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Center of Medical Sciences of Federal U... Publications | LitMetric

4 results match your criteria: "Center of Medical Sciences of Federal University of Pernambuco[Affiliation]"

Purpose: Inflammatory bowel disease (IBD) is a disease of increasing prevalence in developing countries. Obesity has emerged as a potential risk for IBD; however, the data in the literature are conflicting, and relevant studies in Brazil are limited. Here, we report body mass index profile (BMI) of patients with IBD treated at reference centers in three states of northeastern Brazil.

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Article Synopsis
  • Cutaneous involvement, particularly pyoderma gangrenosum (PG), is a common but complex extraintestinal manifestation of inflammatory bowel diseases like ulcerative colitis and Crohn's disease, presenting significant management challenges due to few clinical trials.
  • Four atypical PG case presentations highlight varied responses to treatments such as corticosteroids, cyclosporine, infliximab, and adalimumab in patients with underlying bowel conditions.
  • Effective treatment of PG often requires personalized approaches based on individual patient histories and specific lesion characteristics, emphasizing the need for tailored management strategies in gastroenterology.
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BACKGROUND Hypercoagulable states, including venous and arterial thromboses, manifesting as pulmonary thromboembolism or stroke have been observed in COVID-19; recently, gastrointestinal thrombotic events have also been reported. This case report describes a patient with COVID-19 and abdominal pain, who developed coagulopathy and a rare association of hepatic artery thrombosis. Common hepatic artery thrombosis is usually observed among liver transplantation patients and has not been described in infectious disease.

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Since the first reports of coronavirus disease 2019 (COVID-19) cases in December 2019 in China, numerous papers have been published describing a high frequency of liver injury associated with severe acute respiratory syndrome coronavirus 2 infection, many of them proposing a link between these findings and patient outcomes. Increases in serum aminotransferase levels (ranging from 16% to 62%) and bilirubin levels (ranging from 5% to 21%) have been reported and seem to be more often observed in patients with severe forms of COVID-19. Although absolute changes in these parameters are frequently seen, other variables, such as the ratio above the upper limit of normal, the onset of liver injury as a complication in severe cases and histopathological findings, reinforce that liver changes are of dubious clinical relevance in the course of this disease.

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