329 results match your criteria: "Centre antipoison[Affiliation]"

[Amatoxin-containing mushroom poisoning: An update].

Rev Med Interne

July 2024

Centre antipoison de Paris, fédération de toxicologie (FeTox), hôpital Fernand-Widal, AP-HP, 200, rue du Faubourg-Saint-Denis, 75010 Paris, France; Université Paris-Cité, Inserm UMR-S 1144, optimisation thérapeutique en neuropsychopharmacologie, 4, avenue de l'Observatoire, 75006 Paris, France; UFR de médecine, université de Paris, 75006 Paris, France.

Amatoxin-containing mushroom poisoning occurs after consumption of certain mushroom species, of the genera Amanita, Lepiota and Galerina. Amanita phalloides is the most implicated species, responsible for over more than 90% of mushroom-related deaths. The α-amanitin is responsible for most of the observed effects.

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[Not Available].

CMAJ

October 2023

Département de médecine, de pédiatrie et Institut des politiques, de la gestion et de l'évaluation de la santé (Juurlink), Université de Toronto; Centre antipoison de l'Ontario (De Halleux, Juurlink); Institut de recherche Sunnybrook (Juurlink), Toronto, Ont.; Institut de recherche en services de santé (Juurlink), Toronto, Ont.; Centre antipoison du Québec (De Halleux), Québec, Qc.

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The Occasional intralipid emulsion therapy.

Can J Rural Med

November 2023

Centre Intégré De Santé Et Services Sociaux De La Montérégie-Centre; Centre Antipoison Du Québec; Department of Family Medicine and Emergency Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Quebec, Canada.

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[Not Available].

CMAJ

October 2023

École Dalla Lana de santé publique de l'Université de Toronto (Gitelman, Kim); Division de médecine interne (An), Centre de santé Saint-Joseph, Réseau universitaire de santé de Toronto; Centre antipoison de l'Ontario (An), Hôpital pour enfants malades; Division de médecine du travail (Spilchuk), Faculté de médecine Temerty, Université de Toronto; Médecine du travail et de l'environnement (Spilchuk, Kim), Santé publique Ontario, Toronto, Ont.

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Diagnosis and management of toxicity associated with the recreational use of nitrous oxide.

CMAJ

August 2023

Departments of Medicine, Pediatrics, and Health Policy, Management and Evaluation (Juurlink), University of Toronto; Ontario Poison Centre (De Halleux, Juurlink); Sunnybrook Research Institute (Juurlink), Toronto, Ont.; ICES (Juurlink), Toronto, Ont.; Centre Antipoison du Québec (De Halleux), Québec, Que.

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Introduction: Female Genital Mutilation (FGM) is an intervention on the female genital organs for non-medical reasons. In France, asylum is possible for girls at risk of FGM in their country of origin. The procedure includes a forensic examination of the child.

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Introduction: Exposure to e-cigarette liquids, whether intentional or accidental, might lead to adverse events. This study aimed to describe the prevalence and characteristics of exposures to e-liquids reported to French Poison Control Centers.

Methods: All e-liquids exposure cases reported to French Poison Control Centers from July 1, 2019, to December 31, 2020, were reviewed.

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[Environmental and occupational risk factors for myelodysplastic syndrome].

Bull Cancer

November 2023

AP-HP, Hôpitaux universitaires Lariboisière-Fernand-Widal-Saint-Louis, Centre antipoison de Paris, FedTox, Paris, France. Electronic address:

Chemotherapy and radiotherapy for a previous cancer can lead to subsequent myelodysplastic syndrome (MDS). However, these therapy-related cases are hypothesized to explain only 5 % of diagnosed MDS cases. Environmental or occupational exposure to chemicals or radiations has also been reported to be associated with higher risk of MDS.

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The occupational risk of infection in forensic workers is a cause for concern, furthermore in the current context of the coronavirus disease-19 (COVID-19) pandemic. In order to characterize this risk, we performed an extended review of the literature on occupational infections occurring in forensic workers. Seventeen articles were included.

