical experimental designs were used to optimize nine independent variables for chitinase production by B. licheniformis AT6 strain in submerged fermentation.
View Article and Find Full Text PDFBiochem J
September 2016
Sorbonne Universités, UPMC Univ Paris 06, iEES, UMR 7618, UPMC Paris 06-Sorbonne (UPEC, UPMC, CNRS, IRD, INRA, Paris Diderot), case 237, 4 place Jussieu, F-75252 Paris cedex 05, France
Proline accumulates in many plant species in response to environmental stresses. Upon relief from stress, proline is rapidly oxidized in mitochondria by proline dehydrogenase (ProDH) and then by pyrroline-5-carboxylate dehydrogenase (P5CDH). Two ProDH genes have been identified in the genome of the model plant Arabidopsis thaliana To gain a better understanding of ProDH1 functions in mitochondria, proteomic analysis was performed.
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