185 results match your criteria: "Centre Hospitalier Intercommunal de Poissy - Saint-Germain[Affiliation]"

Electrical impedance tomography (EIT) is an emerging technology for the non-invasive monitoring of regional distribution of ventilation and perfusion, offering real-time and continuous data that can greatly enhance our understanding and management of various respiratory conditions and lung perfusion. Its application may be especially beneficial for critically ill mechanically ventilated patients. Despite its potential, clear evidence of clinical benefits is still lacking, in part due to a lack of standardization and transparent reporting, which is essential for ensuring reproducible research and enhancing the use of EIT for personalized mechanical ventilation.

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Chromosomal abnormalities in oocyte donor candidates: a French survey of over 8,200 karyotypes.

Fertil Steril

October 2024

CECOS et Biologie de la reproduction, Hôpital Jean Verdier, Hôpitaux Universitaires Paris Seine-Saint-Denis, AP-HP, Université Sorbonne Paris Nord, Villetaneuse, France; INSERM U1016-Equipe "Génomique, Epigénétique et Physiologie de la Reproduction," Institut Cochin, Université Paris Descartes-Paris, Paris, France.

Objective: To study karyotypes of >8,200 oocyte donor candidates in nulliparous or multiparous women compared with a reference population.

Design: A retrospective observational multicentric study.

Setting: University Hospital Centers.

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Vaginal microbiota stability over 18 months in young student women in France.

Eur J Clin Microbiol Infect Dis

December 2024

Anti-Infective Evasion and Pharmacoepidemiology Team, Université Paris-Saclay, UVSQ, Inserm, CESP, 78180, Montigny-le-Bretonneux, France.

Purpose: Non-optimal vaginal microbiota lacking lactobacilli and comprising a wide array of anaerobic bacteria, typified by community state type (CST) IV, have been associated with adverse gynecological and pregnancy outcomes. Here, we investigate the stability of the vaginal microbiota sampled every 6 months over 18 months and how samples distantly collected combined with exposures could provide insight on future microbiota compositional changes.

Methods: Vaginal microbiota dynamics were analyzed in 241 female students aged 18-24 years and negative for Chlamydia trachomatis and Neisseria gonorrhoeae.

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Introduction: Errors in reasoning are the main causes of poor decision-making in clinical practice. To remedy this, many studies highlight the importance of supervising clinical reasoning during medical internships. Although decision-making is an ongoing process at all key moments of the perioperative period, there are no studies on the supervision of clinical reasoning during student nurse anesthetist internships.

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Perinatal outcomes between immediate vs deferred selective termination in dichorionic twin pregnancies with fetal congenital anomalies: a French multicenter study.

Am J Obstet Gynecol MFM

June 2024

Service de Gynécologie-Obstétrique, Hôpital Louis-Mourier, AP-HP, Colombes, France (Drs Soussan, Egloff, Peyronnet, Mandelbrot, and Picone); Universié Paris Cité, Paris, France (Drs Soussan, Egloff, Mandelbrot, and Picone); IAME, Inserm, Paris, France (Drs Mandelbrot and Picone); FHU PREMA, Paris, France (Drs Mandelbrot and Picone).

Article Synopsis
  • A study was conducted to compare perinatal outcomes between immediate and deferred selective termination of discordant twin pregnancies with anomalies, considering the risk of pregnancy loss.
  • The results showed that the deferred selective termination group had a 100% survival rate for the healthy co-twin, while the immediate group had a 93.8% survival rate (P<.01).
  • Additionally, the rate of preterm birth was significantly lower in the deferred group (20.2%) compared to the immediate group (66.7%), indicating more favorable outcomes with delayed procedures.*
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Evaluation of Elastic Venous Compression Device dispensation in pregnant and post-partum women using the French National Health Insurance Claims Database: The ProFIL retrospective cohort study.

