6,363 results match your criteria: "Central Sheep & Wool Research Institute[Affiliation]"

Epidemiology and Molecular Identification of in Sheep and Goats in Mpwapwa District, Tanzania: Factors to Consider in Control Plans.

Vet Med Int

December 2024

Department of Veterinary Microbiology, Parasitology and Biotechnology, College of Veterinary Medicine and Biomedical Sciences, Sokoine University of Agriculture, P.O. Box 3019, Morogoro, Tanzania.

Article Synopsis
  • - Cerebral coenurosis is a serious disease affecting sheep and goats globally, with a prevalence of 13.5% in Tanzania's Mpwapwa District, showing higher rates in goats (15.9%) compared to sheep (4.8%).
  • - A study identified key risk factors linked to the origins of the animals, particularly in certain areas like Chipogoro and Iwondo.
  • - Knowledge among sheep and goat keepers about the disease is low, especially regarding infection cycles and zoonotic potential, emphasizing the need for improved education and control measures in livestock management.
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A systematic review and meta-analysis on the prevalence of amphistome infection in domestic ruminants in the sub-Saharan Africa region.

J Helminthol

December 2024

School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Westville Campus, Durban4001, South Africa.

Systematic review and meta-analysis were conducted to provide comprehensive information on the prevalence of amphistome infections in domestic ruminants in sub-Saharan Africa. A systematic search of peer-reviewed articles published between 2002 and 2023 was conducted. Prevalence estimates and meta-analysis were based on 76 peer-reviewed articles which met the inclusion criteria.

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Climate change is one of the largest threats to grassland plant species, which can be modified by land management. Although climate change and land management are expected to separately and interactively influence plant demography, this has been rarely considered in climate change experiments. We used a large-scale experiment in central Germany to quantify the effects of grassland management, climate change, and their joint effect on the demography and population growth rate of 11 plant species all native to this temperate grassland ecosystem.

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Development of an automatic tubular chemiluminescence immunoassay using magnetic particles for the detection of antibodies against foot-and-mouth disease virus serotype A.

Microb Pathog

February 2025

Lanzhou Shouyan Biotechnology Co., Ltd, Lanzhou, 730046, China; State Key Laboratory for Animal Disease Control and Prevention, National Foot-and-Mouth Diseases Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, China. Electronic address:

Article Synopsis
  • Foot-and-mouth disease virus (FMDV) leads to major financial losses in animal farming, making antibody monitoring post-vaccination crucial for assessing vaccine effectiveness.
  • A new automated tubular chemiluminescence immunoassay method (A-MPCLIA) was developed to detect antibodies against FMDV serotype A, showing high diagnostic sensitivity (96.05%) and specificity (99%).
  • A-MPCLIA is quick (under 20 minutes for detection) and demonstrated strong correlations with existing tests, suggesting it could be a reliable method for future antibody detection against FMDV serotype A.
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Article Synopsis
  • Persistent subcutaneous granulomas develop at the injection site after administering aluminium oxyhydroxide (AlOOH), a common vaccine adjuvant, and can facilitate the infection of macrophages by small ruminant lentiviruses (SRLVs) in sheep.
  • The study involved 24 male lambs that underwent vaccination followed by SRLV infection, revealing that the granulomas, initially large, decreased in size over time and exhibited various features including central necrosis and keratin presence.
  • The research highlighted significant differences in the expression of the mannose receptor and the restriction factor A3Z1 in relation to the vaccine type and time, suggesting that macrophage polarization might affect SRLV infection, though the overall structure of the granulomas remained
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Introduction: In severe cases, an infection with the Borna Disease Virus 1 (BoDV-1), the causative agent of Borna disease in horses, sheep, and other domestic mammals, was reported to be accompanied by cognitive dysfunctions, seizures, deep coma, or severe to fatal encephalitis in humans. In addition, asymptomatic or mild courses of BoDV-1 infection are discussed to act as a co-factor in the etiology of Major Depressive Disorder (MDD). Previously, studies using electroencephalography (EEG) reported BoDV-1-dependent changes in event-related potentials (ERPs), thus indicating the use and added value of non-invasive studies in Borna research.

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Immunohistochemical assessment of ERM proteins (ezrin, radixin, moesin) in the ovaries of different species.

Tissue Cell

November 2024

Department of Biomedical Sciences and Pathobiology, Center of Pathobiology, University of Veterinary Medicine, Vienna, Austria; VetCore Facility for Research, University of Veterinary Medicine, Vienna, Austria. Electronic address:

Article Synopsis
  • Ezrin, radixin, and moesin (ERM) proteins connect membrane proteins to the actin cytoskeleton, but their role in healthy reproductive tissues is under-researched.
  • A study used immunohistochemistry to analyze the distribution of these proteins in ovaries from various animal species, including mice, dogs, and pigs.
  • Findings revealed differences in localization and expression of ERM proteins across species and ovarian structures, which could enhance our understanding of their physiological roles in female reproduction.
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Detection of infection in raw milk of livestock in Famenin, West part of Iran.

