Dual wavelength irradiation antimicrobial photodynamic therapy using indocyanine green and metformin doped with nano-curcumin as an efficient adjunctive endodontic treatment modality.

Background: Indocyanine green (ICG) doped with nano-curcumin (N-CUR) can increase photosensitivity in antimicrobial photodynamic therapy (aPDT). Since metformin (Met) provides a synergistic advantage with photosensitivity, it was conjugated with N-CUR@ICG. Aim of the study was to evaluate the photosensitizing effect of N-CUR@ICG-Met used as a new photosensitizer in dual wavelengths irradiation (diode laser and light-emitting diode, LED) aPDT in root canals infected with Enterococcus faecalis biofilm.

Evaluation of the outcome of various laser therapy applications in root canal disinfection: A systematic review.

Background: Any successful endodontic therapy requires elimination of the endodontic biofilms through meticulous root canal disinfection methods. Sodium hypochlorite (NaOCl) and ethylenediaminetetraacetic acid (EDTA) are the most common effective irrigants, in removing smear-layer from the coronal and middle thirds of the dental canals but reduced considerably towards the apical one third. In recent years, newly alternative treatment modalities have been proposed, including high-power lasers and antimicrobial photodynamic therapy (aPDT).

Effect of Er:YAG and Er,Cr:YSGG Lasers on Ceramic Bracket Debonding from Composite Blocks.

Objectives: This study aimed to assess the effect of erbium-doped yttrium aluminum garnet (Er:YAG) and erbium, chromium: yttrium, scandium, gallium, garnet (Er,Cr:YSGG) lasers on the shear bond strength (SBS) of ceramic brackets debonding from the surface of composite blocks.

Materials And Methods: Thirty-six composite blocks were fabricated using Filtek Z250 light-cure composite. Block surfaces were etched with 37% phosphoric acid for 30 seconds and then rinsed with water for 20 seconds and dried.

Antimicrobial action of photoactivated C-Phycocyanin against Enterococcus faecalis biofilms: Attenuation of quorum-sensing system.

Background: The limitations of conventional chemo-mechanic therapy in endodontic have given rise to introduce and develop photoactivated disinfection (PAD) as an adjunctive treatment. The objective of this ex vivo study was to evaluate the effects of PAD using C-Phycocyanin, as a natural photosensitizer, on biological activities and expression of quorum-sensing system gene fsrB of Enterococcus faecalis.

Materials And Methods: A total of 52 extracted single-rooted human premolar teeth were divided into five groups (n = 10) and were incubated with E.

Comparison of Canine Overlap in Pediatric Patients Requiring Stainless Steel Crown Placement under General Anesthesia before and after the Procedure.

Objectives: Despite the increasing popularity of pediatric dental treatments under general anesthesia, information is scarce regarding occlusal changes in patients receiving stainless steel crowns (SSCs) under general anesthesia. This study sought to compare canine overlap before and after general anesthesia in children receiving SSCs. In case of a change, the possibility of returning to the preoperative state and the time required for this process were also evaluated.

Evaluation of the Shear Bond Strength and Adhesive Remnant Index in Debonding of Stainless Steel Brackets Assisted with Nd:YAG Laser Irradiation.

Objectives: The purpose was to compare shear bond strength (SBS), pulp temperature, and adhesive remnant index (ARI) in debonding of stainless steel brackets from enamel surface using neodymium-doped yttrium aluminum garnet (Nd:YAG) laser versus the conventional debonding method.

Materials And Methods: Forty-eight extracted premolars were bonded to stainless steel brackets. The samples were divided into three experimental groups and one control group.

Comparison of Microleakage of Pedo Jacket Crowns and Stainless Steel Crowns Cemented with Different Cements.

Objectives: This study aimed to assess the microleakage of Pedo Jacket crowns compared to stainless steel crowns (SSCs) cemented with different luting cements.

Materials And Methods: In this in-vitro experimental study, 80 primary molars were randomly divided into four groups of 20 each. Groups 1 and 2 were subjected to standard tooth preparation for SSC.

Comparative evaluation of the effects of different methods of post space preparation in primary anterior teeth on the fracture resistance of tooth restorations.

