Impact of Chronic Consumption of Herbal Rooibos on Cardiovascular Function in Adults with Cardiovascular Risk.

The prevalence of cardiovascular disease (CVD) has increased in South Africa, emphasizing the importance of prevention strategies. This study used echocardiography to investigate the impact of Rooibos on cardiovascular function in those at risk of CVD. This research aims to contribute to understanding its effects on reducing cardiovascular risk factors.

Voices of Change: Stakeholders' Roles in the Fight Against Substance Abuse in Mogadishu, Somalia.

Aim: This study explores the roles, challenges, and collaborative efforts of key stakeholders engaged in addressing substance abuse.

Methods: Using a qualitative narrative approach, the study examined stakeholder roles in tackling substance abuse in Mogadishu, Somalia. Purposive sampling was utilised to select all available community stakeholders actively addressing substance abuse.

Gastro-intestinal parasites of urban rhesus macaques () in the Kathmandu Valley, Nepal.

Intestinal parasitic infections such as amoebiasis, ascariasis, hookworm infection, and are the most common infections among non-human primates (NHPs). There are always the possibilities of transmission these parasites between humans and NHPs. Multiple groups of rhesus macaques () live in the urban area of Kathmandu Valley near human settlements, however the gastrointestinal (GI) parasitic infections in those macaques are understudied.

Sequence Analysis of Novel Lineages from Wild and Captive Macaques.

is a widespread and common opportunistic bacterium that can colonise or infect humans as well as a wide range of animals. There are a few studies of both methicillin-susceptible (MSSA) and methicillin-resistant (MRSA) isolated from monkeys, apes, and lemurs, indicating a presence of a number of poorly or unknown lineages of the pathogen. In order to obtain insight into staphylococcal diversity, we sequenced strains from wild and captive individuals of three macaque species (, , and ) using Nanopore and Illumina technologies.

Silk Fiber Multiwalled Carbon Nanotube-Based Micro-/Nanofiber Composite as a Conductive Fiber and a Force Sensor.

Silk cocoon fibers (SFs) are natural polymers that are made up of fibroin protein. These natural fibers have higher mechanical stability and good elasticity properties. In this work, we coated multiwalled carbon nanotubes (MWCNTs) on the surface of SFs using a simple stirring technique with vinegar as the medium.

Pd on Guanidine-Functionalized FeO Nanoparticles as an Efficient Heterogeneous Catalyst for Suzuki-Miyaura Cross-Coupling and Reduction of Nitroarenes in Aqueous Media.

This paper presents guanidine-functionalized FeO magnetic nanoparticle-supported palladium (II) (FeO@Guanidine-Pd) as an effective catalyst for Suzuki-Miyaura cross-coupling of aryl halides using phenylboronic acids and also for selective reduction of nitroarenes to their corresponding amines. FeO@Guanidine-Pd synthesized is well characterized using FT-IR spectroscopy, XRD, SEM, TEM, EDX, thermal gravimetric analysis, XPS, inductively coupled plasma-optical emission spectroscopy, and vibrating sample magnetometry analysis. The prepared FeO@Guanidine-Pd showed effective catalytic performance in the Suzuki-Miyaura coupling reactions by converting aryl halides to their corresponding biaryl derivatives in an aqueous environment in a shorter reaction time and with a meagerly small amount of catalyst (0.

Role of vitamins in the metabolic syndrome and cardiovascular disease.

The prevalence of metabolic syndrome and cardiovascular disease has increased and continues to be the leading cause of mortality worldwide. The etiology of these diseases includes a complex phenotype derived from interactions between genetic, environmental, and nutritional factors. In this regard, it is common to observe vitamin deficiencies in the general population and even more in patients with cardiometabolic diseases due to different factors.

The geography of femicide in Sergipe, Brazil: matriarchy, human development, and income distribution.

Aim: This research analyzed a joint spatial distribution and explored the possible associations between epidemiological aspects and feminicide rates, in towns of the Sergipe State in Northeastern Brazil.

Methodology: An exploratory ecological study investigated the global spatial autocorrelation of epidemiological aspects with femicide rates from towns in Sergipe State, Brazil, (n = 75), in the 2013-2017 period, using the "global" and "local" Moran statistic method and a multiple spatial regression. The exposure variables included socioeconomic and demographic conditions, services and health condition, and femicide rates.

and Methicillin Resistant in Nepalese Primates: Resistance to Antimicrobials, Virulence, and Genetic Lineages.

is a ubiquitous pathogen and colonizer in humans and animals. There are few studies on the molecular epidemiology of in wild monkeys and apes. carriage in rhesus macaques () and Assam macaques () is a species that has not previously been sampled and lives in remote environments with limited human contact.

Correction to: Indian sarsaparilla, Hemidesmus indicus (L.) R. Br. ex Schult: tissue culture studies.

Following publication of the original article (Kher et al. 2020), the authors identified following mistake in the author affiliation.

Validity and reliability of the kiddie schedule for affective disorders and schizophrenia present and lifetime version DSM-5 (K-SADS-PL-5) Spanish version.

Background: There are various language adaptations of the Schedule for Affective Disorders and Schizophrenia for School Age Children Present and Lifetime Version (K-SADS-PL). In order to comply with the changes in DSM classification, the Spanish edition of the interview was in need of update and evaluation.

