23 results match your criteria: "Centre Hospitalier Général de Bourges.[Affiliation]"

Introduction: First-line oxygenation strategy in patients with acute hypoxaemic respiratory failure consists in standard oxygen or high-flow nasal oxygen therapy. Clinical practice guidelines suggest the use of high-flow nasal oxygen rather than standard oxygen. However, findings remain contradictory with a low level of certainty.

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  • A study examined the prevalence of PTSD among ICU survivors after being treated for COVID-19 compared to other causes of ICU admission, finding that 4.9% of patients in both groups had a presumptive diagnosis of PTSD six months later.
  • After adjusting for factors like age and prior trauma, COVID-19 status alone was not linked to PTSD diagnosis, although female patients were more likely to exhibit PTSD symptoms.
  • Patients treated for COVID-19 did report higher levels of specific PTSD symptoms like intrusion and avoidance when compared to those treated for other conditions, indicating different psychological impacts.
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Context: The use of vagus nerve stimulation (VNS) to reduce or stop electroconvulsive therapy (ECT) in treatment-resistant depression seems promising. The aim of this study was to investigate the efficacy of VNS on the reduction of ECT sessions and mood stabilization.

Methods: We conducted a monocentric retrospective case series of patients who suffered from treatment-resistant depression, treated with ECT and referred to our center for VNS.

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  • The study examines the effectiveness of high-flow nasal cannula oxygen compared to standard oxygen in reducing mortality and the need for intubation in COVID-19 patients experiencing respiratory failure in ICUs.
  • Conducted across 34 ICUs in France, the SOHO-COVID trial involved 711 patients, randomly assigned to receive either high-flow oxygen or standard oxygen.
  • Results showed no significant difference in mortality rates at day 28 between the two groups, with 10% mortality for high-flow and 11% for standard oxygen, suggesting both methods are similarly effective.
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  • The study examines the relationship between first medical contact-to-balloon time and 1-year mortality in patients with ST-elevation myocardial infarction (STEMI), focusing on the effects of direct vs. indirect transfer to cardiac catheterization laboratories (CCLs).
  • Out of 2,206 STEMI patients, those indirectly admitted to CCL had a higher mortality rate (14.6%) compared to direct admissions (7.7%), highlighting that indirect admissions correlate with worse outcomes despite similar FMC-to-balloon times.
  • Key factors influencing indirect admission included older age and the type of initial medical contact (like paramedic response), indicating a need for better population education and care coordination, especially for elderly
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Impact of the first lockdown for coronavirus 19 on breast cancer management in France: A multicentre survey.

J Gynecol Obstet Hum Reprod

November 2021

Department of Gynaecology, Centre Hospitalier Universitaire de Tours, Tours, France; INSERM U1069 Université François-Rabelais, Tours, France. Electronic address:

Objective: This study examined the impact of lockdown for SARS-CoV-2 on breast cancer management via an online survey in a French multicentre setting.

Material And Methods: This is a multicentre retrospective study, over the strict lockdown period from March 16th to May 11th, 2020 in metropolitan France. 20 centres were solicited, of which 12 responded to the survey.

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Growing use of fractional flow reserve (FFR) and intracoronary imaging techniques by optical coherence tomography or intravascular ultrasound has raised concerns about additional exposure during coronary angiography and percutaneous coronary interventions (PCIs). Using data from the prospective CRAC-France PCI Prospective Multicentre registry, we sought to evaluate the effect of these new techniques on the radiation dose to patients undergoing coronary procedures. Data on Kerma Area Product (PKA), total air kerma (KAr) and fluoroscopy time from 42 182 coronary procedures were retrospectively compared, using multivariable linear regression, according to whether they included FFR and intracoronary imaging.

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  • STEMI patients with multivessel disease (MVD) generally have a worse prognosis, but recent studies suggest this gap might have narrowed with improved treatment.
  • The study analyzed 1,886 STEMI patients who received timely primary PCI to compare outcomes based on the number of diseased vessels (one-, two-, and three-vessel disease).
  • Results indicated that at one year, the rates of major adverse cardiovascular events (MACE) were similar across different vessel disease groups, suggesting that the prognosis for MVD patients may not be as poor as previously thought in modern medical settings.
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Aims: The aim of this study was to analyse delays in emergency medical system transfer of ST-segment elevation myocardial infarction (STEMI) patients to percutaneous coronary intervention (PCI) centres according to transport modality in a rural French region.

