Planar Pentacoordinate Bromine in Global Minimum Br6Li5.

Delocalized multicenter bonds play a crucial role in clusters with a planar hypercoordinate center(s), making it difficult for highly electronegative elements, especially halogen atoms, to achieve the planar hypercoordinate arrangement. Herein, we introduce a star-like cluster Br6Li5-, whose global minimum contains a planar pentacoordinate bromine (ppBr). In this cluster, the central ppBr atom coordinates with five alkali metal Li atoms, which in turn bridge an equal number of electronegative Br atoms in the periphery, leading to the formation of the binary cluster Br6Li5-.

Synthesis of Headful Packaging Phages Through Yeast Transformation-Associated Recombination.

De novo synthesis of phage genomes enables flexible genome modification and simplification. This study explores the synthetic genome assembly of phage vB_PaeS_SCUT-S4 (S4), a 42,932 bp headful packaging phage, which encapsidates a terminally redundant, double-stranded DNA genome exceeding unit length. We demonstrate that using the yeast TAR approach, the S4 genome can be assembled and rebooted from a unit-length genome plus a minimal 60 bp terminal redundant sequence.

Flexible Vibration Sensors with Omnidirectional Sensing Enabled by Femtosecond Laser-Assisted Fabrication.

Vibration sensors are integral to a multitude of engineering applications, yet the development of low-cost, easily assembled devices remains a formidable challenge. This study presents a highly sensitive flexible vibration sensor, based on the piezoresistive effect, tailored for the detection of high-dynamic-range vibrations and accelerations. The sensor's design incorporates a polylactic acid (PLA) housing with cavities and spherical recesses, a polydimethylsiloxane (PDMS) membrane, and electrodes that are positioned above.

Investigating the Effect and Potential Mechanism of Rhamnetin 3--α-Rhamnoside on Acute Liver Injury In Vivo and In Vitro.

: Rhamnetin 3--α-rhamnoside (ARR) is a major flavonoid of the herb Franch. & Sav., which has been used for treating liver diseases in China.

Influence of Initial Gap, Voltage, and Additives on Zinc Microcolumn Morphology by Local Electrochemical Deposition.

Local electrochemical deposition (LECD) is an innovative additive manufacturing technology capable of achieving precise deposition of metallic microstructures. This study delves into the ramifications of pivotal operational parameters-namely, the initial electrode gap, deposition voltage, and additive concentration-on the morphology of zinc microcolumns fabricated through LECD. A holistic approach integrating experimental methodologies with finite element simulations was adopted to scrutinize the influence of these variables on the microcolumns' dimensions, surface morphology, and structural integrity.

Neuroinflammation: A Driving Force in the Onset and Progression of Alzheimer's Disease.

: The goal of this commentary is to highlight several key components of the inflammatory process as it relates to amyloid toxicity in Alzheimer's disease (AD), including the role of neuroinflammatory factors and peripheral inflammatory events. : Google Scholar and PubMed were used to find articles with the following keywords: Alzheimer's disease, amyloids, neuroinflammation, peripheral inflammation, microglia, cytokines, and treatments. Sources that were case reports, not peer-reviewed, or older than 30 years were excluded.

Luminescent Lanthanide Infinite Coordination Polymers for Ratiometric Sensing Applications.

Ratiometric lanthanide coordination polymers (Ln-CPs) are advanced materials that combine the unique optical properties of lanthanide ions (e.g., Eu, Tb, Ce) with the structural flexibility and tunability of coordination polymers.

: Phytochemical Profile and the Cosmeceutical and Dermatological Properties of Its Active Fraction from the Whole Plant.

Natural products and botanicals continue to play a very important role in the development of cosmetics worldwide. The chemical constituents of a fine active fraction of the whole plant extract of Walp., and the tyrosinase and matrix metalloproteinase-1 (MMP-1) inhibitory and antioxidant activities of this fraction were investigated.

Relationship of Biochemical and Sonographic Markers with Disease Severity in Rosacea Patients Without Cardiovascular Disease.