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Article Synopsis
  • The study emphasizes that while button batteries (BB) in the esophagus are recognized as emergencies, complications from BB in the intestines are not as well understood, highlighting the need for more research in this area.
  • A notable case involved a 7-month-old infant who ingested a button battery, leading to a blockage in the small intestine, which was exacerbated by his previous intestinal surgeries.
  • The literature review identified 12 severe cases of intestinal injury related to BB ingestion, suggesting that patients with a history of intestinal issues should undergo prompt endoscopic procedures to prevent serious complications like perforation or prolonged hospital stays.
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Purpose: To characterize clinical profile of pediatric local anesthetic (LA) systemic toxicity (LAST) and to identify determinants of life-threatening outcomes.

Methods: Spontaneous reports notified to the French Pharmacovigilance Network were retrieved and followed by a case-by-case review, according to the following criteria: LA as suspected drug, age < 18 years, adverse drug reactions related to nervous system, cardiac, respiratory, psychiatric or general disorders. Multivariate logistic regression analysis was performed to identify factors leading to life-threatening reaction (i.

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Article Synopsis
  • GHB is produced naturally from GABA or can be obtained from substances like 1,4-butanediol and GBL, which are quickly converted to GHB in the body.
  • When ingested, GHB has a rapid absorption rate and its effects vary based on dosage, often leading to neurological disorders and potential withdrawal symptoms with long-term use.
  • While GHB is regulated internationally due to its association with abuse and drug-facilitated crimes, substances like GBL and 1,4-BD are not as strictly controlled, necessitating careful monitoring to prevent misuse and related health risks.
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[Towards comprehensive care for victims of violence].

Rev Prat

April 2023

Unité médicojudiciaire, Hôtel-Dieu, AP-HP. Paris, France 6. Centre antipoison de Paris, Fédération de toxicologie (FeTox), hôpital Fernand-Widal, AP-HP. Paris, France. UFR de médecine, université de Paris-Cité, Paris, France.

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Introduction: Canadian Indigenous populations have a high incidence of poisoning; it has been suggested that care provided to the population living in remote areas is suboptimal. Our study aims to compare the continuum of care of poisoned people in Indigenous communities with those in non-Indigenous communities located in rural regions in the province of Québec.

Methods: We conducted a multicenter retrospective cohort study using data from the Center Antipoison du Québec (CAPQ) over a 2-year period (2016-2017).

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A French study of cocaine intoxication/exposure in children (2010-2020).

Clin Toxicol (Phila)

May 2023

Service d'accueil des Urgences Pédiatriques, Hôpital des Enfants, CHU Toulouse, France.

Article Synopsis
  • In the EU, cocaine availability has risen, with increased purity, leading to a significant rise in pediatric cocaine toxicity cases, particularly in children under 6.
  • A study over 11 years showed an eightfold increase in admissions for cocaine intoxication, with severe clinical symptoms, primarily neurologic and cardiovascular.
  • The findings highlight that as cocaine trends worsen, the health risks for children are escalating, marking a critical public health issue.
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[Adverse effects of licorice consumed as food: An update].

Rev Med Interne

September 2023

Centre antipoison de Paris, Fédération de toxicologie (FeTox), hôpital Fernand-Widal (AP-HP), 200, rue du faubourg Saint-Denis, 75010 Paris, France; Université Paris Cité, Inserm UMR-S 1144, optimisation thérapeutique en neuropsychopharmacologie, 75006 Paris, France; UFR de médecine, université de Paris, 75006 Paris, France.

Article Synopsis
  • Licorice refers to a plant and its roots, especially Glycyrrhiza glabra, which is widely used in herbal medicine, food, cosmetics, and pharmaceuticals.
  • Glycyrrhizin, a key component of licorice, is processed in the body into metabolites that can lead to health issues like apparent mineralocorticoid excess syndrome, particularly after chronic high doses.
  • Symptoms of glycyrrhizin poisoning include hypertension and fluid retention, and the diagnosis involves clinical evaluation and lab tests, with treatment focusing on symptom relief and discontinuing licorice use.
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Effect of Taste Additives on the Palatability of Activated Charcoal: a Systematic Review.

