Spatiotemporal dynamics of the oropharyngeal microbiome in a cohort of Ivorian school children.

The respiratory tract harbours microorganisms of the normal host microbiota which are also capable of causing invasive disease. Among these, Neisseria meningitidis a commensal bacterium of the oropharynx can cause meningitis, a disease with epidemic potential. The oral microbiome plays a crucial role in maintaining respiratory health.

Malaria transmission in the coastal zone and in the Centre of Côte d'Ivoire during the dry season.

Background: Malaria remains a threat in sub-Saharan Africa, particularly in Côte d'Ivoire, where it is endemic and represents the leading cause of hospital consultations, morbidity and mortality. The strong climatic variations that exist between coastal and savannah areas of Côte d'Ivoire suggest that vector control interventions should be scheduled according to the eco-epidemiological diversity. This study evaluates bioecological parameters of vectors and malaria transmission in two health districts, one coastal and one central of Côte d'Ivoire.

Assessing species composition and insecticide resistance of Anopheles gambiae complex members in three coastal health districts of Côte d'Ivoire.

Although malaria is endemic in coastal Côte d'Ivoire, updated data on the resistance profile of the main vector, Anopheles gambiae sensu lato (s.l.), are still lacking, thus compromising decision-making for an effective vector control intervention.

Environmental and socio-economic determinants of fecal sludge emptying in Sub-Saharan Africa: A cross-sectional mixed-methods study in Abidjan, Côte d'Ivoire.

This study sought to understand the determinants of household's choices for fecal sludge (FS) emptying to help fighting against unhygienic/unsafe practices and environmental pollution. A cross-sectional mixed study used in the municipality of Yopougon (Abidjan, Côte d'Ivoire), involved surveys (559 household), and 24 semi-structured interviews. Adjusted odds ratios (aORs) from logistic regressions indicated the variables significantly associated with these practices while thematic content analysis helped assessing stakeholders' perceptions.

Level of involvement of four selected cytochrome P450s (CYPs) in pyrethroid-resistant () and across Côte d'Ivoire.

In Côte d'Ivoire, there is a high intensity of pyrethroid resistance in malaria vectors which may threaten successful vector control. Molecular studies of the target site mutation in the voltage-gated sodium channel (VGSC) show that the gene frequencies of these mutations are high, widely spread across Côte d'Ivoire, and even fixed in some areas. To further characterize insecticide resistance in Côte d'Ivoire beyond target site mutations, the metabolic resistance mechanism was explored.

Efficacy of nutritional support in combination with standard Buruli ulcer treatment: A case study in Côte d'Ivoire.

Background: Buruli ulcer (BU) is an infectious skin disease caused by . It primarily affects disadvantaged rural populations and mainly impacts children who are chronically malnourished being especially vulnerable. In Côte d'Ivoire, the estimated prevalence of BU in children is 30 %.

Effect of warehouse storage on the alteration, cooking and organoleptic characteristics of yam () of Côte d'Ivoire.

Yam holds the top position in food crop production, and yam is highly prized by Ivorians. However, storage deterioration poses economic challenges for wholesalers and producers. This study assesses yam quality in warehouse storage, considering its geographical origin.

A non-human primate combinatorial system for long-distance communication.

Complex vocal systems are thought to evolve if individuals are regularly challenged by complex social decision-making, the social complexity hypothesis. We tested this idea on a West African forest non-human primate, the Olive colobus monkey, a highly cryptic species with very little social behavior and very small group sizes, factors unlikely to favor the evolution of complex communication. The species also has an unusual fission-fusion social system, with group members regularly spending considerable amounts of time with neighboring groups.

Assessing the ecological patterns of Aedes aegypti in areas with high arboviral risks in the large city of Abidjan, Côte d'Ivoire.

Background: The city of Abidjan, Côte d'Ivoire has increasingly faced multiple outbreaks of Aedes mosquito-borne arboviral diseases (e.g., dengue (DEN) and yellow fever (YF)) during the recent years, 2017-2024.

Great ape abundance and per capita carbon storage in their habitats.

The ecological importance of great apes is widely recognised, yet few studies have highlighted the role of protecting great apes' habitats in mitigating climate change, particularly through carbon sequestration. This study used GIS tools to extract data from various sources, including the International Union for Conservation of Nature database, to examine carbon quantity and great ape abundance in African great ape habitats. Subsequently, we employed a generalised linear model to assess the relationship between locally measured great ape populations abundance and carbon storage across areas with different levels of protection.