Rosacea is a chronic inflammatory skin disorder characterized by central facial redness, papulopustular lesions, and occasionally phymatous changes. There is ongoing debate regarding rosacea as a cutaneous disease with systemic inflammatory effects and its associations with cardiovascular diseases. Although the pathogenesis of both atherosclerosis and rosacea demonstrate notable similarities, particularly in the central role of inflammation, significant gaps in understanding these connections remain.

Experimental Investigation on Macroscopic and Microscopic Mechanical Properties of Geopolymer-Stabilized Macadam.

Geopolymer, as a promising inorganic binding material, holds potential for use in constructing base layers for highway pavements. This study aims to evaluate the mechanical properties of geopolymer-stabilized macadam (GSM) at both the micro- and macro-scale by a series of tests, demonstrating that high-Ca GSM is a high-quality material for pavement base layers. The results demonstrated that GSM exhibits outstanding mechanical and fatigue properties, significantly surpassing those of cement-stabilized macadam (CSM).

Effect of Speciation Transformation of Cadmium (Cd) on P-Wave Velocity Under Moisture Regulation in Soils.

This study aims to investigate the influence of cadmium (Cd) speciation transformation on P-wave velocity under different soil moisture conditions, providing critical insights into the subsurface characteristics of contaminated soils. Taking Cd-contaminated soil as the research subject, P-wave velocity and the speciation distribution of Cd in soils with different moisture contents and Cd adsorption levels were measured. The results reveal that when the soil is contaminated by Cd, the porosity is altered and it eventually lead to change P-wave velocity.

Effect of Inherent Mg/Ti Interface Structure on Element Segregation and Bonding Behavior: An Ab Initio Study.

To provide insight into the interface structure in Ti particle-reinforced Mg matrix composites, this study investigates the inherent Mg/Ti interface structure formed during the solidification of supercooled Mg melt on a (0001)Ti substrate using ab initio molecular dynamics (AIMD) simulations and density function theory (DFT) calculation. The resulting interface exhibits an orientation relationship of 0001Mg//0001Ti with a lattice mismatch of approximately 8%. Detailed characterizations reveal the occurrences of 0001Mg plane rotation and vacancy formation to overcome the lattice mismatch at the inherent Mg/Ti interface while allowing Mg atoms to occupy the energetically favorable hollow sites above the Ti atomic layer.

Eliminating Anisotropy of 7085 Alloy Forgings via Temperature Combination Control During Two-Stage Multi-Directional Forging.

Due to its high mechanical properties and low quench sensitivity, 7085 aluminum alloy is suitable for the aircraft industry. However, large cross-section forgings of 7085 alloy usually have over 40% anisotropy in mechanical behaviors, especially in the vertical direction. In this study, two-stage multi-directional forgings (MDFs) with different temperature combinations, isothermal medium-temperature composite MDF (MC-MDF) and isothermal hot MDF (H-MDF), were applied to 7085 aluminum alloy ingots.

Effect of Polypropylene and Straw Fiber Materials on the Unconfined Compressive Strength of Tailings and Wasted Stone Mixed Backfill.

Ensuring the mechanical performance of backfill materials while reducing cementation costs is a key challenge in mine backfill research. To address this, fiber materials such as polypropylene (PP) fiber and rice straw (RS) fiber have been incorporated into cement-based mixtures for mine backfilling. This study investigates the effects of PP and RS fibers on the mechanical properties, flow characteristics, and microstructure of Tailings and Wasted Stone Mixed Backfill (TWSMB).

Effects of Pre-Deformation in Corrosion Fatigue Crack Growth of Al-Mg-Zn Alloy.

This study investigated the effect of pre-deformation on the corrosion fatigue crack propagation (CFCG) of Al-Mg-Zn alloy in a corrosive environment. Tensile tests at different pre-deformation levels and molecular dynamics simulations analyzed changes in dislocation density. Corrosion fatigue experiments were conducted in a 3.

Stability and Rheological Properties of Grouts with Waste Glass Powder as Cement Replacement: Influences of Content and Alkali Activator.

Effective recycling and utilization of waste glass is a critical issue that urgently needs to be addressed. This study aims to explore the feasibility of using ground waste glass powder (particle size ≤ 75 μm) as a supplementary cementitious material to partially replace cement in the preparation of low-carbon and environmentally friendly grouting materials. The research systematically evaluates the impact of waste glass powder (WGP) on the fresh properties (particularly the stability and rheological characteristics) of cement-based grouting materials under various conditions, including WGP content (0-40%), the addition of NaOH activator (NaO content of 4%) or not, and water-solid ratio (/ 0.