Severely damaged teeth do not have adequate structure to support the composite crown; therefore, use of the canal space has been suggested to increase retention. Furthermore, the effect of post space irrigation protocols on the fracture resistance of the primary anterior teeth has not definitely been studied in postoperative modalities. This study compared the fracture resistance of restorations of primary anterior teeth following irrigation of the post space with sodium hypochlorite and chlorhexidine with and without application of burs.

Early-predictors of marginal bone loss around morse taper connection implants loaded with single crowns: A prospective longitudinal study.

Background And Objective: Few studies estimated the joint effect of implant design (length and diameter), peri-implant, and occlusal variables on early marginal bone loss. The monitoring of these factors during the first year after implant loading may be effective in preventing early implant failure. This prospective longitudinal study aimed to identify early-predictors of marginal bone loss around morse-tapered connection implants 12 months after implant loading.

Oral adverse effects of drugs: Taste disorders.

Objective: Oral healthcare professionals are frequently confronted with patients using drugs on a daily basis. These drugs can cause taste disorders as adverse effect. The literature that discusses drug-induced taste disorders is fragmented.

Photoexcitation triggering via semiconductor Graphene Quantum Dots by photochemical doping with Curcumin versus perio-pathogens mixed biofilms.

Background: Recently, antimicrobial photodynamic therapy (aPDT) as an alternative treatment modality has been used adjunctively in the treatment of periodontitis and peri-implantitis. Photosensitizing agents in the form of nanoparticles have been designed for improving the efficiency of aPTD. Graphene quantum dots are a special type of nanocrystals that can promote aPDT when coupled with curcumin (Cur).

Assessment of photobiomodulation therapy by an 8l0-nm diode laser on the reversal of soft tissue local anesthesia in pediatric dentistry: a preliminary randomized clinical trial.

During the injection of local anesthesia in pediatric dental procedures, from the injection time until the elimination of tissue anesthesia, inevitable problems were reported. According to the encouraging results of previous studies addressing the positive effects of laser therapy on increasing the microcirculation, we aimed to investigate the clinical effect of photobiomodulation therapy on the reversal of soft tissue anesthesia in children. Using a split-mouth design, 34 children aged 4 to 8 years old, candidate for receiving local infiltration injection at both right and left side in mandible, were enrolled in the study.

Efficacy of antimicrobial photodynamic therapy for elimination of Aggregatibacter actinomycetemcomitans biofilm on Laser-Lok titanium discs.

Background: Antimicrobial Photodynamic therapy (aPDT) is a novel modality suggested for treatment of peri-implantitis. This study aimed to assess the effect of aPDT with toluidine blue (TBO) and indocyanine green (ICG) and 635 nm and 808 nm diode laser on Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) biofilm formed on Laser-Lok titanium discs.

Effect of Er: YAG Laser on Microtensile Bond Strength of Bleached Dentin to Composite.

In non-vital tooth bleaching, dentin is in direct contact with the bleaching agent, 1 to 3-week delay is needed to eliminate free radicals from tooth structure. The present study aimed to evaluate the effect of irradiation of Er: YAG laser on immediate microtensile bond strength of bleached dentin to composite. Sixty sounds human teeth were collected and randomly divided into 4 groups (n=15): no bleaching (NB), opalescence endo hydrogen peroxide (HP) gel bleaching, sodium perborate (SP) bleaching and laser bleaching with heydent gel (LB).

Laser Aided Ceramic Restoration Removal: A Comprehensive Review.

All-ceramic restorations are being widely used due to its various advantages. However, they have restricted durability and may have to be removed. The conventional procedure for removal is grinding the restoration with rotary instruments which are considered time-consuming and inconvenient.

Modulation of Toxin-Antitoxin System Rnl AB Type II in Phage-Resistant Gammaproteobacteria Surviving Photodynamic Treatment.

Type II toxin-antitoxin (TA) systems are the particular type of TA modules which take part in different kinds of cellular actions, such as biofilm formation, persistence, stress endurance, defense of the bacterial cell against multiple phage attacks, plasmid maintenance, and programmed cell death in favor of bacterial population. Although several bioinformatics and Pet lab studies have already been conducted to understand the functionality of already discovered TA systems, still, more work in this area is required. Rnl AB type II TA module, which is composed of RnlA toxin and RnlB antitoxin, is a newly discovered type II TA module which takes part in the defense mechanism against T4 bacteriophage attack in Escherichia coli K-12 strain MH1 that has not been widely studied in other bacteria.