Eur J Obstet Gynecol Reprod Biol

May 2024

Obstetrics and Gynecology department, Centre Hospitalier Intercommunal de Poissy-Saint-Germain-en-Laye, 10 Rue du Champ Gaillard, BP 3082, 78303 Poissy CEDEX, France; Paris-Saclay university, UVSQ, research unit 7285 "Risk and safety in clinical medicine for women and perinatal health (RISCQ), 2 Avenue de la source de la Bièvre, 78180 Montigny-le-Bretonneux, France. Electronic address:

Objectives: To describe the real-world use of Elastic Venous Compression Devices (EVCDs) during pregnancy and post-partum using data from a representative subset of the French National Health Insurance Claims Database (the Echantillon Généraliste des Bénéficiaires, EGB).

Study Design: Women aged 15-49 who were pregnant between 1st July 2017 and 15th June 2018 were identified in the EGB using pregnancy-specific acts (certain prenatal examinations or deliveries). Subgroups were defined by age, presence of Venous Thrombo-Embolism (VTE) risk factors, history of VTE, delivery type and time period.

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Evaluating the satisfaction and utility of social networks in medical practice and continuing medical education.

BMC Med Educ

February 2024

UMR 1198 BREED, équipe RHuMA, UFR Simone Veil Santé, Université Versailles Saint Quentin en Yvelines, Université Paris Saclay, Paris, France.

Article Synopsis
  • * A study surveyed 1,451 members of a physician social network to evaluate the impact of these online tools on medical education.
  • * Results showed that most respondents felt they gained valuable medical knowledge and access to resources through the group, especially benefiting general practitioners and those in limited healthcare areas.
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Background: Endotracheal tube fixation in ventilated patients must be appropriate to ensure security during mechanical ventilation and prevent skin lesions. The incidence of endotracheal tube-caused pressure ulcers ranges from 7% to 45%. Various endotracheal tube fixations are used in intensive care units (ICUs) worldwide.

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COVID-19 outcomes in patients with multiple sclerosis: Understanding changes from 2020 to 2022.

Mult Scler

March 2024

Sorbonne University, Paris Brain Institute-ICM, Assistance Publique-Hôpitaux de Paris (AP-HP), Inserm, CNRS, Hôpital de la Pitié Salpêtrière, CIC Neurosciences, FCRIN4MS, Paris, France.

Background: Epidemiologic studies on coronavirus disease 2019 (COVID-19) in patients with multiple sclerosis (pwMS) have focused on the first waves of the pandemic until early 2021.

Objectives: We aimed to extend these data from the onset of the pandemic to the global coverage by vaccination in summer 2022.

Methods: This retrospective, multicenter observational study analyzed COVISEP registry data on reported COVID-19 cases in pwMS between January 2020 and July 2022.

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Article Synopsis
  • - The study aimed to evaluate patient-reported outcome measures (PROMs) for assessing sexual function in women with endometriosis, focusing on their reliability and validity to enhance research and clinical practices
  • - A systematic review from January 2000 to September 2023 examined 74 studies on sexual function in endometriosis, identifying 25 different PROMs, with the Female Sexual Function Index (FSFI) being the most used
  • - Findings revealed that key measurement properties like "hypothesis testing" and "responsiveness" were most common among PROMs, with the FSFI and Sexual Activity Questionnaire being particularly valuable for evaluating medical and surgical treatments respectively
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Electrical Impedance Tomography to Monitor Hypoxemic Respiratory Failure.

Am J Respir Crit Care Med

March 2024

Sorbonne Université, Groupe de Recherche Clinique 30, Réanimation et Soins Intensifs du Patient en Insuffisance Respiratoire Aigüe, UMRS_1166-ICAN, Institute of Cardiometabolism and Nutrition, Service de Médecine Intensive - Réanimation, Assistance Publique-Hôpitaux de Paris (APHP) Hôpital Pitié-Salpêtrière, Paris, France.

