Improvement in optical properties of CsPbBr nanocrystals using aprotic polar purification solvent.

We demonstrate the influence mechanism on the optical property of CsPbBr during purification of solution with different protonated levels and polarities. During the purification process, organic groups originating from oleic acid (OA) and PbBr impurity on the surface of CsPbBr nanocrystals can be removed using high polarity aprotic and protonic solvents, and the number of Br vacancies ( ) can be reduced. The protonic polar solvent can not only etch the organic groups on the surface of nanocrystals, causing surface reconstruction and particle growth of nanocrystals, but also enter into the lattice of CsPbBr and react with the embedded CsPbBr.

Construction of a lysosome-targetable ratiometric fluorescent probe for HO tracing and imaging in living cells and an inflamed model.

Hydrogen peroxide (HO), an important reactive oxygen species (ROS) with unique destructive oxidation properties, can be produced in lysosomes to fight off pathogens. Although many fluorescent probes have been developed for the detection and imaging of HO, the development of a ratiometric fluorescent probe for HO detection and imaging in lysosomes and an inflammation model remains rather scarce. Therefore, it is important to develop an efficient tool for monitoring HO in inflamed tissues to evaluate the physiological and pathological relationship between inflammation and lysosomal HO.

Epoxy composite with high thermal conductivity by constructing 3D-oriented carbon fiber and BN network structure.

As electronic devices tend to be integrated and high-powered, thermal conductivity is regarded as the crucial parameter of electronic components, which has become the main factor that limits the operating speed and service lifetime of electronic devices. However, constructing continuous thermal conductive paths for low content particle fillers and reducing interface thermal resistance between fillers and matrix are still two challenging issues for the preparation of thermally conductive composites. In this study, 3D-oriented carbon fiber (CF) thermal network structures filled with boron nitride flakes (BN) as thermal conductive bridges were successfully constructed.

Ligand and adjuvant dual-assisted synthesis of highly luminescent and stable CsPbBr nanoparticles used in LEDs.

We developed a new ligand and adjuvant dual-assisted room temperature colloidal method for the synthesis of highly luminescent and stable CsPbBr nanoparticles, in which acetone, oleamine (OM) and oleic acid (OA) were used as precursors, while water and dimethyl sulfoxide (DMSO) were used as adjuvants. In this process, we explored the influencing factors of process parameters (such as the amount of water, the standing time of precursors, and the molar ratio of raw materials), and found that CsPbBr synthesized by water + DMSO can not only change the morphology and promote crystallization but also improve the lattice strain, reduce the lattice defects and optimize the passivation effect, so as to improve the luminescence properties. Simultaneously, we also found that the pc-LED made of CsPbBr can still emit bright green light after 4344 h of operation, showing excellent stability and making it promising for solid-state lighting application.

Enhanced phosphate removal with fine activated alumina synthesized from a sodium aluminate solution: performance and mechanism.

Fine activated alumina (FAA) acting as an adsorbent for phosphate was synthesized from an industrial sodium aluminate solution based on phase evolution from Al(OH) and NHAl(OH)CO. This material was obtained in the form of γ-AlO with an open mesoporous structure and a specific surface area of 648.02 m g.

Bromination and increasing the molecular conjugation length of the non-fullerene small-molecule acceptor based on benzotriazole for efficient organic photovoltaics.

Two novel non-fullerene acceptors, namely BZIC-2Br and Y9-2Br, were synthesized by employing a ladder-type electron-deficient-based fused ring central with a benzotriazole core. Y9-2Br is obtained by extending the conjugate length of BZIC-2Br. Compared with BZIC-2Br, Y9-2Br possesses a lower optical bandgap of 1.

Hydrogen solubility and diffusivity at Σ3 grain boundary of PdCu.

First principles calculations have been performed to comparatively reveal hydrogen solubility and diffusivity at grain boundaries of BCC and FCC PdCu phases. It is found that the temperature-dependent hydrogen solubility at BCC Σ3 (112) GB of PdCu seems much higher than that in BCC PdCu bulk, while hydrogen solubility in FCC Σ3 (111) GB of PdCu is much lower than that in its corresponding FCC bulk. Calculations also reveal that grain boundary has an important effect on hydrogen diffusion of BCC and FCC PdCu, , hydrogen diffusivities of BCC Σ3 (112) and FCC Σ3 (111) grain boundaries of PdCu seem much smaller and bigger than those of its corresponding bulks, respectively.

Specific nursing improves postoperative urine control function and the self-efficacy of patients undergoing radical prostatectomies.

