1 results match your criteria: "Central Hospital of Shanghai Jiao Tong University School of Medicine[Affiliation]"
Hydrochloride fasudil attenuates brain injury in ICH rats.
Transl Neurosci
April 2020
Department of Neurology, The Affiliated Shanghai Songjiang Central Hospital of Shanghai Jiao Tong University, Central Hospital of Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Article Synopsis
- The study aimed to explore how hydrochloride fasudil (HF) protects the brain in rats after suffering an intracerebral hemorrhage (ICH).
- Rats were divided into four groups for the experiment: normal, sham-operated, ICH, and ICH with HF treatment, assessing various biomarkers and inflammation responses.
- Results indicated that HF treatment significantly reduced the levels of a protein called ROCK2, decreased inflammatory responses, minimized brain swelling, and protected against neuronal death compared to untreated rats.