103 results match your criteria: "Centre National Hospitalier et Universitaire[Affiliation]"

Introduction: We describe the 24-month incidence of Dolutegravir (DTG)-containing antiretroviral treatment (ART) initiation since its introduction in 2019 in West Africa.

Methods: We included all patients aged 0-24 years on ART from nine clinics in Côte d'Ivoire (n=4), Ghana, Nigeria, Mali, Benin, and Burkina Faso. Baseline varied by clinic and was defined as date of first DTG prescription; patients were followed up until database closure/death/loss to follow-up (LTFU, no visit ≥7 months), whichever came first.

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Antibiotic prophylaxis practice in gastrointestinal surgery in five hospitals in southern Benin.

Infect Prev Pract

December 2024

Clinical Pharmacy and Pharmacoepidemiology research group (CLIP), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.

Background: Benin's healthcare system is characterized by a lack of local guidelines for surgical antibiotic prophylaxis (SAP), which is essential to prevent surgical site infection.

Aim: To audit compliance for SAP practices in gastrointestinal surgery.

Methods: Data were prospectively collected from gastrointestinal surgery departments in five hospitals.

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Epidemiologic, Clinical and Mycological Profile of Onychomycosis in the Hospital Setting in Benin.

Dermatol Res Pract

October 2024

Service de Dermatologie-Vénérologie, Centre National Hospitalier et Universitaire Hubert Koutoukou Maga de Cotonou, Faculté des Sciences de La Santé-Université d'Abomey-Calavi, Cotonou, Benin.

Article Synopsis
  • A total of 389 patients were seen, with 301 suspected of onychomycosis, but only 128 were confirmed through mycological testing, resulting in a 32.90% frequency of onychomycosis among nail disorders.
  • The study found that patients were mostly middle-aged women, with aesthetic concerns being the primary reason for consultation; the predominant fungi isolated were yeasts, while misunderstandings about
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Background: 10 million people are chronically infected with the hepatitis C virus (HCV) in sub-Saharan Africa. The assessment of viral genotypes and treatment response in this region is necessary to achieve the WHO target of worldwide elimination of viral hepatitis by 2030. We aimed to investigate the prevalence of HCV genotypes and outcomes of treatment with direct-acting antiviral agents in Benin, a country with a national HCV seroprevalence of 4%.

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Quality of Life and Psychiatric Comorbidities among Subjects Practicing Artificial Skin Depigmentation in 2020 in the City of Cotonou (Benin).

Dermatol Res Pract

April 2024

Service de Dermatologie-Vénérologie, Centre National Hospitalier et Universitaire Hubert Koutoukou Maga de Cotonou, Faculté des Sciences de la Santé-Université d'Abomey-Calavi (Cotonou-Bénin), Campus Universitaire Champ de Foire 01 BP. 18, Cotonou, Benin.

Introduction: The purpose of this study was to study the quality of life and psychiatric comorbidities of subjects practicing voluntary skin depigmentation in the city of Cotonou.

Methods: A cross-sectional, prospective, and analytical study, based on a three-stage probabilistic sampling method, included from June to October 2020, consenting subjects over 15 years of age, practicing artificial skin depigmentation, and residing for at least one year in Cotonou. The Dermatology Life Quality Index, Rosenberg, and Hospital Anxiety and Depression scales allowed us to evaluate the quality of life and self-esteem, and identify anxiety and depression, respectively.

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Our aim was to determine the current trend of endourology in the management of upper urinary tract calculi in Africa reference centres. We conducted an online multiple-choice questionnaire survey involving 46 centres from 27 countries using a structured well-designed Google Form (®) questionnaire. The questionnaires were distributed to the head of service through their emails.

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Background: The African Surgical Outcomes Study (ASOS) found that maternal mortality following cesarean delivery in Africa is 50 times higher than in high-income countries, and associated with obstetric hemorrhage and anesthesia complications. Mothers who died were more likely to receive general anesthesia (GA). The associations between GA versus spinal anesthesia (SA) and preoperative risk factors, maternal anesthesia complications, and neonatal outcomes following cesarean delivery in Africa are unknown.

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Introduction: Oculo-orbital tumors are common. Their clinical and histological features are multiple. The management of oculo-orbital tumors is a real challenge in sub-Saharan Africa, especially in our context.

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Article Synopsis
  • Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant public health risk, affecting patient health and increasing healthcare costs, prompting a study in six public hospitals in Benin.
  • The research involved screening patients and healthcare workers for MRSA, confirming cases through advanced microbiological methods, and utilizing whole-genome sequencing to analyze 27 high-quality MRSA isolates found among the samples collected.
  • Findings revealed various strains associated with antimicrobial resistance and identified several virulence genes, emphasizing the necessity for effective strategies to reduce MRSA transmission within hospital settings.
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Purpose: To calibrate a West-African version of the ACTIVLIM-CP questionnaire (ACTIVLIM-CP-WA) for children with cerebral palsy (CP).