Hypoxemic respiratory failure is one of the leading causes of mortality in intensive care. Frequent assessment of individual physiological characteristics and delivery of personalized mechanical ventilation (MV) settings is a constant challenge for clinicians caring for these patients. Electrical impedance tomography (EIT) is a radiation-free bedside monitoring device that is able to assess regional lung ventilation and changes in aeration.

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Background: Women with a previous caesarean delivery face a difficult choice in their next pregnancy: planning another caesarean or attempting vaginal delivery, both of which are associated with potential maternal and perinatal complications. This trial aimed to assess whether a multifaceted intervention, which promoted person-centred decision making and best practices, would reduce the risk of major perinatal morbidity among women with one previous caesarean delivery.

Methods: We conducted an open, multicentre, cluster-randomised, controlled trial of a multifaceted 2-year intervention in 40 hospitals in Quebec among women with one previous caesarean delivery, in which hospitals were the units of randomisation and women the units of analysis.

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Medical advances now enable children with chronic illnesses to live better and longer. As a result, the transition from adolescence to adulthood is increasingly being addressed in pediatric wards, with the aim of optimizing continuity of care. This was achieved at the pediatric day hospital at the Centre hospitalier intercommunal de Poissy-Saint-Germain-en-Laye, near Paris.

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Impact of discontinuing oxytocin in active labour on neonatal morbidity: an open-label, multicentre, randomised trial.

Lancet

December 2023

Université Paris Cité, Inserm UMR 1153, Equipe EPOPé, Paris, France; Department of Obstetrics and Gynecology, Port-Royal Maternity Hospital, AP-HP, Cochin Hospital, FHU PREMA, Paris, France.

Article Synopsis
  • Oxytocin can shorten labor but may cause complications, leading researchers to investigate if stopping the drug during labor affects neonatal outcomes.
  • The STOPOXY trial, conducted in 21 French maternity units, randomly assigned participants to either stop or continue oxytocin infusion after reaching 6 cm dilation, measuring neonatal morbidity based on specific health indicators at birth.
  • The study included 2,170 eligible participants, finding no significant difference in neonatal morbidity between the two groups, suggesting that discontinuing oxytocin may not increase risks for newborns.
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[Vaginal laxity: Semiology, diagnosis and treatments].

Gynecol Obstet Fertil Senol

February 2024

Service de gynécologie-obstétrique, centre hospitalier Intercommunal de Poissy-Saint-Germain-en-Laye, 10, rue du champ Gaillard, 78303 Poissy cedex, France; Unité de recherche 7285 « Risques cliniques et sécurité en santé des femmes et en santé périnatale »(RISCQ), UVSQ, université Paris-Saclay, 78180 Montigny-le-Bretonneux, France.

Objectives: Vaginal laxity concerns 24 to 38% of women but it's still poorly understood and studied. The objective of this study is to do an inventory of current scientific knowledge about its definition, its diagnostic criteria, and treatments.

Methods: We conducted a non systematic review of literature including original articles in French and English about the definition, diagnostic criteria and treatments of vaginal laxity using data bases such as Cochrane, Embase, Medline, PubMed et Science Direct.

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Developing a set of patient-centered outcomes for routine use in endometriosis: An international Delphi study.

Acta Obstet Gynecol Scand

January 2024

Research Unit 7285 Clinical Risks and Safety in Women's Health and Perinatal Health (RISCQ), UVSQ, Université Paris-Saclay, Montigny-le-Bretonneux, France.

Article Synopsis
  • - The study aims to create a standardized set of patient-centered outcomes for treating endometriosis, enhancing personalized care and monitoring treatment effectiveness.
  • - Using a modified Delphi method, 51 participants from 16 countries evaluated numerous Patient Reported Outcome Measures (PROMs) and Clinician Reported Outcome Measures (CROMs) to establish relevant metrics for routine care.
  • - The final outcomes include six PROMs focused on symptoms, pain, productivity, and quality of life, alongside ten CROMs covering clinical indicators; additional tools are also suggested for assessing psychological and sexual impacts of endometriosis.
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SPLF/SMFU/SRLF/SFAR/SFCTCV Guidelines for the management of patients with primary spontaneous pneumothorax.

