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CD9 modulates proliferation of human glioblastoma cells via epidermal growth factor receptor signaling.
Mol Med Rep
July 2015
Department of Medical Teaching, Xianyang Hospital of Yanan University, Central Hospital of 20th Bureau of China Railway Group, Xianyang, Shaanxi 712000, P.R. China.
The tetraspanin CD9 has previously been shown to be involved in various cellular activities, including proliferation and migration. In addition, CD9 has been shown to be associated with epidermal growth factor receptor (EGFR). A common characteristic of glioblastoma multiforme histology is EGFR amplification, which affects signal transduction processes.
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