Motion analysis for objective evaluation of psychomotor skills in Endoscopic Sinus Surgery.

Background: This study aims to digitalize surgical maneuvers in ESS using a motion capture system under standardized conditions provided by 3D printed-sinus models.

Methodology: Forty-seven otolaryngologists performed ESS on 3D printed models manufactured from computed tomography (CT) images of actual patients. Participants were classified to 3 groups according to the objective structured technical skills assessment score.

Mental workload during endoscopic sinus surgery is associated with surgeons' skill levels.

Introduction: Surgeons' mental workload during endoscopic sinus surgery (ESS) has not been fully evaluated. The assessment was challenging due to the great diversity of each patient's anatomy and the consequence variety of surgical difficulties. In this study, we examined the mental workload of surgeons with various surgical skill levels during ESS under the standardized condition provided by novel-designed 3D sinus models.

Case Report: Late spontaneous orbital subperiosteal hematoma after endoscopic sinonasal tumor resection.

Introduction And Importance: We report a case of spontaneous subperiosteal orbital hematoma many years after endoscopic sinonasal resection of malignancy.

Case Presentation: A 50-year-old female with a six-year history of endoscopic sinonasal resection of a poorly differentiated neuroendocrine tumor presented with two days of worsening frontal headache and left periocular swelling. A subperiosteal abscess was initially suspected on CT; however, MRI sequences revealed changes consistent with the diagnosis of hematoma.

Repetitive simulation training with novel 3D-printed sinus models for functional endoscopic sinus surgeries.

Background: The purpose of this study was to find a utility of a newly developed 3D-printed sinus model and to evaluate the educational benefit of simulation training with the models for functional endoscopic sinus surgery (FESS).

Material And Methods: Forty-seven otolaryngologists were categorized as experts (board-certified physicians with ≥200 experiences of FESS,  = 9), intermediates (board-certified physicians with <200 experiences of FESS,  = 19), and novices (registrars,  = 19). They performed FESS simulation training on 3D-printed models manufactured from DICOM images of computed tomography (CT) scan of real patients.

TLR Signals in Epithelial Cells in the Nasal Cavity and Paranasal Sinuses.

The respiratory tract is constantly at risk of invasion by microorganisms such as bacteria, viruses, and fungi. In particular, the mucosal epithelium of the nasal cavity and paranasal sinuses is at the very forefront of the battles between the host and the invading pathogens. Recent studies have revealed that the epithelium not only constitutes a physical barrier but also takes an essential role in the activation of the immune system.

Remote Training of Functional Endoscopic Sinus Surgery With Advanced Manufactured 3D Sinus Models and a Telemedicine System.

Traditionally, cadaveric courses have been an important tool in surgical education for Functional Endoscopic Sinus Surgery (FESS). The recent COVID-19 pandemic, however, has had a significant global impact on such courses due to its travel restrictions, social distancing regulations, and infection risk. Here, we report the world-first remote (Functional Endoscopic Sinus Surgery) FESS training course between Japan and Australia, utilizing novel 3D-printed sinus models.

Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells.

Background: From the first detection in 2019, SARS-CoV-2 infections have spread rapidly worldwide and have been proven to cause an urgent and important health problem. SARS-CoV-2 cell entry depends on two proteins present on the surface of host cells, angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2). The nasal cavity is thought to be one of the initial sites of infection and a possible reservoir for dissemination within and between individuals.