3 results match your criteria: "Centre d'Immunologie et des Maladies Infectieuses (CIMIParis)[Affiliation]"

SARS-CoV-2 infection fatality rate (IFR) doubles with every five years of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ~20% of deceased patients across age groups. In the general population, they are found in ~1% of individuals aged 20-70 years and in >4% of those >70 years old.

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Article Synopsis
  • Researchers tested a new HIV vaccine called MVA-B to see how it affects the immune system when given in different ways: through the skin or in the muscle.
  • They found that both ways were safe, but how the body responds to the vaccine was different depending on the route.
  • Vaccination through the skin helped activate certain immune cells better, while muscle vaccination changed how the body processes immune signals.
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Antibacterial antibody responses that target surfaces of live bacteria or secreted toxins are likely to be relevant in controlling bacterial pathogenesis. The ability to specifically quantify bacterial-surface-binding antibodies is therefore highly attractive as a quantitative correlate of immune protection. Here, binding of antibodies from various body fluids to pure-cultured live bacteria is made visible with fluorophore-conjugated secondary antibodies and measured by flow cytometry.

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