Methods: K-SADS-PL was adapted to correspond to DSM-5 categories.

Enhanced micropollutant biodegradation and assessment of nitrous oxide concentration reduction in wastewater treated by acclimatized sludge bioaugmentation.

This research investigated the micropollutant biodegradation and nitrous oxide (NO) concentration reduction in high strength wastewater treated by two-stage activated sludge (AS) systems with (bioaugmented) and without (non-bioaugmented) acclimatized sludge bioaugmentation. The bioaugmented and non-bioaugmented systems were operated in parallel for 228 days, with three levels of concentrations of organics, nitrogen, and micropollutants in the influent: conditions 1 (low), 2 (moderate), and 3 (high). The results showed that, under condition 1, both systems efficiently removed the organic and nitrogen compounds.

The human clone ST22 SCCmec IV methicillin-resistant Staphylococcus aureus isolated from swine herds and wild primates in Nepal: is man the common source?

Swine nasal samples [n = 282] were collected from 12 randomly selected farms around Kathmandu, Nepal, from healthy animals. In addition, wild monkey (Macaca mulatta) saliva samples [n = 59] were collected near temples areas in Kathmandu using a non-invasive sampling technique. All samples were processed for MRSA using standardized selective media and conventional biochemical tests.

Synthesis, anti-angiogenic and DNA cleavage studies of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives.

A series of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives 10(a-f), 12(a-c) and 14(a-c) were synthesized and characterized by FTIR, H-NMR, mass spectral and elemental analysis. The efficacy of these derivatives to inhibit in vivo angiogenesis was evaluated using chick chorioallantoic membrane (CAM) model and their DNA cleavage abilities were evaluated after incubating with calf thymus DNA followed by gel electrophoresis. These novel piperidine analogues efficiently blocked the formation of blood vessels in vivo in CAM model and exhibited differential migration and band intensities in DNA binding/cleavage assays.

Dissipation of spiromesifen and spiromesifen-enol on tomato fruit, tomato leaf, and soil under field and controlled environmental conditions.

Dissipation of spiromesifen and its metabolite, spiromesifen-enol, on tomato fruit, tomato leaf, and soil was studied in the open field and controlled environmental conditions. Sample preparation was carried out by QuEChERS method and analysis using LC-MS/MS. Method validation for analysis of the compounds was carried out as per "single laboratory method validation guidelines.

Effect of total solids content on biohydrogen production and lactic acid accumulation during dark fermentation of organic waste biomass.

Production of biohydrogen and related metabolic by-products was investigated in Solid State Dark Fermentation (SSDF) of food waste (FW) and wheat straw (WS). The effect of the total solids (TS) content and H partial pressure (pp), two of the main operating factors of SSDF, were investigated. Batch tests with FW at 10, 15, 20, 25 and 30% TS showed considerable effects of the TS on metabolites distribution.

A Benzothiazole Derivative (5g) Induces DNA Damage And Potent G2/M Arrest In Cancer Cells.

Chemically synthesized small molecules play important role in anticancer therapy. Several chemical compounds have been reported to damage the DNA, either directly or indirectly slowing down the cancer cell progression by causing a cell cycle arrest. Direct or indirect reactive oxygen species formation causes DNA damage leading to cell cycle arrest and subsequent cell death.

Synthesis, Characterization of 4-Anilino-6,7-Dimethoxy Quinazoline Derivatives as Potential Anti-Angiogenic Agents.

Background: Quinazolines are a big family of heterocyclic compounds with anti-cancer properties.

Objective: The latest investigation was on synthesis, characterization of novel 4-anilinoquinazoline derivatives for their anti-angiogenic effect.

Method: A series of novel 4-anilino-6,7-dimethoxy quinazoline derivatives were synthesized and characterized using 1H, 13C NMR, FT-IR and LC-MS techniques.

Dissipation pattern of flubendiamide residues on capsicum fruit (Capsicum annuum L.) under field and controlled environmental conditions.

This investigation was undertaken to compare the dissipation pattern of flubendiamide in capsicum fruits under poly-house and open field after giving spray applications at the recommended and double doses of 48 g a.i. ha(-1) and 96 g a.

Statistical optimization of synthetic azo dye (orange II) degradation by azoreductase from Pseudomonas oleovorans PAMD_1.

Pseudomonas oleovorans PAMD_1 produced an intracellular azoreductase as the more prominent enzyme that reduces the azo bridge during the azo dye decolorization process. In order to optimize the expression of azoreductase, statistically based experiments were applied. Eleven significant factors were screened on decolorization activity using Plackett-Burman design.

Molecular modeling of 2-nitropropane dioxygenase domain of Mycobacterium tuberculosis H37Rv and docking of herbal ligands.

The 3D structure of enoyl reductase (ER) domain generated by the SWISS MODEL server contains the 2-nitropropane dioxygenase (2NPD) structure displaying the TIM barrel fold. Though TIM barrel fold is made up of both main and inserted domains, in our study, we could only predict the structure of the main domain, which had central barrel of eight beta-strands surrounded by eight alpha-helices. Superimposition of the 2NPD region of ER domain of Mycobacterium tuberculosis H37Rv on to the corresponding region of 2UVA_G revealed a good structural alignment between the two, suggesting this template to be a good structural homologue.