Methods And Results: Data from the prospective multicentre CRAC / France PCI registry were analysed for 1911 STEMI patients: 410 transferred by helicopter and 1501 by ground transport. The primary endpoint was the percentage of transfers with first medical contact to primary percutaneous coronary intervention within the 90 minutes recommended in guidelines.

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Background: It is critical to minimize the time between the first medical contact and primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction.

Aims: To identify factors associated with a delay of>120min between first medical contact and primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction.

Methods: Data were analysed from a regional French registry of patients undergoing coronary angioplasty for ST-segment elevation myocardial infarction<24h after symptom onset.

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[Distinctive tabard: A solution to avoid work interruptions in the blood transfusion?].

Transfus Clin Biol

November 2019

Cellule hémovigilance, agence régionale de santé, centre Val-de-Loire, 131, rue du Faubourg-Bannier BP 74409 , 45044 Orleans, France. Electronic address:

Aim: In the blood transfusion, the interruption of work (IW) can lead to serious incidents and/or adverse effects. The aim of our work is to evaluate the wearing of a distinctive tabard in the IW.

Methods: Several voluntary departments from 5 establishments of health in the Center-Val de Loire region have participated in this work from October to December 2017.

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[Non-ST elevation acute coronary syndrome: CRAC register experience].

Ann Cardiol Angeiol (Paris)

December 2018

Service de cardiologie, les hôpitaux de Chartres, Chartres, France. Electronic address:

Purpose: To compare the clinical, angiographic, therapeutic and prognostic characteristics of nonagenarians presenting with non-ST elevation acute coronary syndrome with those of patients under 90 years of age.

Methods: We used the CRAC register database including 6 catheterization laboratories in the Center Val-de-Loire region. Only patients with positive-troponin non-ST elevation ACS included in the registry from 2014 to 2017 were selected for epidemiological and procedural data.

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The CRAC cohort model: A computerized low cost registry of interventional cardiology with daily update and long-term follow-up.

Rev Epidemiol Sante Publique

May 2018

Unité régionale d'épidémiologie hospitalière (UREH), 37000 Tours, France; Université de Tours, faculté de médecine, 37000 Tours, France. Electronic address:

Objectives: To assess the reliability and low cost of a computerized interventional cardiology (IC) registry to prospectively and systematically collect high-quality data for all consecutive coronary patients referred for coronary angiogram or/and coronary angioplasty.

Background: Rigorous clinical practice assessment is a key factor to improve prognosis in IC. A prospective and permanent registry could achieve this goal but, presumably, at high cost and low level of data quality.

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18F-FDG PET/CT as a central tool in the shift from chronic Q fever to Coxiella burnetii persistent focalized infection: A consecutive case series.

Medicine (Baltimore)

August 2016

Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, Faculté de Médecine, CNRS UMR 7278, IRD 198, Aix-Marseille Université, 27 Bd Jean Moulin Service de médecine nucléaire, Hôpital de La Timone, Marseille Service de pathologies infectieuses et tropicales de l'hôpital de Nimes Service de médecine, Hôpital de Chatellerault Unité Nord Insuffisance cardiaque et valvulopathies (UNIV), Service de cardiologie CHU de Marseille, Hôpital Nord, AP-HM Chemin des Bourrely, Marseille Service de Pathologies infectieuses et tropicales, CHU de Poitiers Service de Médecine interne Hôpital de Gap Service de Médecine interne, hôpital Saint Luc, Lyon Service de Rhumatologie, Centre hospitalier de Vienne Service de Pathologies infectieuses et tropicales, CHU de Rouen Service de Pathologies infectieuses et tropicales, CHU de Tours Service de Médecine Interne, CH de Bourges Service de Médecine Interne, Hôpital Saint-Anne, Toulon Service mobile d'Infectiologie, CH Victor Dupouy, Argenteuil Service de Médecine interne, CHU de Nantes, France.

