Treatment of a symptomatic patient with severe progressive odontoid invagination and Cervicothoracic scoliosis: A case report.

While there is no consensus on optimal treatment management for the rare condition of odontoid invagination with cervicothoracic scoliosis, skull traction for 12 weeks followed by combined posterior and anterior spinal fusion can be a feasible option. However, surgeons should be prepared for significant intraoperative and postoperative challenges.

Use of an ultrasound-based navigation system for an accurate acetabular positioning in total hip arthroplasty: a prospective, randomized, controlled study.

The purpose of this study was to compare an ultrasound-based navigation system with an imageless navigation system with surface registration in the postoperative acetabular cup position. A prospective randomized controlled study of 2 groups of 40 patients each was performed. In the first group, cup positioning was assisted by an ultrasound-based navigation system, and in the second group, the cup was assisted by imageless navigation system with surface registration.

Validation of a CT image based software for three-dimensional measurement of acetabular cup orientation.

The purpose of our study was to develop a simple and reproducible method for calculating post-operative acetabular cup position based upon computed tomographic images. Next, we sought to examine the reliability, objectivity and accuracy of this method. We developed a 3D CT evaluation software based upon Amira® (data visualisation, analysis and modelling software) to calculate the abduction and anteversion of the acetabular cup relative to the APP (anterior pelvic plane).

Insights into mesenchymal stem cell aging: involvement of antioxidant defense and actin cytoskeleton.

Progenitor cells such as mesenchymal stem cells (MSCs) have elicited great hopes for therapeutic augmentation of physiological regeneration processes, e.g., for bone fracture healing.

A new device to control mechanical environment in bone defect healing in rats.

Mechanical conditions have a significant influence on the biological processes of bone healing. Small animal models that allow controlling the mechanical environment of fracture and bone defect healing are needed. The aim of this study was to develop a new animal model that allows to reliably control the mechanical environment in fracture and bone defect healing in rats using different implant materials.

Influence of age and mechanical stability on bone defect healing: age reverses mechanical effects.

Non-unions and delayed healing are still prevalent complications in fracture and bone defect healing. Both mechanical stability and age are known to influence this process. However, it remains unclear which factor dominates and how they interact.