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344 results match your criteria: "Central University Hospital of Asturias[Affiliation]"
Clin Exp Rheumatol
December 2024
Rheumatology Division, Central University Hospital of Asturias, Oviedo; Department of Medicine, Oviedo University School of Medicine, Oviedo; and Translational Immunology Division, Biohealth Research Institute of the Principality of Asturias (ISPA), Oviedo, Spain.
Objectives: Inflammatory biomarkers such as C-reactive protein (CRP) lack discriminatory capacity to detect active disease in psoriatic arthritis (PsA). Our aim was to find CRP thresholds capable of discriminating active disease in both early and established PsA.
Methods: We included a total of 345 PsA patients (215 early-onset not exposed to high-impact therapies and 130 with established disease under biologics and oral targeted therapies).
Rev Esp Med Nucl Imagen Mol (Engl Ed)
December 2024
Department of Nuclear Medicine, Gurutzeta-Cruces University Hospital/Biocruces Health Research Institute, Barakaldo, Spain.
Purpose: The main objectives were to study differences between the first and the fourth cycle in dosimetry variables in patients treated for neuroendocrine tumours with four cycles of [Lu]Lu-DOTA-TATE, as well as to look for absorbed dose-effect correlations aiming to help individualise and optimise this therapy for future patients.
Material And Methods: SPECT based dosimetry of tumour lesions and kidneys was performed in the first and the fourth cycles of the [Lu]Lu-DOTA-TATE treatments for 17 patients from 2020 to 2023. Clinical variables of interest were collected in order to look for correlations with some dosimetry variables.
Eur Geriatr Med
December 2024
Geriatrics Department, Geriatrics Clinical Management Area, Monte Naranco Hospital-Central University Hospital of Asturias, Avenida Doctores Fernández Vega, 107, 33012, Oviedo, Asturias, Spain.
Enferm Infecc Microbiol Clin (Engl Ed)
December 2024
Pulmonology Service, Cruces University Hospital (OSI EEC), Barakaldo, Spain; BioBizkaia Health Research Institute, Spain.
The Spanish Society of Pneumology and Thoracic Surgery (SEPAR) and the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) have developed together Clinical Practice Guidelines (GPC) on the management of people affected by tuberculosis (TB) resistant to drugs with activity against Mycobacterium tuberculosis. These clinical practice guidelines include the latest updates of the SEPAR regulations for the diagnosis and treatment of drug-resistant TB from 2017 to 2020 as the starting point. The methodology included asking relevant clinical questions based on PICO methodology, a literature search focusing on each question, and a systematic and comprehensive evaluation of the evidence, with a summary of this evidence for each question.
View Article and Find Full Text PDFJ Clin Med
November 2024
Rheumatology Division, Central University Hospital of Asturias, 33011 Oviedo, Spain.
Obesity and smoking have been related to increased disease activity in axial spondyloarthritis (axSpA), but these associations might vary depending on the composite index chosen to assess disease activity. We aimed to check this possibility. Three hundred and thirty consecutive patients were recruited from the monographic axSpA unit of a university center.
View Article and Find Full Text PDFNutrients
November 2024
Centro de Investigaciónn Biomedica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, 28029 Madrid, Spain.
: Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) increases the risk of Type-2 Diabetes (T2DM). The Mediterranean diet (MD) has shown advantages in the management of MAFLD and preventing co-morbidities; however, its relationship with T2DM development in MAFLD has been less investigated. We aimed to evaluate the association of MD adherence with the risk of incident T2DM in the Spanish adult population with MAFLD and according to their weight gain at 7.
View Article and Find Full Text PDFJ Infus Nurs
November 2024
Author Affiliations: Navarra's Health Research Institute (IdiSNA), Pamplona, Navarra, Spain ; Public University of Navarre, Pamplona, Spain ; University Hospital of Navarra, Pamplona, Spain ; Central University Hospital of Asturias, Asturias, Spain.
Studies have not demonstrated the effectiveness of the different types of dressings in reducing the rate of complications. The purpose of this study was to determine which type of dressing is most beneficial in reducing the rate of complications. A total of 281 patients requiring a peripheral intravenous catheter were randomized to receive partially reinforced dressings or fully reinforced dressings (dressings with integral catheter securement).
View Article and Find Full Text PDFJ Agric Food Chem
November 2024
Department of Functional Biology, University of Oviedo, Oviedo 33006, Spain.
Biomedicines
September 2024
Rheumatology Division, Central University Hospital of Asturias, 33011 Oviedo, Spain.
Background/objectives: In recent years, a possible connection between HLA-Cw6 and a distinctive cardiometabolic (CM) profile in patients with psoriatic disease (PsD) has been proposed, although there is still little support for this. Our aim was to further investigate this possible association by studying a large population of PsD patients.
Methods: For this study, three different cohorts of patients with PsD were analyzed: two with a majority of cutaneous psoriasis, pooled n: 600, and a third with only psoriatic arthritis-PsA-cases, n: 340.