J Med Toxicol

July 2023

CHU de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma - Emergency - Critical Care Medicine), Québec City, Québec, Canada.

Introduction: Activated charcoal is a decontaminating agent used for acute intoxication. It can be mixed with taste additives to overcome its poor palatability. Our purpose was to evaluate the taste additives used to improve activated charcoal's palatability.

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Comparison of Machine Learning Methods in the Study of Cancer Survivors' Return to Work: An Example of Breast Cancer Survivors with Work-Related Factors in the CONSTANCES Cohort.

J Occup Rehabil

December 2023

Univ Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail), UMR_S 1085, IRSET-ESTER, SFR ICAT, Angers, F-49000, France.

Purpose: Machine learning (ML) methods showed a higher accuracy in identifying individuals without cancer who were unable to return to work (RTW) compared to the classical methods (e.g. logistic regression models).

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Beneficial Effects of ε-Viniferin on Obesity and Related Health Alterations.

Nutrients

February 2023

Nutrition and Obesity Group, Department of Nutrition and Food Science, Faculty of Pharmacy and Lucio Lascaray Research Centre, University of the Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain.

Viniferin is a phenolic compound belonging to the group of stilbenoids. In particular, ε-viniferin is a dimer of resveratrol, found in many plant genders, among which grapes () are a primary source. Due to the fact that ε-viniferin is mainly present in the woody parts of plants, their use as a source of this bioactive compound is a very interesting issue in a circular economy.

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Article Synopsis
  • Ethylene glycol (EG) can lead to serious health issues like metabolic acidemia, neurotoxicity, and acute kidney injury, and historically treatments have included supportive care, antidotes like ethanol or fomepizole, and extracorporeal treatments (ECTRs) like hemodialysis.
  • Recent systematic reviews analyzed the effectiveness of ECTRs in treating EG toxicity, showing that while EG is generally dialyzable, mortality rates varied based on glycolate concentrations, with lower rates seen in certain patient subgroups.
  • The EXTRIP workgroup provided recommendations for ECTR use alongside supportive care, suggesting it may be beneficial under specific conditions related to EG or glycolate concentrations and severe clinical features, although the quality of
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Retrospective evaluation of management guidelines for extracorporeal treatment of metformin poisoning.

Clin Toxicol (Phila)

April 2023

Division of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, NYU Grossman School of Medicine, New York, NY, USA.

Article Synopsis
  • The EXTRIP Workgroup established criteria for extracorporeal toxin removal in cases of metformin poisoning, aiming to assess the effectiveness of this treatment.
  • A retrospective study analyzed 201 patients with suspected metformin poisoning, focusing on those meeting the EXTRIP criteria, their treatment, and survival rates.
  • Results showed no survival advantage from extracorporeal toxin removal among patients meeting the EXTRIP criteria; however, those not meeting the criteria had a 100% survival rate, indicating the need for further investigation on treatment benefits.
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How to Use Biomechanical Job Exposure Matrices with Job History to Access Work Exposure for Musculoskeletal Disorders? Application of Mathematical Modeling in Severe Knee Pain in the Constances Cohort.

Int J Environ Res Public Health

December 2022

Univ. Angers, CHU Angers, Univ. Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail)-UMRS 1085, SFR ICAT, 49100 Angers, France.

Introduction: Musculoskeletal disorders related to work might be caused by the cumulative effect of occupational exposures during working life. We aimed to develop a new model which allows to compare the accuracy of duration of work and intensity/frequency associations in application to severe knee pain.

Methods: From the CONSTANCES cohort, 62,620 subjects who were working at inclusion and coded were included in the study.

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