205 results match your criteria: "Center of Excellence in Biotechnology[Affiliation]"

This experiment was conducted to investigate the effects of different nitrogen fertilizers (potassium nitrate and/or urea) on shoot parameters, relative growth rate, net assimilation rate, and nitrogen fractions, as well as to conduct transmission electron microscopy, of L. (cowpea) and L. (sunflower) leaves.

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Background: This study aims to understand the influence of chlorophyll fluorescence parameters on yield of winter wheat in some areas of China. Nitrogen (N) application is believed to improve photosynthesis in flag leaf ultimately increase final yield.

Methods And Results: To understand the response of chlorophyll fluorescence parameters of wheat, flag leaf and the effect of N fertilization was carried out at booting stage under greenhouse during year 2018-2019 using winter wheat cultivar "Yunhan-20410' 'Yunhan-618".

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Rice () is an important staple food crop worldwide, especially in east and southeast Asia. About one-third of rice cultivated area is under saline soil, either natural saline soils or irrigation with brackish water. Salinity stress is among the devastating abiotic stresses that not only affect rice growth and crop productivity but also limit its cultivation area globally.

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Information regarding the germination and seedling growth behavior of a potential weed species is an important tool to manage weeds without the use of agricultural chemicals that cause harmful effects on human health and the environment. A series of experiments were directed to investigate the influence of different environmental factors (temperature, pH, NaCl, moisture stress, and seed burial depth) on germination and seedling emergence of perennial ryegrass (Lolium perenne L.) under controlled conditions.

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Surra is a non-cyclic parasitic disease caused by Trypanosoma evansi (T. evansi) and spread by biting flies. The disease has a severe impact on camel health, productivity, and market value, posing a significant threat to food safety and the economy.

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A comparison of logistic regression and classification tree to assess brucellosis associated risk factors in dairy cattle.

Prev Vet Med

June 2022

Department of Animal Medicine (Infectious Diseases), Faculty of Veterinary Medicine, Benha University, Moshtohor-Toukh, Kalyobiya 13736, Egypt. Electronic address:

Machine learning approaches have been increasingly utilized in the field of medicine. Brucellosis is one of the most common contagious zoonotic diseases with significant impacts on livestock health, reproduction, production, and public health worldwide. Therefore, our objective was to determine the seroprevalence and compare the logistic regression and Classification and Regression Tree (CART) data-mining analysis to assess risk factors associated with Brucella infection in the densest cattle populated Egyptian governorates.

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Molecular epidemiology and genetic characterization of Theileria orientalis in cattle.

Trop Anim Health Prod

May 2022

Department of Animal Medicine (Infectious Diseases), Faculty of Veterinary Medicine, Benha University, Moshtohor-Toukh, Kalyobiya, 13736, Egypt.

Theileria orientalis (T. orientalis) is a benign species of Theileria that is found all throughout the world, including Egypt. The purpose of this work was to determine the current status of T.

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Adverse effect of vaccination in xenogeneic animals.

Microb Pathog

May 2022

Electron Microscope Research Unit, Health Sciences Research Center, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.

Lumpy skin disease (LSD) is a devastating, emerging viral disease of cattle. It causes significant economic losses due to trade restrictions that are placed on infected animals and the biological effects of the disease: infertility, dramatic loss in milk production, induction of abortion and mortality. It is caused by lumpy skin disease virus (LSDV), which belongs to the Poxviridae family.

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Vascular endothelial growth factor (VEGF) and its receptor play an important role both in physiologic and pathologic angiogenesis, which is identified in ovarian cancer progression and metastasis development. The aim of the present investigation is to identify a potential vascular endothelial growth factor inhibitor which is playing a crucial role in stimulating the immunosuppressive microenvironment in tumor cells of the ovary and to examine the effectiveness of the identified inhibitor for the treatment of ovarian cancer using various in silico approaches. Twelve established VEGF inhibitors were collected from various literatures.

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Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in children and infants. To date, there is no effective vaccine available against RSV. Heparan sulfate is a type of glycosaminoglycan that aids in the attachment of the RSV to the host cell membrane via the G protein.

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(1) Background: Immune compromised hemodialysis patients are more likely to develop COVID-19 infections, which increase the risk of mortality. The benefits of Remdesivir, despite less literature support on its effectiveness in dialysis patients due to renal toxicity, can outweigh the risks if prescribed early. The aim of this study was to evaluate the efficacy of Remdesivir on the 30-day in-hospital clinical outcome of hemodialysis population with COVID-19 infection and safety endpoints of adverse events.

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Molecular Characterization and Functional Localization of a Novel SUMOylation Gene in .

Biology (Basel)

December 2021

Biotechnology Lab., Plant Production Department, College of Food and Agriculture Sciences, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia.

Article Synopsis
  • A new homolog of SUMO genes was identified in rice, showing its role in post-translational modifications and indicating evolutionary conservation with other rice SUMO genes.
  • Analysis revealed that this SUMO gene is constantly expressed in all plant organs and possesses specific features related to SUMOylation.
  • Experiments demonstrated that the processed OsSUMO7 protein, when fused with a red fluorescent protein, localized primarily in the nucleus and formed distinct nuclear structures, suggesting its involvement in nuclear functions via the SUMOylation system.
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The global burden of disease caused by a respiratory syncytial virus (RSV) is becoming more widely recognized in young children and adults. Heparan sulfate helps in attaching the virion through G protein with the host cell membrane. In this study, we examined the structural changes of ectodomain G protein (edG) in a wide pH range.

