1 results match your criteria: "Centre d'investigation clinique - Clinique neurologique[Affiliation]"
BMJ Case Rep
September 2012
CHU Nantes, Centre d'investigation clinique - Clinique neurologique, CHU Nantes, France.
Usually, levodopa-induced dyskinesia does not remain unchanged throughout the day in Parkinson's disease (PD) patients and varies according to the level of correction of PD symptomatology provided by the treatment. We observed two PD patients with unusual buccolingual masticatory movements which did not seem to fluctuate, either throughout the day during dopaminergic treatment or during a standardised levodopa challenge. After their dopaminergic treatment had been changed to a less pulsatile form of administration (ie, the use of dopamine agonist alone in the first patient and an increase in the dosage of dopamine agonist with a low dose of levodopa in the second), these abnormal movements totally disappeared in the first patient and were greatly improved in the second.
View Article and Find Full Text PDF