Iran J Vet Res

January 2024

Department of Microbiology, Faculty of Veterinary Sciences, Ilam University, Ilam, Iran.

Article Synopsis
  • * A total of 738 raw milk samples were collected, with MRT revealing a 6.23% positivity rate, primarily from sheep (91.30%), though no positive results came from cattle.
  • * PCR confirmed that 78.26% of MRT-positive samples were from the brucella genus, emphasizing the need for routine raw milk assessments to identify and manage brucellosis infection effectively.
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Background: Peste des petits ruminants (PPR) is a viral disease that affects domestic and wild small ruminants and camels in Africa, the Middle East, and Asia. Following the successful eradication of rinderpest, the World Organization for Animal Health (WOAH) and the Food and Agriculture Organization (FAO) have undertaken to eradicate PPR by 2030. Regular surveillance and monitoring of the disease in various regions of Ethiopia are crucial to achieving this goal.

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Genomic Insights into Tibetan Sheep Adaptation to Different Altitude Environments.

Int J Mol Sci

November 2024

Key Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.

Article Synopsis
  • Recent research has focused on how animals, like Tibetan sheep, adapt to low oxygen (hypoxic) conditions at various altitudes, particularly examining genetic factors.
  • A study sequenced the genomes of 60 Tibetan sheep from three altitude groups (medium, high, and ultra-high) and found distinct genetic differences, with some groups exchanging genes due to geographical proximity.
  • Findings indicate that ultra-high-altitude adaptation genes enhance oxygen uptake mechanisms, while high-altitude genes influence mitochondrial function and cellular processes, revealing critical insights into how these sheep survive in oxygen-scarce environments.
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Genome-Wide Selection Signals Reveal Candidate Genes Associated with Plateau Adaptation in Tibetan Sheep.

Animals (Basel)

November 2024

Key Laboratory of Animal Genetics and Breeding on the Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.

Article Synopsis
  • Tibetan sheep have specific adaptations that help them survive in the harsh conditions of the Qinghai-Tibet Plateau, but the underlying genetic mechanisms for these adaptations are not well understood.
  • The study involved analyzing whole-genome resequencing data from Tibetan sheep at different altitudes, leading to the identification of a significant number of candidate genes related to high-altitude adaptation.
  • Key genes were found to be associated with several important signaling pathways, offering insights into their roles in helping Tibetan sheep manage low oxygen levels at high altitudes.
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Prevalence, risk factors and molecular identification of paramphistomid species in sheep from a Spanish endemic area.

Ir Vet J

November 2024

Faculty of Veterinary Sciences, Universidade de Santiago de Compostela, Investigación en Sanidad Animal: Galicia (Grupo INVESAGA), Lugo, Spain.

Article Synopsis
  • Paramphistomids, trematodes affecting the rumen, are increasingly found in sheep in northwestern Spain, with 14% of the sheep and 44% of the farms testing positive for infection.
  • The study analyzed 826 fecal samples and identified risk factors such as age, farm management practices, and environmental conditions that influence infection rates and egg shedding of these parasites.
  • Molecular identification confirmed the presence of Calicophoron daubneyi, marking the first time this species has been identified in Spanish sheep, highlighting the growing concern of paramphistomid infections in this region.
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Communal grazing is the predominant farming system in Ethiopia and the livelihood of millions of people depend on it. Gastrointestinal nematodes represent a serious threat to the sustainability of these systems, and there is further concern due to the worldwide spread of anthelmintic resistance (AR). This study aimed to assess nematode control practices and anthelmintic efficacy in three districts of central Ethiopia, where sheep, goats and cattle are reared together by resource-poor farmers.

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Domesticated sheep have adapted to contrasting and extreme environments and continue to play important roles in local community-based economies throughout Africa. Here we review the Neolithic migrations of thin-tailed sheep and the later introductions of fat-tailed sheep into eastern Africa. According to contemporary pictorial evidence, the latter occurred in Egypt not before the Ptolemaic period (305-25 BCE).

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In Sweden, it is recommended to treat rams at sheep markets with ivermectin and then keep them in quarantine to minimise the risk of transmission of Haemonchus contortus between farms. The aim of this study was to evaluate the effectiveness of this practise. Accordingly the gastrointestinal parasite status of 50 rams purchased at two sheep markets in central Sweden in autumn 2019 was investigated using faecal samples collected on the day of sale (test 1), 12 ± 3 days after ivermectin injection (test 2, in quarantine) and a few months later before inclusion in the new flocks (test 3).

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Advanced 2D Nanomaterials for Phototheranostics of Breast Cancer: A Paradigm Shift.

Adv Biol (Weinh)

January 2025

Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein, P.O. Box 17011, Johannesburg, 2028, South Africa.