Influence of Processing Parameters on Flow Behaviour of Ultra-Large-Section Beam Blank Continuous Casting Mould.

The complex cross-sectional shape of oversized beam blanks and the size effect of ultra-large-section beam blanks create severe issues related to the surface and internal quality of the castings. To ensure quality and control in the production of ultra-large-section beam blanks, a numerical and physical model of molten steel flow in the three-port submerged entrance nozzle (SEN) mould, with section dimensions of 1300 × 510 × 140 mm, was established. This model was created using numerical simulations and NSGA-II genetic algorithm optimisation, and the impact of the casting speed and SEN immersion depth on the mould's flow behaviour was investigated.

Mechanical Model of Tensile Loading of Geotechnical Reinforcement Materials.

To reveal the mechanical behavior and deformation patterns of geotechnical reinforcement materials under tensile loading, a series of tensile tests were conducted on plastic geogrid rib, fiberglass geogrid rib, gabion steel wire, plastic geogrid mesh, fiberglass geogrid mesh, and gabion mesh. The full tensile force-strain relationships of the reinforcement materials were obtained. The failure modes of different geotechnical reinforcement materials were discussed.

First Report and Phylogenetic Analysis of Mitochondrial Genomes of and .

The mitochondrial genome, highly conserved across species, is crucial for species identification, phylogenetic analysis, and evolutionary research. and , two species with significant forensic value, have been understudied in terms of genetic data. In this study, the complete mitochondrial genomes of (15,623 bp) and (15,729 bp) were sequenced and analyzed.

Integrated Genetic Diversity and Multi-Omics Analysis of Colour Formation in Safflower.

Safflower ( L.) is a medicinal and edible cash crop that is widely cultivated worldwide. However, the genetic diversity of safflower germplasm resources and the reasons for the variations in safflower flower colour remain unclear.

Neohesperidin Mitigates High-Fat-Diet-Induced Colitis In Vivo by Modulating Gut Microbiota and Enhancing SCFAs Synthesis.

Previous research has consistently shown that high-fat diet (HFD) consumption can lead to the development of colonic inflammation. Neohesperidin (NHP), a naturally occurring flavanone glycoside in citrus fruits, has anti-inflammatory properties. However, the efficacy and mechanism of NHP in countering prolonged HFD-induced inflammation remains unclear.

Research on Dry Coupling Technology in the Ultrasonic Non-Destructive Testing of Concrete.

In the health monitoring and safety assessments of concrete structures, ultrasonic non-destructive testing (NDT) technology has become an indispensable tool due to its non-destructive nature, efficiency, and precision. However, when used in inspecting irregular concrete surfaces, traditional planar ultrasonic transducers often encounter energy loss and signal attenuation induced by poor interface coupling, which significantly reduces the accuracy and reliability of the test results. To address this problem, this article proposes a point-contact dry coupling ultrasonic transducer solution, which enables efficient acquisition of ultrasonic signals within concrete without the need for couplants.

Enhancement of Doxorubicin Efficacy by Bacopaside II in Triple-Negative Breast Cancer Cells.

Background: Triple-negative breast cancer (TNBC) is an aggressive subtype with limited treatment options and high resistance to chemotherapy. Doxorubicin is commonly used, but its efficacy is limited by variable sensitivity and resistance. Bacopaside II, a saponin compound, has shown anti-cancer potential.

Reeve's Muntjac () Habitat Suitability Under Climate Change Scenarios in Hupingshan National Nature Reserve, China.

Climate change and human disturbance are critical factors affecting the habitat distribution of wild animals, with implications for management strategies such as protecting migration corridors, habitat restoration, and species conservation. In the Hupingshan National Nature Reserve (NNR), Reeve's muntjac () is a key prey species for the South China tiger (), which is extinct in the wild and targeted for reintroduction by the Chinese government. Thus, understanding the habitat distribution and abundance of Reeve's muntjac is essential to ensure the survival and sustainability of reintroduced tiger populations.