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Salinity is one of the largest stresses blocking horizontal and vertical expansion in agricultural lands. Establishing salt-tolerant genotypes is a promising method to benefit from poor water quality and salinized lands. An integrated method was developed for accomplishing reliable and effective evaluation of traits stability of salt-tolerant wheat.

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Molecular detection of Mycobacterium tuberculosis in pulmonary and extrapulmonary samples in a hospital-based study.

Afr Health Sci

December 2020

Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box-10219, Riyadh-11433, Saudi Arabia.

Objective: Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a deadly infectious disease. India contributes to one-third of the global TB burden. However, no studies have been carried out in the Telangana (Hyderabad) population using real-time polymerase chain reaction (RT-PCR).

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Photoperiod and thermosensitive genetic male sterile (PTGMS) lines have become one of the main sources of global rice production increasing. This study was conducted to evaluate the fertility alteration and validate the male sterility genes using validation markers in novel Egyptian and PTGMS lines under natural conditions. The study revealed that the new genetic male sterile lines belong to the type of photo-thermosensitive genetic male sterility (PTGMS).

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The effect of foliar treatment with jasmonic acid at 0.5 mM (JA) and biochar (15 ton ha) as a soil amendment for the faba bean (Vicia faba L. Sakha 4) was studied under salinity conditions.

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Plant growth-promoting bacteria play an essential role in enhancing the physical, chemical and biological characters of soils by facilitating nutrient uptake and water flow, especially under abiotic stress conditions, which are major constrains to agricultural development and production. Drought is one of the most harmful abiotic stress and perhaps the most severe problem facing agricultural sustainability, leading to a severe shortage in crop productivity. Drought affects plant growth by causing hormonal and membrane stability perturbations, nutrient imbalance and physiological disorders.

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Pharmacogenetic determinants of warfarin in the Indian population.

Pharmacol Rep

October 2021

Research Chair for Biomedical Applications of Nanomaterials, Biochemistry Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.

Background: Several studies optimized the warfarin dose based on CYP2C9*2, CYP2C9*3, VKORC1 -1639 G > A, CYP4F2 V433M. But, the information on the rare variants is lacking. In this study, we have explored the prevalence of common and rare pharmacogenetic determinants of warfarin and determined their damaging nature.

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and Silicon Modulate Antioxidant Metabolism and Improve the Physiological Traits to Confer Salt Tolerance in Lettuce.

Plants (Basel)

May 2021

Excellence Center (EPCRS), Plant Pathology and Biotechnology Lab, Faculty of Agriculture, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.

We investigated the impact of as seed treatment and application with silicon on lettuce plants exposed to salinity levels (4 dS m and 8 dS m). Results revealed that leaves number, head weight, total yield, relative water content (RWC), and chlorophyll a and b declined considerably due to two salinity levels. Oxidative stress markers, i.

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Fungicides among agrochemicals are consistently used in high throughput agricultural practices to protect plants from damaging impact of phytopathogens and hence to optimize crop production. However, the negative impact of fungicides on composition and functions of soil microbiota, plants and via food chain, on human health is a matter of grave concern. Considering such agrochemical threats, the present study was undertaken to know that how fungicide-tolerant symbiotic bacterium, Mesorhizobium ciceri affects the Cicer arietinum crop while growing in kitazin (KITZ) stressed soils under greenhouse conditions.

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A broad spectrum of medicinal plants was used as traditional remedies for various infectious diseases. Fungal infectious diseases have a significant impact on public health. Fungi cause more prevalent infections in immunocompromised individuals mainly patients undergoing transplantation related therapies, and malignant cancer treatments.

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The present study describes the biosynthesis of silver nanoparticles, using the fungus . The silver nanoparticles were synthesised by reacting silver nitrate (AgNO) with the cell free filtrates of the fungal culture, and were then characterized by UV-visible spectroscopy, transmission electron microscopy, scanning electron microscopy, energy-dispersive, and X-ray diffraction analysis to further evaluate their successful biosynthesis, optical and morphological features (size and shape), and crystallinity. The bioactivity of the synthesized nanoparticles against two phytopathogenic fungi i.

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Evaluation of Silicon and Proline Application on the Oxidative Machinery in Drought-Stressed Sugar Beet.

Antioxidants (Basel)

March 2021

Excellence Center (EPCRS), Plant Pathology and Biotechnology Lab, Faculty of Agriculture, Kafrelsheikh University, Kafr Elsheikh 33516, Egypt.

Drought stress deleteriously affects growth, development and productivity in plants. So, we examined the silicon effect (2 mmol) and proline (10 mmol) individually or the combination (Si + proline) in alleviating the harmful effect of drought on total phenolic compounds, reactive oxygen species (ROS), chlorophyll concentration and antioxidant enzymes as well as yield parameters of drought-stressed sugar beet plants during 2018/2019 and 2019/2020 seasons. Our findings indicated that the root diameter and length (cm), root and shoot fresh weights (g plant) as well as root and sugar yield significantly decreased in sugar beet plants under drought.

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Article Synopsis
  • This study focuses on the CYP2C19 gene, which affects how some drugs work in the body, specifically in a sample of 2000 healthy Indians.
  • Researchers identified five common variants of CYP2C19, with *2 and *17 being the most prevalent, impacting drug metabolism.
  • The findings suggest that *2 and *3 are less effective for drug metabolism (loss-of-function), while *17 enhances drug action (gain-of-function), indicating their significance for personalized medicine in this population.
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