Ann Intensive Care

September 2023

Pôle Urgences, Centre Hospitalier du Forez, & Groupement de Coopération Sanitaire Urgences-ARA, Av. des Monts du Soir, 42600, Montbrison, France.

Introduction: Primary spontaneous pneumothorax (PSP) is the presence of air in the pleural space, occurring in the absence of trauma and known lung disease. Standardized expert guidelines on PSP are needed due to the variety of diagnostic methods, therapeutic strategies and medical and surgical disciplines involved in its management.

Methods: Literature review, analysis of the literature according to the GRADE (Grading of Recommendation, Assessment, Development and Evaluation) methodology; proposals for guidelines rated by experts, patients and organizers to reach a consensus.

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Perceived Quality of Life in Intensive Care Medicine Physicians: A French National Survey.

J Intensive Care Med

March 2024

Laboratoire de Psychologie : Dynamiques Relationnelles et Processus Identitaires (PsyDREPI), Université de Bourgogne Franche-Comté, Dijon, France.

There is a growing interest in the quality of work life (QWL) of healthcare professionals and staff well-being. We decided to measure the perceived QWL of ICU physicians and the factors that could influence their perception. We performed a survey coordinated and executed by the French Trade Union of Intensive Care Physicians (SMR).

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FX06 to rescue SARS-CoV-2-induced acute respiratory distress syndrome: a randomized clinical trial.

Crit Care

August 2023

Service de Médecine Intensive-Réanimation, Institut de Cardiologie, Assistance Publique-Hôpitaux de Paris (APHP), Hôpital Pitié-Salpêtrière, Paris, France.

Article Synopsis
  • Vascular leakage is a key issue in ARDS, especially in COVID-19 patients, and the study aimed to test FX06, a drug meant to stabilize blood vessel junctions, for its effectiveness in reducing this leakage.
  • In a double-blinded trial with 49 adults on mechanical ventilation, participants received either FX06 or a placebo, but results showed no difference in lung-water levels or other key measures between the two groups after 7 days.
  • Although FX06 did not reduce vascular leakage, it was associated with a higher incidence of ventilator-associated pneumonia, indicating the need for further studies to assess its timing and dosing for better results.
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Importance: Considering the lack of equipoise regarding the timing of cholecystectomy in patients with moderately severe and severe acute biliary pancreatitis (ABP), it is critical to assess this issue.

Objective: To assess the outcomes of early cholecystectomy (EC) in patients with moderately severe and severe ABP.

Design, Settings, And Participants: This cohort study retrospectively analyzed real-life data from the MANCTRA-1 (Compliance With Evidence-Based Clinical Guidelines in the Management of Acute Biliary Pancreatitis) data set, assessing 5304 consecutive patients hospitalized between January 1, 2019, and December 31, 2020, for ABP from 42 countries.

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Moderate or intensive management of the active phase of second-stage labor and risk of urinary and anal incontinence: results of the PASST randomized controlled trial.

Am J Obstet Gynecol

November 2023

Université Paris Cité, Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité (CRESS), Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Institut national de la santé et de la recherche médicale (Inserm), Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (INRAE), Paris, France; AP-HP, Maternity Port Royal, FHU PREMA, Paris, France.

Background: Incontinence occurs frequently in the postpartum period. Several theoretical pathophysiological models may underlie the hypothesis that different types of management of the active phase of the second stage of labor have different effects on pelvic floor muscles and thus perhaps affect urinary and anal continence.

Objective: This study aimed to evaluate the impact of "moderate pushing" on the occurrence of urinary or anal incontinence compared with "intensive pushing," and to determine the factors associated with incontinence at 6 months postpartum.

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