Background: Radical prostatectomy is a treatment for prostate cancer (PC), but most patients suffer urinary incontinence, decreased urinary control function, and poor prognoses after the surgery. Specific nursing intervention is a nursing model based on the patients' individual conditions and disease progression.

Objective: To investigate the effects of specific nursing intervention on the urinary control functions and self-efficacy of radical prostatectomy patients.

Light responsive nucleic acid for biomedical application.

Nucleic acids are widely used in biomedical applications because of their programmability and biocompatibility. The light responsive nucleic acids have attracted wide attention due to their remote control and high spatiotemporal resolution. In this review, we summarized the latest developments in biomedicine of light responsive molecules.

Rh(ii)-catalyzed enantioselective intramolecular Büchner reaction and aromatic substitution of donor-donor carbenes.

The chiral dirhodium(ii) tetracarboxylate-catalyzed enantioselective intramolecular Büchner reaction of donor/donor-carbenes was reported and a series of valuable chiral polycyclic products were synthesized. Both aryloxy enynones and diazo compounds were efficient carbene precursors for this reaction. Excellent yields (up to 99%) and outstanding enantioselectivities (up to >99% ee) were achieved under standard conditions.

Pars plana vitrectomy assisted by intravitreal injection of conbercept enhances the therapeutic effect and quality of life in patients with severe proliferative diabetic retinopathy.

Objective: To explore the application value of intravitreal injection of Conbercept (IVC)-assisted pars plana vitrectomy (PPV) in patients with severe proliferative diabetic retinopathy (PDR).

Methods: Forty-eight patients with severe PDR who underwent surgical treatment in Chongqing Aier Eye Hospital between October 2019 and June 2021 were retrospectively enrolled, and their clinical data were analyzed. Of them, 22 patients receiving PPV alone were assigned to the PPV group, and the remaining 26 patients treated with IVC-assisted PPV were included in the PPV+IVC group.

Establishment and validation of prognostic nomograms to predict the overall and cancer-specific survival in patients with hepatic malignant vascular tumors.

Objective: To characterize the clinicopathologic features and to investigate the prognostic nomograms for overall survival (OS) and cancer-specific survival (CSS) in patients with Hepatic malignant vascular tumors (HMVT).

Method: Patients diagnosed with HMVT between 1973 and 2015 were screened from the Surveillance, Epidemiology, and End Results (SEER) database. The Kaplan-Meier (KM) was used for survival analysis.

Socioeconomic deprivation and survival outcomes in patients with colorectal cancer.

Socioeconomic deprivation has been linked to detrimental healthcare outcomes. We sought to examine whether patients with colorectal cancer (CRC) from socioeconomically disadvantaged areas experience worse survival outcomes and how it interacts with other factors. In this population-based study, patients with CRC diagnosed between 2007 to 2015 in the SEER program were reviewed.

The novel BET degrader, QCA570, is highly active against the growth of human NSCLC cells and synergizes with osimertinib in suppressing osimertinib-resistant EGFR-mutant NSCLC cells.

Lung cancer remains the leading cause of cancer deaths worldwide despite advances in knowledge in cancer biology and options of various targeted therapies. Efforts in identifying innovative and effective therapies are still highly appreciated. Targeting bromodomain and extra terminal (BET) proteins that function as epigenetic readers and master transcription coactivators is now a potential cancer therapeutic strategy.

Synergetic stability enhancement with magnesium and calcium ion substitution for Ni/Mn-based P2-type sodium-ion battery cathodes.

The conventional P2-type cathode material NaNiMnO suffers from an irreversible P2-O2 phase transition and serious capacity fading during cycling. Here, we successfully carry out magnesium and calcium ion doping into the transition-metal layers (TM layers) and the alkali-metal layers (AM layers), respectively, of NaNiMnO. Both Mg and Ca doping can reduce O-type stacking in the high-voltage region, leading to enhanced cycling endurance, however, this is associated with a decrease in capacity.

Carboplatin-loaded surface modified-PLGA nanoparticles confer sustained inhibitory effect against retinoblastoma cell in vitro.

Purpose: To investigate the antiproliferative effect of carboplatin-loaded surface-modified poly(lactide-co-glycolide) on retinoblastoma cells.

Methods: Carboplatin-loaded poly(lactide-co-glycolide) with or without sodium alginate surface modification was prepared using sodium alginate-poly(lactide-co-glycolide) and poly(lactide-co-glycolide). The zeta potential and carboplatin release behavior were investigated.

