1 results match your criteria: "Centre CEBIM[Affiliation]"
Bromination of eudesmin isolated from induces epimerization and give bromine derivatives with loss of anti-Candida activity.
Nat Prod Res
July 2023
Laboratory of Natural Products & Drug Discovery, Centre CEBIM, Universidad de La Frontera, Temuco, Chile.
Article Synopsis
- Furofuran lignanes, found in various plants, have potential benefits for treating infectious, inflammatory, and metabolic diseases.
- In Chile, specific compounds such as eudesmin and others are produced by a native conifer and can be extracted using a simpler Soxhlet method instead of traditional chromatography.
- The study found that eudesmin exhibits moderate antibacterial activity against yeast, while its altered forms (epieudesmin and brominated derivatives) show reduced or no activity.