2 results match your criteria: "Center of reproduction and genetics Suzhou Municipal Hospital[Affiliation]"
Validation of a high-throughput and robust technique: BACs-on-beads assay (KaryoLite BoBs) for pre-implantation aneuploidy screening.
Taiwan J Obstet Gynecol
August 2017
Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, PR China. Electronic address:
Objective: This study aims to validate the BACs-on-Beads (BoB) technology as a robust and high throughput method for pre-implantation genetic screening (PGS) for aneuploidy.
Material And Methods: The performances with respect to the sensitivity, specificity, success rate and detection rate of this technique from new BoBs technology and traditional array chromosomal genomic hybridization (aCGH) were compared. And the use of BoBs as a screening tool for euploid embryos in PGS was evaluated.
Identification of small segmental translocations in patients with repeated implantation failure and recurrent miscarriage using next generation sequencing after in vitro fertilization/intracytoplasmic sperm injection.
Mol Cytogenet
December 2015
Center of reproduction and genetics Suzhou Municipal Hospital, Suzhou, Jiangsu P.R.China.
Background: To develop a novel preimplantation genetic screening (PGS) test using next generation sequencing(NGS) as a alternative to current array comparative genomic hybridization (array CGH) method for detection of small segmental translocations in two patients with repeated implantation failure (RIF) and recurrent miscarriage (RM). Inconsistent results were resolved by validation with fluorescence in situ hybridization (FISH).
Case Presentation: One couple with normal cytogenetic and array CGH result suffered from implantation failure.