Bacterial biofilm composition in healthy subjects with and without caries experience.

The composition of the oral microbiome differs distinctively between subjects with and without active caries. Still, caries research has mainly been focused on states of disease; aspects about how biofilm composition and structure maintain oral health still remain widely unclear. Therefore, the aim of the study was to compare the healthy oral microbiome of caries-free adult subjects with and without former caries experience using next generation sequencing methods.

Stabilizing mandibular complete dentures by a single midline implant-influence on quality of life: 2-year results from a randomized clinical trial comparing different loading protocols.

Objectives: The knowledge about the influence of dental treatment on health-related quality of life (HRQoL) is still limited. The aim of this multicenter randomized controlled clinical trial was to assess the effect of stabilizing an existing complete denture, by means of a single mandibular implant, on HRQoL. Furthermore, the impact of the loading protocol, i.

Influence of craniocervical and craniomandibular dysfunction to nonrestorative sleep and sleep disorders.

: Nonrestorative sleep and sleep disorders are commonly reported in patients suffering from craniomandibular (CMD) and craniocervical dysfunctions (CCD). This study aimed to investigate polysomnographic characteristics and the reduction of pain before and after treatment in these patients.: Seventy-four patients with sleep disorders and evident CMD and CCD were included.

Effect of ultrasonic activation on the efficacy of antimicrobial photodynamic therapy: Evaluation of penetration depth of photosensitizer and elimination of Enterococcus faecalis biofilms.

Background: This study aimed to assess the effect of ultrasonic activation of photosensitizer on the efficacy of Antimicrobial Photodynamic Therapy (aPDT) against Enterococcus faecalis and penetration depth of photosensitizer.

Materials And Methods: In this ex vivo study, mature microbial biofilm of E. faecalis was formed in the root canals of 58 single-rooted single-canal mandibular incisors following their decoronation.

The Esthetic Crown Lengthening by Er;Cr:YSGG laser: A Case Series.

Laser technology as a new modality in dentistry has gained special attention. Among different types of lasers, erbium lasers have gained special attention for management of oral soft and hard tissue simultaneously. This study presents series of cases of crown lengthening (CL) and restorations accomplished by erbium, chromium: yttrium-scandium-gallium-garnet (Er,Cr:YSGG).

Comparison of the Effects of Er, Cr: YSGG Laser and Super-Saturated Citric Acid on the Debridement of Contaminated Implant Surfaces.

Several techniques such as using citric acid, plastic curettes, ultrasonic devices, and lasers have been suggested for debridement of contaminated implant surfaces. This comparative investigation aimed to assess and compare the effects of Er, Cr: YSGG laser and super-saturated citric acid on the debridement of contaminated dental implant surfaces. In this in-vitro study, 12 contaminated failed implants were collected and randomly divided into 2 groups (6 in group A, and 6 in group B).

Thermal Changes in Root Surface of Primary Teeth During Root Canal Treatment With Diode Lasers: An In Vitro Study.

Increased temperature due to the application of laser during root canal disinfection may damage periodontium, alveolar bone, and permanent dental germ. The aim of this study was to evaluate the temperature increase of the external surface of primary roots due to the application of 810 nm and 980 nm diode lasers. A total of 58 extracted human primary teeth were prepared and randomly divided into two groups: (a) 810 nm diode laser and (b) 980 nm diode laser.

Likelihood of needing facial bone augmentation in the anterior maxilla of Chinese Asians: A cone beam computed tomography virtual implant study.

Background: The perfect position and axis of an implant is often limited by the morphology of the alveolar ridge, especially in Asians.

Purpose: The aim of this study was to investigate the frequency at which ideal implant placement position in the anterior maxilla of Chinese Asians would require facial bone augmentation given by an initial facial bone profile.

Materials And Methods: Implants were virtually placed in 303 sites without tooth loss in the anterior maxilla.