541 results match your criteria: "Centre Hospitalier Le Vinatier[Affiliation]"

Devices for the electrical stimulation of the olfactory system: A review.

Biosens Bioelectron

December 2024

Laboratory of Microsystems LMIS1, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015, Lausanne, Switzerland.

The loss of olfactory function has a profound impact on quality of life, affecting not only sensory perception but also memory, emotion, and overall well-being. Despite this, advancements in olfactory prostheses have lagged significantly behind those made for vision and hearing restoration. This review offers a comprehensive analysis of the current state of devices for electrical stimulation of the olfactory system.

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Purpose: Psychopharmacology prescriptions are complex, partly due to the complexity of the relationship between diagnosis and its etiology, as well as the iatrogenic impact on symptomatology. Many multidisciplinary tools exist to optimize their management and improve evidence-based practice. However, their multidisciplinary integration seems to be a challenge.

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Much work has investigated beneficial effects of mindfulness-based meditation methods, but less work has investigated potential risks and differences across meditation methods. We addressed this in a large pre-registered online survey including 613 mediators where we correlated participants' experience with fifty meditation techniques to psychotic-like experiences (PLEs) and mystical experiences. We found a positive correlation for both PLEs and mystical experiences with techniques aiming at reducing phenomenological content ('null-directed', NDM) or classified as non-dual or less embodied.

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[Diagnosis and management of delirium in older adults].

Rev Med Interne

November 2024

Clinical Gerontology Department, CHU of Nantes, Nantes, France.

Article Synopsis
  • * It functions like "acute brain failure," often triggered by other health problems like infections or metabolic issues, and can have serious impacts on patients and the healthcare system.
  • * The review focuses on diagnosing delirium in older adults, discussing available screening tools, exploring its relationship with dementia, and outlining both non-drug and drug management strategies for treatment.
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Impairments in facial expression recognition in patients with euthymic bipolar disorders using the facial emotions recognition test.

J Affect Disord

February 2025

Institut de Psychiatrie (CNRS GDR 3557), Paris 75000, France; Établissement public de santé mentale Barthélémy Durand, Etampes 91150, France; Université Paris-Saclay, Centre Hospitalier Kremlin-Bicêtre, 94270, France; Laboratoire de recherche PSYCOMADD, Centre Hospitalier Paul Brousse, Villejuif, 94800, France; Centre de Recherche en Epidémiologie et Santé des Populations, UMR 1018, Université Paris-Saclay, UVSQ, France.

Background: Patients with bipolar disorders (BD) have significant impairments in Facial Expression Recognition (FER), an essential social skill for effective social interactions. While the Facial Emotions Recognition Test, 54 photographs by Gaudelus (TREF-54g) has been used in patients with schizophrenia, no study has evaluated FER using this test in BD patients. The TREF-54g meets the International Society for Bipolar Disorders (ISBD) criteria for assessing FER.

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Introduction: Gynecological primary care is a public health issue, however, there is no French data on the transmasculine population, despite identified needs and a low coverage rate described in the international literature. The objective was to analyze the access of the French transmasculine population to gynecological primary care.

Methods: The study "Trans men and Transmasculine non-binary individuals use and access to prevention and sexual health care 2022" is a non-interventional, self-administrated, anonymous online study targeting transmasculine adults living in France.

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Lavender improves sleep through olfactory perception and GABAergic neurons of the central amygdala.

J Ethnopharmacol

January 2025

Departments of Neuroscience, Anatomy, Histology, and Embryology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, 730000, China. Electronic address:

Ethnopharmacological Relevance: The use of lavender as sleep aid or hypnotic agent can be traced back as early as ancient Romans and Greeks. Yet, objective experimental data on whether and how lavender enhances sleep duration or/and sleep quality remain lacking.

Aim Of The Study: We aimed to characterize the sleep-wake regulating effects of lavender in the mouse and to demonstrate the brain targets and neural circuits involved.

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Background: Nursing homes in the Caribbean are scarce and the characteristics of their residents have not been previously documented. This study aimed to describe the clinical profiles of residents living in nursing homes in Guadeloupe and Martinique (French West Indies).

