2,412 results match your criteria: "Centers for Disease Control and Prevention CDC.[Affiliation]"

Background: High-grade resistance to sulfadoxine-pyrimethamine in East and Southern Africa has prompted numerous trials evaluating intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin-piperaquine as an alternative to sulfadoxine-pyrimethamine.

Methods: We conducted individual participant data meta-analyses of randomised trials comparing IPTp with dihydroartemisinin-piperaquine to sulfadoxine-pyrimethamine on maternal, birth, and infant outcomes. We searched the WHO International Clinical Trials Registry Platform, ClinicalTrials.

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Background: Healthcare-associated bloodstream infections (BSI) threaten patient safety and are the third most common healthcare-associated infection (HAI) in low- and middle-income countries. An intensive-care-unit (ICU) based HAI surveillance network recording BSIs was started in India in 2017. We evaluated this surveillance network's ability to detect BSI to identify best practices, challenges, and opportunities in its implementation.

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Article Synopsis
  • Endurance exercise training (ExT) leads to significant changes in lipid composition across various tissues, highlighting the need for a deeper understanding of these alterations.
  • In a study involving Fischer-344 rats, it was found that both male and female rats show distinct lipid remodeling in tissues like the heart, liver, and skeletal muscle after different durations of ExT.
  • Exercise resulted in lower body fat and better cardiorespiratory fitness, with important changes in types of lipids (like phospholipids and ceramides) that could help explain how exercise benefits overall health.
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In the Global Poliovirus Laboratory Network (GPLN), participation and successful completion in annual proficiency test (PT) panels has been a part of the WHO accreditation process for decades. The PT panel is a molecular external quality assessment (mEQA) that evaluates laboratory preparedness, technical proficiency, the accuracy of data interpretation, and result reporting. Using the Intratypic Differentiation (ITD) real-time RT-PCR kits from CDC, laboratories run screening assays and report results in accordance with the ITD algorithm to identify and type polioviruses.

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Purpose: To investigate differences in teen-reported and parent-reported lifetime prevalence estimates of traumatic brain injury (TBI) symptoms, TBI evaluation, and TBI diagnosis among a nationally representative sample of teenagers aged 12-17 years old and their parents.

Methods: Parent-reported data from the 2021 to 2022 National Health Interview Survey linked with teen-reported data from the National Health Interview Survey-Teen July 2021-December 2022 (n = 1,153) were analyzed. Lifetime prevalence estimates for TBI symptoms (e.

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Article Synopsis
  • Sub-Saharan Africa has the highest chronic hepatitis B virus (HBV) infection rates globally, making national HBV prevalence estimates crucial for Kenya's viral hepatitis program.
  • In a study analyzing data from over 3,000 participants aged 15-64 in the 2018 Kenya Population-based HIV Impact Assessment, the national HBV prevalence was found to be 3.0%, equating to approximately 810,600 infected individuals in this age group.
  • The study revealed significant geographical variations in HBV prevalence, with higher rates in certain regions, among people living with HIV, older individuals, those with no formal education, and in lower economic groups; lack of formal education was notably linked to increased HBV infection risk.
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Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh.

Virol J

November 2024

Department of Pathobiology and Population Sciences, Royal Veterinary College (RVC), Hatfield, Hertfordshire, UK.

Background: Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 spread in some of the world's least developed countries (LDCs).

Methods: To begin to address this disparity, we studied the transmission dynamics of the virus in Bangladesh during the country's first COVID-19 wave by analysing case reports and whole-genome sequences from all eight divisions of the country.

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Who Gets a Code for Obesity? Reliability, Use, and Implications of Combining International Classification of Diseases-Based Obesity Codes, 2014-2021.

Child Obes

November 2024

Division of Nutrition, Physical Activity and Obesity, National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.

Many studies rely on the International Classification of Diseases, 9th or 10th Revision, Clinical Modification codes to define obesity in electronic health records data. While prior studies found misclassification and low sensitivity of codes for pediatric obesity, it remains unclear whether this misclassification is random and what are the implications of combining different code types to define obesity. We assessed prevalence, sensitivity, and specificity of obesity codes among 7.