Pharmacometric Analysis to Describe Pharmacokinetics and Exposure-Efficacy Response of Ivermectin in Adolescents Infected with Trichuris trichiura.

The efficacy of the combination therapy of albendazole and ivermectin against Trichuris trichiura infection is higher in Tanzania than in Côte d'Ivoire. This study therefore aimed to investigate the difference between the population pharmacokinetics (PK) at these study sites and to determine if an exposure-response analysis could explain the low efficacy of the combination therapy in Côte d'Ivoire. Twenty-four participants (aged 12-19 years) receiving single doses of ivermectin (200 µg/kg) and albendazole (400 mg) were included in the population PK modeling.

Modeling transmission mechanism to infer treatment efficacy of different drugs and combination therapy against Trichuris trichiura.

Trichuris trichiura is one of four soil-transmitted helminth species that, collectively, are responsible for a considerable public health burden. The World Health Organization recommends preventive chemotherapy as the main intervention to eliminate soil-transmitted helminthiasis as a public health problem. Clinical trials estimated the efficacy of different drugs and treatment regimen against T.

Assessing the effects of three anthropogenic activities on the mosquito, Anopheles gambiae s.l. species composition and pyrethroid resistance mechanisms in Abidjan city, Côte d'Ivoire.

Pyrethroid resistance and mechanisms for resistance for Anopheles gambiae sensus lato (s.l.) (Diptera: Culicidae) Giles, were assessed in three urban areas (vegetable farming, industrial and residential) of Abidjan.

Potential impact of climatic factors on malaria in Rwanda between 2012 and 2021: a time-series analysis.

Background: Malaria remains an important public health problem, particularly in sub-Saharan Africa. In Rwanda, where malaria ranks among the leading causes of mortality and morbidity, disease transmission is influenced by climatic factors. However, there is a paucity of studies investigating the link between climate change and malaria dynamics, which hinders the development of effective national malaria response strategies.

The archaeological visibility of chimpanzee (Pan troglodytes) nut-cracking.

The earliest evidence for complex tool use in the archaeological record dates to 3.3 Ma. While wooden tools may have been used by our earliest ancestors, the evidence is absent due to poor preservation.

Population genetic structure and historical demography of the population of forest elephants in Côte d'Ivoire.

The population of forest elephant (Loxodonta cyclotis) has continuously declined in Côte d'Ivoire and, the remaining population largely consists of subpopulations that are fragmented and isolated. No data actually exist on the level of genetic diversity and population genetic structure of current forest elephant populations in Côte d'Ivoire. In this sense, determining genetic diversity and the underlying mechanisms of population differentiation is crucial for the initiation of effective conservation management.

Key Characteristics and Perception of Different Outbreak Surveillance Systems in Côte d'Ivoire: Cross-Sectional Survey Among Users.

Background: Accurate and timely infectious disease surveillance is pivotal for effective public health responses. An important component of this is the disease surveillance tools used. Understanding views and experiences of users is crucial for informing policy decisions and ensuring the seamless functioning of surveillance systems.

Effectiveness of Three Sampling Approaches for Optimizing Mapping and Preventive Chemotherapy against in the Western Part of Côte d'Ivoire.

The elimination of schistosomiasis as a public health problem by 2030 is one of the main goals put forth in the World Health Organization's roadmap for neglected tropical diseases. This study aimed to compare different sampling approaches to guide mapping and preventive chemotherapy. A cross-sectional parasitological survey was conducted from August to September 2022 in the health districts of Biankouma, Ouaninou, and Touba in the western part of Côte d'Ivoire.

Understanding Drug Exposure and Trichuris trichiura Cure Rates: A Pharmacometric Approach for Albendazole-Ivermectin Co-medication in Tanzania and Côte d'Ivoire.

Background And Objective: Trichuriasis caused by the human whipworm Trichuris trichiura poses a significant public health concern. Albendazole-ivermectin co-medication is currently the most effective treatment. Studies conducted in Tanzania and Côte d'Ivoire unveiled differences in efficacy for albendazole-ivermectin combination therapy in both countries.

Assessing the integration of skin screening into a mass drug administration campaign against neglected tropical diseases: A cross-sectional observational study from two districts in Côte d'Ivoire, 2023.

Background: The World Health Organization advocates integrating neglected tropical diseases (NTDs) into common delivery platforms to combat them in resource-constrained settings. However, limited literature exists on the benefits of integration. This study examines the feasibility and impact of adding skin screening to a mass drug administration (MDA) campaign in Côte d'Ivoire.