Methods: This is a cross-sectional study of the baseline screening data from the KASEHPAD (Karukera Study of Ageing in nursing homes) study.

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Global Perspectives, Local Policies: The Complexities of Race and Ethnicity in Research.

J Am Acad Child Adolesc Psychiatry

September 2024

Université Claude Bernard Lyon 1, Lyon, France; Centre Hospitalier le Vinatier, Lyon, France; University College London, London, United Kingdom.

The recent article by Riccioni et al. entitled "Systematic Review and Meta-Analysis: Reporting and Representation of Race/Ethnicity in 310 Randomized Controlled Trials of Attention-Deficit/Hyperactivity Disorder Medications" highlights the gaps and disparities in the inclusion and reporting of racial and ethnic data in clinical research, using the example of research on attention-deficit/hyperactivity disorder pharmacological treatment. The authors emphasized the underreporting of data on race and ethnicity in randomized controlled trials on attention-deficit/hyperactivity disorder medications and the overrepresentation of White participants.

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[Opioid crisis in the USA: what are implications for Switzerland?].

Rev Med Suisse

September 2024

Section of addiction medicine in general internal medicine, Department of medicine, Oregon Health & Science University, 3266 SW Research Dr, Portland, Orégon 97239, États-Unis.

Warnings in Europe signal a rise in illicitly-manufactured fentanyl and other high potency synthetic opioids which could destabilize drug markets, strain health systems, and escalate harms of substance use and death. Here, we provide an overview of fentanyl in North America, drawing implications for Switzerland. Fentanyl withdrawal starts sooner, is more severe, and has worse anxiety and pain.

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Objectives: Professional foster families for dependent older adults could be an alternative to nursing homes. Engagement in the family life and close contact with a single reference person could enhance their quality of life (QOL). This study aimed to compare the Health-Related Quality of Life (HrQOL) and subjective QOL among older adults living in foster families versus those in nursing homes.

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Background: Social accountability aims to promote a collective ethic that upholds the fundamental values of equity, efficiency, solidarity, and social justice in healthcare and is now considered as a critical mission of academic health centers. Collaborative Online International Learning (COIL) is a pedagogical approach that uses digital technology to provide experiential international learning, specifically for increasingly diverse and multicultural healthcare work environments. The SOLID'AIRS program is an innovative French-language COIL that aims to set up international exchanges and workshops on social accountability between health sciences students.

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Falls are a common geriatric syndrome in older people. Falls are associated with adverse health events such as dependency, unplanned emergency admissions and death. This study aimed to identify the factors associated with fall severity, such as diabetes, hypertension, heart disease, cognitive decline and polypharmacy, as well as sociodemographic characteristics in patients aged 70 years and over admitted to the emergency department in Guadeloupe.

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Aims: This systematic review and meta-analysis aimed to assess the efficacy of NMDA antagonists in ASD (Autism Spectrum Disorder) on the core (communication and social interaction, repetitive behavior) and associated symptoms (irritability) of ASD, as well as their safety.

Methods: PubMed, CENTRAL, CINHAL, EMBASE, and PsycINFO databases were searched until November 2023. Two authors independently selected the studies and extracted data.

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Background And Objectives: Foster families for older adults could represent a transitional or alternative model to nursing homes. The aim of this study was to describe the clinical characteristics of older adults in foster families and to compare them with those of residents in nursing homes in French West Indies.

Research Design And Methods: This study is a cross-sectional analysis of the KArukera Study of Aging in Foster Families (KASAF) cohort.

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Factors influencing the implementation of parent-mediated intervention are insufficiently studied. This study examines for the first-time factors of implementation into clinical practice across the world of Pediatric Autism Communication Therapy, an internationally disseminated, evidence-based, parent-mediated therapy. From both the parents' and the professionals' perspectives, parents attitudes (e.

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Background: This study aimed to assess the prevalence of malnutrition and its determinants in older adults living in French Caribbean nursing homes.