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The World Trade Center (WTC) Health Program is a limited federal health care program that provides medical monitoring and treatment for WTC-related health conditions to responders and survivors impacted by the terrorist attacks on September 11, 2001.This study described the characteristics of the Program survivor members (who lived, worked, went to school, daycare or adult daycare or present in the New York City Disaster Area of 9/11/2001) to stimulate innovative ideas for improving healthcare services, generate new research interest, and serve as a reference for future research on this population. Administrative and medical claims data collected from the Program start date (07/01/2011) through 2022 were used.

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Background: Uncontrolled blood pressure is a significant public health problem associated with a high rate of mortality and morbidity worldwide. In Ethiopia, 48% of hypertensive patients have Uncontrolled blood pressure. Therefore, this study aimed to identify the determinants of uncontrolled blood pressure among adult hypertensive patients on follow-up at the Negele and Adola General Hospitals in the Guji Zone, Oromia, Ethiopia.

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Building Healthy, Equitable, and Resilient Communities: Lessons Learned From Multisector Community Partnerships Addressing the Social Determinants of Health.

J Public Health Manag Pract

January 2025

Author Affiliations: Program and Policy Evaluation to Advance Community Health, RTI International, Research Triangle Park, North Carolina (Dr DePriest and Dr Glasgow); Chronic Disease Prevention & Health Improvement, Association of State and Territorial Health Officials (ASTHO), Arlington, Virginia (Ms Bayer); Chronic Disease, National Association of County and City Health Officials (NACCHO), Washington, District of Columbia (Ms Weiss); and National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia (Dr Hacker).

Context: Multisector community partnerships play a pivotal role in public health strategy for understanding and addressing social determinants of health (SDOH) and promoting health equity. The work of these partnerships is well aligned with building community resilience.

Program: The Year 2 Improving Social Determinants of Health-Getting Further Faster (GFF) retrospective evaluation was designed to gather practice-based evidence that can inform future community-driven partnerships to improve chronic disease outcomes and advance health equity by addressing social determinants of health (SDOH).

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Purpose: Intimate partner violence (IPV) exposure in childhood is common, with impacts on lifespan well-being. However, there are knowledge gaps about needs and barriers to services for IPV survivors with children.

Method: We analyzed data from adults aged ≥ 19 years who resided in the U.

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Lifetime History of Head or Traumatic Brain Injury Before Age 9 and School Outcomes: Results From the Adolescent Brain Cognitive Development Study.

J Sch Health

December 2024

Huntsman Mental Health Institute, University of Utah School of Medicine, Salt Lake City, UT; Diagnostic Neuroimaging Laboratory, University of Utah, Salt Lake City, UT; Veterans Affairs VISN 19 Rocky Mountain Mental Illness Research, Education and Clinical Center (MIRECC), Salt Lake City, UT.

Background: Limited information about school outcomes among children (especially early childhood) with lifetime history of head injury, including traumatic brain injury (TBI), may inhibit efforts to support their academics and physical and mental health.

Methods: Baseline data (2016-2018) from the Adolescent Brain Cognitive Development (ABCD) study were analyzed to describe associations between parent-proxy reported lifetime history of head injury or TBI before age 9 and school outcomes and behavioral challenges among 9- and 10-year-old children.

Results: Having a lifetime history of head injury before age 9 was associated with increased odds of parent-perceived poor school performance (adjusted odds ratio [AOR] = 1.

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COVID-19 Deaths and Minority Health Social Vulnerability, in the U.S., January 1, 2020 through June 24, 2023.

J Racial Ethn Health Disparities

October 2024

Coronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases (NCIRD), Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA.