Case Rep Endocrinol
October 2024
Department of Endocrinology and Nutrition, Central University Hospital of Asturias/University of Oviedo, Oviedo, Spain.
Int J Mol Sci
October 2024
Institute of Health Research of the Principality of Asturias (ISPA), 33011 Oviedo, Spain.
The gut microbiota is a key and primary stimulus for the development of a host's immune system. The early establishment of the gut microbiota is affected by several perinatal factors but little is known about their influence on shaping normal immune development and, consequently, on the programming of future health. The analysis of different immune compounds is well-documented in serum samples; however, their presence in faecal samples has not been studied, and this information could be valuable in early life.
View Article and Find Full Text PDFRev Esp Med Nucl Imagen Mol (Engl Ed)
September 2024
Department of Nuclear Medicine, Hospital Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.
Front Oncol
September 2024
Department of Otorhinolaryngology and Head and Neck Surgery, Central University Hospital of Asturias, Oviedo, Spain.
J Nucl Cardiol
September 2024
Department of Nuclear Medicine, Central University Hospital of Asturias, Oviedo, Spain.
Postepy Dermatol Alergol
August 2024
Dermatoloy Department, Marqués de Valdecilla University Hospital, Cantabria, Spain.
J Clin Med
August 2024
Department of Obstetrics and Gynecology and Neonatology, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.
Breast cancer (BC) recurrence, defined as the reappearance of cancer in the ipsilateral breast after primary treatment, poses significant challenges in clinical management. Despite advances in treatment, recurrence rates persist, ranging from 0.6 to 1.
View Article and Find Full Text PDFLancet Respir Med
October 2024
Pneumology Department, Bellvitge University Hospital, University of Barcelona, Bellvitge Biomedical Research Institute, Network Research Center for Respiratory Diseases, Barcelona, Spain.
Eur Geriatr Med
December 2024
Geriatrics Department, Geriatrics Clinical Management Area, Monte Naranco Hospital-Central University Hospital of Asturias, Avenida Doctores Fernández Vega, 107, 33012, Oviedo, Asturias, Spain.
Background: Muscle ultrasound is increasingly popular thanks to its advantages over other techniques. However, its usefulness in the diagnosis of sarcopenia in older adults with aortic stenosis (AS) has not been studied to date.
Objectives: to analyze the prevalence of sarcopenia using muscle ultrasound and its impact on the health outcomes in older patients with AS.
Sci Rep
August 2024
Molecular Imaging Group, Instituto de Investigación Sanitaria (IDIS), Santiago de Compostela, Spain.
The ability of F-FDG positron emission tomography (PET) to track disease activity and treatment response in patients with Ankylosing Spondylitis (AS) or Psoriatic Arthritis (PsA) remains unclear. Here, we assessed whether F-FDG uptake is a marker of disease activity and treatment response in AS or PsA, and explored the ability of F-FDG to predict treatment response. Patients with AS (n = 16) or PsA (n = 8) who were scheduled to initiate treatment with biologics were recruited.
View Article and Find Full Text PDFEur Heart J Cardiovasc Imaging
November 2024
Department of Cardiology, Québec Heart and Lung Institute, Laval University, Québec City, Québec G1V-4G5, Canada.
Anal Bioanal Chem
October 2024
Department of Physical and Analytical Chemistry, University of Oviedo, Julián Clavería 8, 33006, Oviedo, Spain.
During the last years, there has been an increasing research interest in the analysis of biological fluids requiring non-invasive sampling for biomedical and clinical applications. In this work, we have focused on the nasal exudate with the aim of investigating the potential use of this fluid to know the role of iron in stroke and also for diagnosis. Potential differences in the nasal exudate, collected in swabs, from diagnosed hemorrhagic stroke, ischemic stroke, and control groups were investigated with regard to total iron by inductively coupled plasma-mass spectrometry, iron fractionation studies by size exclusion chromatography together with post-column isotope dilution analysis, and four proteins containing iron (ferritin, transferrin, lactoferrin, and ferroportin) with ELISA kits.
View Article and Find Full Text PDFActa Neurochir (Wien)
August 2024
Department of Neurosurgery, Central University Hospital of Asturias, Oviedo, Principado de Asturias, Spain.
Sex Transm Infect
November 2024
Sexually Transmitted Infections Study Group (GEITS), Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), Madrid, Spain
Open Respir Arch
June 2024
Pneumology Department, Central University Hospital of Asturias, Oviedo, Spain.
Nutrients
June 2024
Department of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), 33300 Villaviciosa, Spain.
The correct initial colonization and establishment of the gut microbiota during the early stages of life is a key step, with long-lasting consequences throughout the entire lifespan of the individual. This process is affected by several perinatal factors; among them, feeding mode is known to have a critical role. Breastfeeding is the optimal nutrition for neonates; however, it is not always possible, especially in cases of prematurity or early pathology.
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