1 results match your criteria: "Central Hospital of Enshi Tujia and Miao Autonomous Prefectures[Affiliation]"
[miR-520a-3p regulates the signaling pathway of cytokine secretion in cervical cancer].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
July 2020
Department of Oncology, Central Hospital of Enshi Tujia and Miao Autonomous Prefectures, Hubei Province, Enshi 445000, China.
Objective: To investigate the molecular mechanism of miR-520a-3p regulating the secretion of cytokines in cervical cancer.
Methods: The matching between miR-520a-3p and the NF-κB complex subunit RELA was analyzed by TargetScanHuman, and then the luciferase reporting system was used to detect whether miR-520a-3p targeted the NF-κB complex subunit RELA. After cervical cancer HELA cells stimulated by LPS, in the overexpression group or the knockout group, miR-520a-3p mimics or inhibitor were mixed with transfection reagent and dripped into HELA cells.