Implementation of an advanced practice role for oxygen prescription by physiotherapists in pulmonary rehabilitation: an explanatory sequential mixed-method quality evaluation.

Background: Physiotherapists play a key role in the administration of supplemental oxygen during physical activity in pulmonary rehabilitation. However, supplemental oxygen requires a medical prescription making processes cumbersome for physiotherapists. This study aimed to implement and evaluate an advanced practice role for physiotherapists (APO) allowing them to prescribe oxygen during physical activity.

Arm weight effects on dynamic walking stability in individuals with hemiparetic stroke.

This study examined the effects of arm weights on dynamic stability during overground walking in individuals with hemiparetic stroke. Arm weights have been shown to improve mobility in stroke survivors, potentially at the cost of decreased dynamic stability and increased fall risk. Data from nine stroke survivors (8 males, 1 female; age: 58.

Bibliometric analysis of global research on vitamins and cancer between 2003 and 2022.

Background: Vitamins are essential nutrients that play an indispensable role in maintaining the vital functions of the human body. A growing number of studies have shown a link between vitamins and cancer. However, there is no systematic review and bibliometric analysis in this field.

Ultrasonography for Assessment and Intervention With Botulinum Toxin Injection for Tremors.

Objective: Tremors are caused by contractions of reciprocally innervated muscles. The role of ultrasound in diagnosing tremors has not yet been investigated, although it appears to be promising because it can visualize muscle movements. In the present study, we report four cases of tremor (Holmes' tremor, extremity tremor associated with palatal myoclonus, dystonic tremor, and tremor associated with dystonia), which were evaluated using ultrasound and treated with botulinum toxin injections.

Clinical observation of 4 cases of cerebral infarction caused by left ventricular noncompaction.

Background: Cerebral infarction associated with myocardial hypertrabeculation is a rare condition that requires optimal management to reduce the risk of thromboembolism and stroke. As intravenous thrombolysis (IVT) is a standard treatment for acute ischemic stroke, it is important to investigate whether it is safe and effective in patients with this rare condition.

Case Report: Four patients with cerebral infarction associated with myocardial hypertrabeculation were included.

Luminol/PtCo@rGO and Au@CNTs-based electrochemiluminescence cytosensor for ultrasensitive detection of breast cancer CTCs.

Background: Breast cancer CTCs have recently been recognized as an emerging biomarker for liquid biopsy of breast cancer. In this work, based on two-dimensional (2D) noble metal PtCo@rGO nanozymes and Au@CNTs bioconjugates, a novel electrochemiluminescence (ECL) cytosensor was developed in order to detect breast cancer CTCs (MCF-7) ultrasensitively.

Results: The PtCo@rGO nanozymes possessed large specific surface area and high efficiency peroxidase-like activity, which can be used as nanocarriers to anchor and catalyze luminol ECL emission efficiently.

Effectiveness of unilateral lower-limb exoskeleton robot on balance and gait recovery and neuroplasticity in patients with subacute stroke: a randomized controlled trial.

Background: Impaired balance and gait in stroke survivors are associated with decreased functional independence. This study aimed to evaluate the effectiveness of unilateral lower-limb exoskeleton robot-assisted overground gait training compared with conventional treatment and to explore the relationship between neuroplastic changes and motor function recovery in subacute stroke patients.

Methods: In this randomized, single-blind clinical trial, 40 patients with subacute stroke were recruited and randomly assigned to either a robot-assisted training (RT) group or a conventional training (CT) group.

The Therapeutic Potential of Pristimerin in Osteoarthritis: Mechanistic Insights from in vitro and in vivo Studies.

Objective: Osteoarthritis (OA), a degenerative disease marked by cartilage erosion and synovial proliferation, has led to an increased interest in natural plant-based compounds to slow its progression. Pristimerin(Pri), a triterpenoid compound derived from Tripterygium wilfordii, has demonstrated anti-inflammatory and antioxidant characteristics. This study explores the protective effects of Pri on OA and its potential mechanisms.

Efficacy of melatonin for prolonged disorders of consciousness: a double-blind, randomized clinical trial.

Background: Sleep is essential for the recovery of patients with disorders of consciousness (DoC). However, few approaches targeting sleep were applied. Melatonin has been shown to enhance sleep efficiency with virtually no side effects.

Determinants of sustainable work participation after spinal cord injury in The Netherlands.

