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Prescription opioid use during pregnancy and risk for preterm birth or term low birthweight.

J Opioid Manag

July 2021

National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Preven-tion, Atlanta, Georgia. ORCID: https://orcid.org/0000-0001-6428-8523.

Objective: Examine the relationship between prescription opioid analgesic use during pregnancy and preterm birth or term low birthweight.

Design, Setting, And Participants: We analyzed data from the National Birth Defects Prevention Study, a US multisite, population-based study, for births from 1997 to 2011. We defined exposure as self-reported prescription opioid use between one month before conception and the end of pregnancy, and we dichotomized opioid use duration by ≤7 days and >7 days.

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