Article Synopsis
  • Q fever diagnosis is often challenging due to its reliance on serological tests, but F-FDG PET/CT offers a promising way to identify persistent infections of Coxiella burnetii.
  • In a study of 167 patients who underwent F-FDG PET/CT from 2009 to 2015, 59% showed a hypermetabolic focus, leading to revised diagnoses for 63% of those tested.
  • The study noted various infection sites, including valvular, vascular, osteoarticular, and lymphadenitis, confirming F-FDG PET/CT as a valuable diagnostic tool and suggesting new diagnostic criteria for persistent infections.
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Treatment of drug-eluting stents in-stent restenosis with paclitaxel-coated balloon angioplasty: Insights from the French "real-world" prospective GARO Registry.

Int J Cardiol

January 2016

CHU Rennes, Service de Cardiologie et Maladies Vasculaires, Rennes, F-35000, France; INSERM, U1099, Rennes, F-35000, France; Université de Rennes 1, LTSI, Rennes, F-35000, France. Electronic address:

Background: Data about paclitaxel-eluting balloon (PCB) angioplasty to treat drug-eluting stents (DES) in-stent restenosis (ISR) were mainly collected in selected patient populations in the setting of randomized trials. The main goal of this prospective registry was to confirm the positive findings of these studies in an unselected population in clinical practice.

Methods: Consecutive patients with DES-ISR treated by PCB angioplasty were recruited in this prospective real-world registry.

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Acute stent thrombosis after primary percutaneous coronary intervention: insights from the EUROMAX trial (European Ambulance Acute Coronary Syndrome Angiography).

JACC Cardiovasc Interv

January 2015

Université Paris-Diderot, Sorbonne Paris-Cité, Paris, France; Cardiology, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris, France; Institut National de la Santé et de la Recherche Médicale U1148, Paris, France; National Heart and Lung Institute, Imperial College, Imperial College School of Medicine, Royal Brompton Hospital, London, United Kingdom.

Objectives: This study sought to determine clinical, procedural, and treatment factors associated with acute stent thrombosis (AST) in the EUROMAX (European Ambulance Acute Coronary Syndrome Angiography) trial.

Background: Bivalirudin started during transport for primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction significantly reduced major bleeding compared with heparin with or without glycoprotein IIb/IIIa inhibitors (GPI), but it was associated with an increase in AST.

Methods: We compared patients with (n = 12) or without AST (n = 2,184) regarding baseline, clinical, and procedural characteristics and antithrombotic treatment strategies (choice of P2Y12 inhibitor, post-primary PCI bivalirudin infusion dose [0.

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The authors report a case of xanthogranulomatous pyelonephritis complicated by renocolic fistula. This is a rare complication. The patient was treated by right nephrectomy and closure of the fistula performed by manually assisted laparoscopic surgery.

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[Transcaval ureter].

Prog Urol

June 2002

Service d'Urologie, Centre Hospitalier de Bourges, 145, avenue François Mitterrand, BP 603, 18016 Bourges.

The authors report a case of transcaval ureter complicated by acute obstructive pyelonephritis in a 54-year-old patient. Transcaval ureter is a rare congenital malformation of the infra-renal inferior vena cava (IRIVC) in which the right ureter passes through a venous ring composed of localized duplication of the vena cava due to persistence of the right posterior cardinal and supracardinal veins.

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The authors report the case of a 40-year-old woman who presented with very large right renal varices. Computed tomography and arteriography showed that these varices were situated on the convex surface of the kidney, in front of its anterior surface, and drained venous blood derived from the renal parenchyma. These varices were probably secondary to undiagnosed renal vein thrombosis.

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Authors report on a case of emphysematous pyelonephritis in a woman affected with diabetes and renal failure. In order to avoid chronic dialysis, no nephrectomy was performed and the patient was treated only with drugs. Full recovery was obtained, without worsening of the renal function.

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The authors report a case of pelvic actinomycosis causing ureteral obstruction in a 30-year-old woman. An intra-uterine device being in place for 6 years is considered as the main cause. The treatment, which included a laparotomy for abscess drainage, an indwelling double pigtail ureteral stent and a 9 month antibiotherapy led to recovery after an initial relapse.

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The authors report the exceptionally rare case of a huge myofibroma of the round ligament. The localization of the myoma was very unusual. It developed from the inguinal insertion of the round ligament; and the fibroma had grown in the abdominal wall between muscle and the peritoneum.

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