Methods: This cross-sectional study was taken from the KASEHAD (Karukera Study of Ageing in EHPAD) study. Nutritional status was assessed with the Mini Nutritional Assessment Short-Form (MNA-SF).

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[Pain assessment for children and adolescents with autism spectrum disorders (ASD): A systematic review].

Encephale

July 2024

Faculté des sciences médicales et paramédicales, Aix-Marseille université, 13385 Marseille, France; EA3279-CEReSs, centre hospitalier d'Aix-en-Provence, 13100 Aix-en-Provence, France.

Objective: Pain in children and adolescents with autism spectrum disorders remains underdiagnosed due to their inherent communication difficulties. The goal of this review is to identify the most suitable methods for assessing pain in this population and for evaluating the specific perceptions of, or behavioural reactions to, pain whilst considering disorder severity and specifiers (with or without accompanying intellectual impairment, with or without accompanying language impairment).

Method: A systematic review and analysis of the international literature was conducted.

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Adherence to clinical practice guidelines for using electroconvulsive therapy in elderly depressive patients.

BMC Psychiatry

July 2024

French Society for Biological Psychiatry and Neuropsychopharmacology, Saint Germain en Laye, France.

Objectives: Electroconvulsive therapy (ECT) is one of the most effective treatments in mood disorders, mainly in major depressive episode (MDE) in the context of either unipolar (MDD) or bipolar disorder (BD). However, ECT remains a neglected and underused treatment. Older people are at high risk patients for the development of adverse drug reactions.

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Background: Foster families may represent an alternative model for dependent older adults in many countries where nursing homes are insufficiently developed. This study aimed to assess the prevalence of malnutrition and its determinants in older adults living in foster families in Guadeloupe (French West Indies).

Methods: This cross-sectional study was gathered from the KASAF (Karukera Study of Ageing in Foster families) study (n = 107, 41M/66F, Mdn 81.

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Comparing methadone policy and practice in France and the US: Implications for US policy reform.

Int J Drug Policy

July 2024

Service Universitaire d'Addictologie de Lyon, Centre Hospitalier Le Vinatier, Bron, France; Centre de Soins d'Accompagnement et de Prévention en Addictologie, Hospices Civils de Lyon, Lyon, France.

Despite being among the most effective treatments for opioid use disorder, methadone is largely unavailable in the United States, due primarily to federal and other policies that limit its availability and regulate clinical decisions about doses, visit frequency, and drug testing. There is unprecedented momentum to change decades-old US methadone policies. Yet uncertainty remains as to whether reforms will be adopted and how policies will be implemented.

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Prodromal or mild Alzheimer's disease: Influence of neuropsychiatric symptoms and premordid personality on caregivers' burden.

Int J Geriatr Psychiatry

June 2024

Memory Clinical and Research Center of Saint Etienne (CMRR), Neurology Unit, Hospital of Saint Etienne, Saint Etienne, France.

Article Synopsis
  • - This study explores how the premorbid personality of patients with mild Alzheimer's disease affects the burden on their caregivers, focusing on the influence of neuropsychiatric symptoms (NPS).
  • - Researchers assessed 180 individuals with early Alzheimer's using personality tests, NPS evaluations, and caregiver burden scales, finding that higher NPS scores and certain personality traits (like high neuroticism and low conscientiousness) were linked to increased caregiver burden.
  • - The findings indicate that caregivers may experience less burden when patients possess higher levels of extraversion and conscientiousness, suggesting that a patient's personality can significantly impact caregiver stress during early stages of Alzheimer's.
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Personal Income Performance Correlates with Brain Structural Network Modularity but Not Intelligence Quotient.

Brain Connect

June 2024

CREATIS, CNRS UMR 5220, INSERM U1294, Université Claude Bernard-Lyon1, INSA-Lyon, Université de Lyon, Villeurbanne, France.

This study aims to use diffusion tensor imaging (DTI) in conjunction with brain graph techniques to define brain structural connectivity and investigate its association with personal income (PI) in individuals of various ages and intelligence quotients (IQ). MRI examinations were performed on 55 male subjects (mean age: 40.1 ± 9.

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