3 results match your criteria: "Centre International de Recherche en Infectiologie Lyon[Affiliation]"
Effect of SARS-CoV-2 infection and pandemic period on healthcare-associated infections acquired in intensive care units.
Clin Microbiol Infect
April 2023
REA-REZO (Surveillance, Infections & Antibiotic Resistance Network in ICU), Hospices Civils de Lyon Groupement Sud, St Genis Laval, France; Public Health, Epidemiology and Evolutionary Ecology of Infectious Diseases, Centre International de Recherche en Infectiologie Lyon, France; CPias Auvergne Rhône-Alpes, Hôpital Henry Gabrielle, Hospices Civils de Lyon, France.
Objectives: To compare the occurrence of healthcare-associated infections acquired in intensive care units (HAI-ICUs) in France among patients with COVID-19 and those without it in 2020 and the latter with that in patients before the COVID-19 pandemic.
Methods: Multicentre HAI-ICU surveillance network (REA-REZO) data were used to identify 3 groups: 2019 patients (2019Control), a COVID-19 group (2020Cov), and a non-COVID-19 group (2020NonCov). The primary outcome was the occurrence of HAI-ICU (ventilator-associated pneumonia [VAP], bloodstream infections [BSIs], catheter-related bacteraemia).
SARS-CoV-2 infection fatality rate (IFR) doubles with every five years of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ~20% of deceased patients across age groups. In the general population, they are found in ~1% of individuals aged 20-70 years and in >4% of those >70 years old.
View Article and Find Full Text PDFAn immunosuppressive pathway for tumor progression.
Nat Med
March 2018
CIRI, Centre International de Recherche en Infectiologie Lyon, France; INSERM, U1111, Lyon, France; École Normale Supérieure de Lyon, Lyon, France; Université Lyon 1, Lyon, France; and CNRS, UMR 5308, Lyon, France.