Breast cancer is the leading cause of women's deaths and associated comorbidities. The advanced and targeted strategies against breast cancer have gained considerable attention due to their potential enhanced therapeutic efficacy over conventional therapies. In this context, phototherapies like photodynamic therapy (PDT) and photothermal therapy (PTT) have shown promise as an effective and alternative strategy due to reduced side effects, noninvasiveness, and spatiotemporal specificity.

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Coxiella burnetii caused lumbar infection: A case report and literature review.

Diagn Microbiol Infect Dis

January 2025

Department of Clinical Laboratory, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266000, China. Electronic address:

Coxiella burnetii (C. burnetii)is a significant microbe linked to the zoonotic disease Q fever, known for its atypical clinical manifestations and sporadic cases. It can cause lumbar infections.

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Continuously monitoring human airway conditions is crucial for timely interventions, especially when airway stents are implanted to alleviate central airway obstruction in lung cancer and other diseases. Mucus conditions, in particular, are important biomarkers for indicating inflammation and stent patency but remain challenging to monitor. Current methods, reliant on computational tomography imaging and bronchoscope inspection, pose risks due to radiation and lack the ability to provide continuous real-time feedback outside of hospitals.

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Article Synopsis
  • Mammary epithelial cells in sheep develop differently during pregnancy and lactation, with East FriEsian sheep known for high milk production compared to Sewa sheep, which has lower milk output.
  • Researchers established mammary epithelial cell lines from both breeds and confirmed their identities through specific markers.
  • RNA-seq analysis revealed significant differences in gene expression between the two breeds, highlighting 1813 differentially expressed genes and identifying ATF3 and MPP7 as key candidates for lactation regulation.
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Background: The Changthangi sheep thrive at high altitudes in the cold desert regions of Ladakh, India while Muzaffarnagri sheep are well-suited to the low altitude plains of northern India. This study investigates the molecular mechanisms of pulmonary adaptation to diverse environments by analyzing gene expression profiles of lung tissues through RNA sequencing.

Methods And Results: Four biological replicates of lung tissue from each breed were utilized to generate the transcriptomic data.

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Sheeppox virus genome sequences from the European outbreaks in Spain, Bulgaria, and Greece in 2022-2024.

Arch Virol

October 2024

Sciensano (Belgium), Service of 'Exotic and Vector borne diseases' (ExoVec), Groeselenberg 99, 1180, Ukkel, Belgium.

In 2022-2024, three outbreaks of sheeppox (SPP) were reported in the European Union. These occurred in Spain, Bulgaria, and Greece and had serious economic consequences due to animal losses and trade restrictions. Five sheeppox virus (SPPV) whole-genome sequences (WGSs) were determined from samples collected during these outbreaks and analyzed in the context of all other published WGSs.

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Cadmium is one of the most important environmental contaminants. Animals grazing on natural pastures are particularly exposed to cadmium. Sheep are mostly reared in extensive and grazing systems.

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Exceptional Bluetongue virus (BTV) and Epizootic hemorrhagic disease virus (EHDV) circulation in France in 2023.

Virus Res

December 2024

ANSES/INRAE/ENVA-UPEC, UMR 1161 Virology, Laboratoire de santé animale, 14 rue Pierre et Marie Curie, 94700 Maisons-Alfort, France.

Article Synopsis
  • - Bluetongue (BT) and Epizootic Hemorrhagic Disease (EHD) are important animal diseases impacting cattle and sheep, caused by viruses transmitted by biting midges, with recent outbreaks noted in France during the summer of 2023.
  • - Genomic analysis revealed three viruses involved in the outbreaks: EHDV-8, which matches strains found in southern Europe since 2021, and two different strains of BTV, including a novel BTV-8 strain and an established BTV-4 strain.
  • - The 2023 outbreaks indicate unusual dynamics in the circulation and emergence of these viruses in France, prompting further investigation into the epidemiological factors contributing to their spread.
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Various prenatal factors including the number of littermates (fraternity size) and exposure to male littermate (fraternity sex ratio) during fetal period have been reported to influence postnatal fertility in the mammals. The present research was conducted to study the association of fraternity size and sex ratio with reproductive performance of nulliparous ewes and does. To this end, data associated with number of littermates, exposure to male littermate, birth weight, age at first pregnancy, as well as litter size, sex ratio of offspring, litter weight, and birth weight of female and male offspring after the first parturition retrieved from the database of sheep (n = 536 Romane and 289 Blanche du Massif Central ewes) and goat (n = 174 Alpine and 267 Saanen does) flocks.

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Article Synopsis
  • * A study collected data from 57 brucellosis cases and 114 matched controls to explore risk factors, finding that factors like consumption of homemade dairy products and involvement in animal slaughter significantly increased infection risk.
  • * The study concluded that close contact with unvaccinated livestock contributed to the rise in brucellosis cases, highlighting the need for better animal health practices and public awareness.
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