Overlooked poor-quality patient samples in sequencing data impair reproducibility of published clinically relevant datasets.

Background: Reproducibility is a major concern in biomedical studies, and existing publication guidelines do not solve the problem. Batch effects and quality imbalances between groups of biological samples are major factors hampering reproducibility. Yet, the latter is rarely considered in the scientific literature.

A Systematic Review of Lipid-Focused Cardiovascular Disease Research: Trends and Opportunities.

Lipids are important modifiers of protein function, particularly as parts of lipoproteins, which transport lipophilic substances and mediate cellular uptake of circulating lipids. As such, lipids are of particular interest as blood biological markers for cardiovascular disease (CVD) as well as for conditions linked to CVD such as atherosclerosis, diabetes mellitus, obesity and dietary states. Notably, lipid research is particularly well developed in the context of CVD because of the relevance and multiple causes and risk factors of CVD.

Biology and Rearing of an Emerging Sugar Beet Pest: The Planthopper .

The rapid spread of the bacterial yellowing disease Syndrome des Basses Richesses (SBR) has a major impact on sugar beet () cultivation in Germany, resulting in significant yield losses. SBR-causing bacteria are transmitted by insects, mainly the Cixiid planthopper . However, little is known about the biology of this emerging vector, including its life cycle, oviposition, developmental stages, diapauses, and feeding behavior.

Climate change will influence disease resistance breeding in wheat in Northwestern Europe.

Wheat productivity is threatened by global climate change. In several parts of NW Europe it will get warmer and dryer during the main crop growing period. The resulting likely lower realized on-farm crop yields must be kept by breeding for resistance against already existing and emerging diseases among other measures.

Modelling of post-diapause development and spring emergence of (Lepidoptera: Tortricidae).

The prediction of the post-diapause emergence is the first step towards a comprehensive decision support system that can contribute to a considerable reduction of pesticide use by forecasting a precise spraying date. The cumulative field emergence can be described as a function of the cumulative development rate. We investigated the impact of seven constant temperatures and five light regimes on post-diapause development in laboratory experiments.