Purpose: Work participation of persons with spinal cord injury (SCI) is lower compared to the overall Dutch population, with determinants largely unknown.

Aim: To identify the determinants of sustainable work participation for persons with SCI.

Methods: A cross-sectional multicenter study was conducted in eight Dutch rehabilitation centers.

Marein ameliorates the progression of osteoarthritis: An in vitro and in vivo studies.

Osteoarthritis (OA) is a prevalent, degenerative joint disease that requires effective treatments to prevent its progression. Therefore, the development of novel therapeutic strategies to address this unmet clinical challenge is paramount. Marein (MA), the principal active compound of Coreopsis tinctoria Nutt, exhibits anti-inflammatory and anti-oxidant properties in various diseases, indicating its potential as a therapeutic agent for OA.

Assessment of rehabilitation treatment for patients with acute poisoning-induced toxic encephalopathy.

Background: Poisoned patients often suffer damage to multiple systems, and those experiencing central nervous system disorders present more severe conditions, prolonged hospital stays, and increased mortality rates. We aimed to assess the efficacy of rehabilitation interventions for patients with toxic encephalopathy.

Methods: This retrospective, observational, comparative cohort study was performed at the teaching hospital affiliated of Nanjing Medical University, from October 2020 to December 2022.

Phenotypic Variability in Camurati-Engelmann Disease: A Case Report of a Family with the c.653G>A Pathogenic Variant in the Gene.

Camurati-Engelmann Disease (CED), or Progressive Diaphyseal Dysplasia, is a rare autosomal dominant disorder caused by heterozygous mutations in the Gene, essential for bone regeneration. This study examines the genotype-phenotype relationship in a family diagnosed with CED, specifically focusing on a missense variant (c.653G>A, p.

Exploring perspectives on implementing the World Health Assembly's Resolution for Strengthening Rehabilitation in Health Systems in Switzerland: a representative rehabilitation stakeholder survey.

Purpose: In 2023, the World Health Assembly endorsed a Resolution on Strengthening Rehabilitation in Health Systems. This study aims to explore the perspectives of Swiss rehabilitation stakeholders regarding the relevance, challenges, and opportunities of the Resolution for Switzerland.

Methods: A cross-sectional online survey was conducted among Swiss rehabilitation stakeholders.

Demographic and Socioeconomic Disparities in Adolescent Obesity: Insights From the National Survey of Children's Health Database.

Background:  Obesity among adolescents is a significant public health concern. This study analyzes the prevalence of obesity among adolescents using data from the National Survey of Children's Health (NSCH). The analysis focuses on the impact of race and socioeconomic variables on obesity rates.

Test-Retest Reliability and Agreement of the Work Ability Index-Single Item in Persons With Physical Disabilities.

Objective: To assess the test-retest reliability and agreement of the work ability index-single item (WAS) in persons with a physical disability.

Design: Test-retest study, with a 2-4 week interval. Test-retest reliability was computed using the intraclass correlation coefficient (ICC).

Chest computed tomography for patients with sepsis in the emergency intensive care unit.

Sepsis is a systemic inflammatory response syndrome (SIRS) caused by infection, which may lead to multiple organ dysfunction in susceptible patient. The most frequently involved organs/systems include the lung, kidney and circulation system. It is well established that sepsis is a risk factor for acute lung injury.

The Relationship Between BigET-1 and Cardiac Remodeling in Patients with Hypertrophic Obstructive Cardiomyopathy.

To explore the relationship between BigET-1 and cardiac remodeling in hypertrophic obstructive cardiomyopathy (HOCM). A retrospective analysis was conducted on the data of 150 HOCM patients in a hospital from September 2021 to August 2023. According to the 2015 American Ultrasound Society's recommended standards for quantifying adult UGG cardiac lumen, left atrial enlargement is defined as having a left atrial diameter greater than 40 mm in males and greater than 38 mm in females.

Evaluating Docking Site Local Hematoma Formation and Blood Flow on its Healing Using the Accordion Technique at the End of Tibial Bone Transport.

Objective: At present, due to the lack of early observation methods, the effect of the 'accordion' technique on the treatment of nonunion of the docking site varies greatly. In this study, color Doppler ultrasound was used to observe the docking site's local changes and investigate the relationship between local microenvironment changes and bone healing after the accordion technique.

Methods: 30 patients with tibial bone transport treated at the Department of Orthopedics, Second Hospital of Shanxi Medical University, from May 2018 to June 2022, were analyzed retrospectively.