Changes in laryngopharyngeal reflux after uvulopalatopharyngoplasty for obstructive sleep apnea: An observational study.

Purpose: To estimate laryngopharyngeal reflux (LPR) changes after uvulopalatopharyngoplasty (UPPP) for obstructive sleep apnea (OSA) using the reflux symptom index (RSI) and reflux finding score (RFS) questionnaires.

Methods: A total of 91 participants were recruited and divided into three groups: control (n = 27), OSA mild to moderate (n = 29), and OSA severe (n = 35) groups according to polysomnography. All participants completed the preoperative RSI, and underwent blinded evaluation on videolaryngoscopy using the RFS questionnaire.

Diagnosis of lymph node metastasis in head and neck squamous cell carcinoma using deep learning.

Background: To build an automatic pathological diagnosis model to assess the lymph node metastasis status of head and neck squamous cell carcinoma (HNSCC) based on deep learning algorithms.

Study Design: A retrospective study.

Methods: A diagnostic model integrating two-step deep learning networks was trained to analyze the metastasis status in 85 images of HNSCC lymph nodes.

Environmental and sensitization variations among asthma and/or rhinitis patients between 2008 and 2018 in China.

Background: Little is known about the changes in allergen sensitization in China secondary to the environmental variations over the past decade. We aimed at investigating the variations in sensitization among asthma and/or rhinitis patients in China between 2008 and 2018.

Methods: This study analyzed cross-sectional data from national surveys conducted in China in 2008 and 2018.

Does Chinese foreign direct investment harm CO2 emissions in the Belt and Road Economies.

China's Going Global Strategy and Belt and Road Initiative gained great attention among scholars. Moreover, it is believed that Chinese investments abroad cause serious social and environmental externalities. Hence, in this paper, we examine how China's foreign direct investments influence the carbon emissions of 35 Belt and Road Initiative countries from 2000 to 2019.

Unexpected role of electronic coupling between host redox centers in transport kinetics of lithium ions in olivine phosphate materials.

The discrepancy between the trend in the diffusion coefficient of a lithium ion ( ) and that in the activation energy of ion hopping signals hidden factors determining ion transport kinetics in layered olivine phosphate materials (LiMPO). Combining density functional theory (DFT) calculations and the Landau-Zener electron transfer theory, we unravel this hidden factor to be the electronic coupling between redox centers of the host materials. The ion transport process in LiMPO is newly described as an ion-coupled electron transfer (ET) reaction, where the electronic coupling effect on is considered by incorporating the electronic transmission coefficient into the rate constant of the transfer reaction.

miR-125a-5p-targeted regulation of TRA2β expression inhibits proliferation and metastasis of hepatocellular carcinoma cells.

Objective: To explore the regulation of miR-125a-5p in hepatocellular carcinoma (HCC) and its mechanisms.

Methods: By transfecting a miR-125a-5p sequence and an interfering sequence of miR-125a-5p-s into human HCC cell lines HCC-LM3 and HepG2, miR-125a-5p-related levels were assesed by Western blot. The abilities of cell proliferation and migration were assessed by cell culture and Transwell assay, respectively.

One-pot construction of nitrogen-rich polymeric ionic porous networks for effective CO capture and fixation.

Facile preparation of ionic porous networks (IPNs) with large and permanent porosity is highly desirable for CO capture and transformation but remains a challenge. Here we report a one-pot base-mediated construction of nitrogen-rich IPNs through a combination of nucleophilic substitution and quaternisation chemistry from H-imidazole. This strategy, as proven by the model reactions of 1-imidazole or 1-methyl-1-imidazole with cyanuric chloride, allows for fine regulation of porosity and physicochemical properties, leading to nitrogen-rich IPNs featuring abundant ionic units and radicals.

Design of well-defined shell-core covalent organic frameworks/metal sulfide as an efficient Z-scheme heterojunction for photocatalytic water splitting.

Development of a covalent-organic framework (COF)-based Z-scheme heterostructure is a promising strategy for solar energy driven water splitting, but the construction of a COF-based Z-scheme heterostructure with well-defined architecture, large contact area and intimate contact interfaces is scarce. Herein, we fabricated a direct Z-scheme heterostructure COF-metal sulfide hybrid (T-COF@CdS) with shell-core architecture by self-polymerization of 1,3,5-benzenetricarboxaldehyde and 2,4,6-tris(4-aminophenyl)-1,3,5-triazine on CdS. The formed C-S chemical bonding between T-COF and CdS could provide a very tight and stable interface.