Article Synopsis
  • Health disparities leading to higher COVID-19 death rates are caused by social and structural factors, significantly affecting lower socioeconomic groups and socially vulnerable communities.
  • The study analyzed data from over a million COVID-19 deaths in the U.S., using the Minority Health Social Vulnerability Index (MHSVI) to categorize counties based on their social vulnerability.
  • Results showed that higher vulnerability correlated with increased death rates, except for those counties with better healthcare access, which saw lower death rates.
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Article Synopsis
  • Regulatory agencies and NITAGs evaluate the balance of vaccine benefits and harms, with DQCs (direct quantitative comparisons) being used to support decision-making during the COVID-19 pandemic.
  • The study reviewed 23 publications where DQCs were utilized, revealing their role in various situations, such as new safety signals and changing vaccine contexts.
  • While DQCs provided timely and transparent communication, their reliance on assumptions made them sensitive to changes and limited their applicability to different contexts, especially in the rapidly evolving COVID-19 situation.
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The effects of HIV self-testing on HIV incidence and awareness of status among men who have sex with men in the United States: Insights from a novel compartmental model.

Epidemics

December 2024

Centers for Disease Control and Prevention (CDC), National Center for HIV, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Division of HIV Prevention (DHP), Quantitative Sciences Branch (QSB), USA.

Background: The OraQuick In-Home HIV self-test represents a fast, inexpensive, and convenient method for users to assess their HIV status. If integrated thoughtfully into existing testing practices, accompanied by efficient pathways to formal diagnosis, self-testing could enhance both HIV awareness and reduce HIV incidence. However, currently available self-tests are less sensitive, particularly for recent infection, when compared to gold-standard laboratory tests.

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Occupational and industry prevalence of new long-term symptoms within American Red Cross blood donors with and without history of SARS-CoV-2 infection.

Am J Ind Med

December 2024

Coronavirus & Other Respiratory Viruses Division (CORVD) National Center for Immunization and Respiratory Diseases (NCIRD), Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.

Article Synopsis
  • - The study investigates the prevalence of long-term symptoms in blood donors based on their SARS-CoV-2 infection status, focusing on differences across various occupations and industries.
  • - Data was collected from nearly 28,000 donors, revealing that 45% of those previously infected reported new long-term symptoms, compared to 24% of those never infected, with higher symptom prevalence in certain job sectors like healthcare support and accommodation services.
  • - The findings suggest that certain occupational groups experience more long-term symptoms due to their exposure to COVID-19, indicating a potential need for workplace accommodations to support affected employees.
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Background: Phuket Province is a major tourist destination with a migrant workforce accounting for 10% of its population. Despite governmental efforts to adjust health insurance policies, migrants face healthcare access challenges. This study examines the current healthcare access situation and factors associated with unmet needs among migrants in Phuket Province.

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The epidemiology and circulation patterns of various rhinovirus types within populations remains under-explored. We generated 803 VP4/VP2 gene sequences from rhinovirus-positive samples collected from acute respiratory illness (ARI) patients, including both in-patient and outpatient cases, between 1st January and 31st December 2014 from eleven surveillance sites across Kenya and used phylogenetics to characterise virus introductions and spread. RVs were detected throughout the year, with the highest detection rates observed from January to March and June to July.

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During population-based HIV impact assessments (PHIAs), some participants who self-reported testing HIV-positive (PSRP) tested negative in one or more subsequent survey HIV tests. These unexpected discrepancies between their self-reported results and the survey results draw into question the validity of either the self-reported status or the test results. We analyzed PSRP with negative test results aged 15-59 years old using data collected from 2015 to 2021 in 13 countries, assessing prevalence, self-report status, survey HIV status, viral load, rapid tests and confirmatory tests, and answers to follow-up questions (such as years on treatment).

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Article Synopsis
  • HIV drug resistance (HIVDR) can decrease the effectiveness of antiretroviral drugs, and this study focused on assessing HIV-1 subtypes and drug resistance among key populations in Vietnam during 2018 and 2020.
  • The study recruited participants from hotspots for men who have sex with men (MSM) and female sex workers (FSW) in various provinces, and 42.5% of HIV-positive samples had a viral load indicating the need for further testing for drug resistance.
  • The results showed that CRF01_AE was the most common subtype, and 16.7% of participants had drug resistance mutations, with the majority being associated with NNRTI and NRTI classes, suggesting
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Purpose: Data on adverse childhood experiences (ACEs) among teens is collected using a single informant, a parent-proxy, or teen self-report. Little is known about alignment between these approaches.

Methods: Surveys were administered online to teens ages 15-17 and their parents (n = 522 dyads) using the AmeriSpeak panel.

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