Materials And Methods: We recruited 287 children with CP of various age range: 2-6 years ( = 117, preschoolers), 6-12 years ( = 96, children) and 12-19 years ( = 74, adolescents). Caregivers of children of each age range completed the experimental version of the ACTIVLIM-CP-WA including 76 (preschoolers), 78 (children) and 76 (adolescents) global daily life activities.

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Different international associations have proposed their own guidelines on urolithiasis. However, the focus is primarily on an overview of the principles of urolithiasis management rather than step-by-step technical details for the procedure. The International Alliance of Urolithiasis (IAU) is releasing a series of guidelines on the management of urolithiasis.

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[Early onset of small cell carcinom of the lung in a young patient in Benin].

Rev Mal Respir

November 2022

Centre national hospitalier et universitaire de pneumo-phtisiologie de Cotonou (CNHU/PPC), 02 BP 8229, Cotonou, Bénin; Faculté des sciences de la santé, université d'Abomey Calavi, Abomey Calavi, Bénin.

Context Bronchial cancer in a person under 30 years of age is quite rare. It generally occurs after 40 years of age following heavy smoking intoxication. We report a clinical case illustrating the early onset of a small cell lung carcinoma in young heavy smoker.

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Urolithiasis is a global phenomenon. Cystolithiasis is common in parts of Africa due to low protein intake and dehydration from endemic diarrhoeal illnesses. Nephrolithiasis is less prevalent than in high-income countries, probably due to a variety of lifestyle issues, such as a more elemental diet, higher physical activity, and less obesity.

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Article Synopsis
  • The study investigated severe cutaneous adverse drug reactions (SCADRs) in children at a hospital in Cotonou, focusing on their epidemiological, clinical, and etiological aspects over a 10-year period.
  • A total of 35 out of 74 pediatric cases were identified, with a mean age of 9.3 years; self-medication was a common factor in 76.5% of cases, often initiated by parents.
  • The primary severe reactions diagnosed were Steven Johnson syndrome (51.4%) and Lyell syndrome (22.8%), with penicillins and paracetamol being the most frequently involved drugs.
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Smartphone-based gait and balance assessment in survivors of stroke: a systematic review.

Disabil Rehabil Assist Technol

January 2024

Department of Kinesiology and Community Health, College of Applied Health Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

Purpose: Gait and balance impairments are associated with falls and reduced quality of life among survivors of stroke (SS). Effective methods to assess these impairments at-home and in-clinic can help reduce fall risks and improve functional outcomes. Smartphone technology may be able to evaluate these impairments.

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One of the widest variations in contemporary surgical practice between high and low, or low-middle, income countries is the utilisation of endoscopy as a means of treating urological pathology. The endoscopic management of lower urinary tract problems such as benign prostatic hypertrophy, bladder cancer and urethral strictures was established in the UK in the late 1970s, whilst its adoption into everyday practice in sub-Saharan Africa (SSA) has been significantly retarded. It is still neither a major feature of urological training in those countries nor widely available to the patients that established consultants treat.

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Introduction: Helicobacter pylori (H. pylori) infection is common in developing countries such as Benin. This germ may cause the development of gastroduodenal diseases, ranging from gastritis to gastric cancer.

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Article Synopsis
  • The rise of extended-spectrum beta-lactamase (ESBL) producing bacteria poses a significant global health threat, particularly linked to high rates of surgical site infections in developing regions with limited antibiotic options.
  • This study utilized whole-genome sequencing (WGS) on 19 ESBL-positive bacterial isolates from patients in Benin to analyze their antimicrobial resistance and genetic relationships, revealing 13 different sequence types.
  • The findings highlighted a substantial presence of ESBL resistance genes and other resistance factors, emphasizing the utility of WGS for understanding multidrug-resistant bacteria in under-researched environments.
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Introduction: hepatitis C is a public health problem worldwide, in particular in sub-Saharan Africa. The purpose of this study is to determine the seroprevalence of hepatitis C virus antibodies and associated factors during a voluntary general population screening program in Benin.

Method: we conducted a descriptive and analytical cross-sectional study in 4 big cities of 4 different departments in Benin in July 2016.

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Gait dysfunctions and balance impairments are key fall risk factors and associated with reduced quality of life in individuals with Parkinson's Disease (PD). Smartphone-based assessments show potential to increase remote monitoring of the disease. This review aimed to summarize the validity, reliability, and discriminative abilities of smartphone applications to assess gait, balance, and falls in PD.

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Purpose: To establish the epidemiological and tomographic profile of macular holes in the Beninese subject.

Patients And Methods: This cross-sectional study included consecutive patients seen for macular testing during the period from January 2016 to August 2017 at the St. Anthony of Padua Retinal Testing Center in Cotonou (Benin).

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Purpose: Investigating mothers' perceptions of Cerebral Palsy (CP) and the impact of caregiving on family life in Benin, a west-African low to middle-income country (LMIC).

Methods: In this cross-sectional study we interviewed at their homes 88 mothers of children with CP about their perception of the cause of CP and stigmatization issues. Additionally, they completed the Impact on Family Scale and the Family Support Scale questionnaires.

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