1,564 results match your criteria: "Center for Medical Education[Affiliation]"

Background The growing emphasis on improving patient safety over the past two decades has received more focus in the undergraduate curricula, and the appropriate assessment of patient safety competencies at graduation is crucial in competency-based medical education. However, there is no valid method for assessing patient safety competencies because current assessment methods in medical education focus less on behavior. The objective structured clinical examination (OSCE) is a method to assess clinical performance and has been implemented by medical schools in Japan for summative assessment at graduation.

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Culturally-aligned clinical leadership competencies for effective teamwork in Japanese healthcare.

BMC Med Educ

November 2024

Center for Medical Education and Career Development, Fukushima Medical University, 1 Hikarigaoka, Fukushima, Fukushima, 960-1295, Japan.

Background: Clinical leadership competencies for effective teamwork differ between Western cultures, where an independent self-construal prevails, and Japanese society, where the self-construal is rooted in interdependence. Although 27 out of 82 Japanese medical schools have 'leadership' as an educational outcome, specific competencies are poorly described, hindering the development of contextually-relevant leadership education. This study aimed to identify clinical leadership competencies and articulate the attributes and skills fundamental to leadership as perceived by Japanese physicians.

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Objective: To identify generalism-related competencies that medical students in Japan should acquire in order to provide comprehensive care for patients.

Methods: The team responsible for developing the new 'Generalism' section of the 2022 revision of the Model Core Curriculum for Medical Education in Japan (MCC) consisted of nine members from diverse medical backgrounds across Japan. We adopted pragmatism paradigm and analyzed to identify decision-making processes using a qualitative document analysis.

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In response to the growing expectation and recognized potential for integrating information and communication technology (ICT) into medicine, the Model Core Curriculum for Medical Education in Japan incorporated 'the ability to use information science and technology' as a new competency in its 2022 revision. This study aimed to identify specific learning objectives that medical students should achieve to acquire this competency. The research team developed an initial list of 107 learning objectives through a literature survey.

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Purpose: This study examines the impact of the 2010 and 2016 Model Core Curriculum (MCC) revisions on medical education across all 82 medical schools in Japan.

Methods: A cross-sectional survey was conducted in 2021, focusing on the response to the MCC revisions, curriculum changes, and factors influencing these changes. The survey included questions on approaches to implementing the MCC revisions, timing of curriculum updates, factors triggering these revisions, changes in student performance and career paths, and the introduction of new subjects.

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Development of a competency-based national model core curriculum in Japan: A case study.

Med Teach

September 2024

Center for Medical Education, Graduate School of Medicine, Nagoya University, Showa-ku, Nagoya, Japan.

Purpose: The 2022 revision of the Model Core Curriculum (MCC) for Japanese undergraduate medical education aimed to develop a stratified, national-level competency framework. This paper aims to explore what innovations emerge during the process of competency-based medical education (CBME) glocalisation, driven by the interplay between global and local language and the dynamics among multiple stakeholders.

Methods: This is an explanatory, retrospective, single-case study with a mixed-methods approach, combining document review and participant reflections.

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Medical education in Japan.

Med Teach

September 2024

Center for Medical Education, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Currently, there are 82 medical schools in Japan. The combined enrollment capacity of medical schools nationwide stands at 9,217. Students are eligible to enter medical school upon graduation from senior high school.

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Background: Discrepancies existed between the medical knowledge sections of the Model Core Curriculum for Medical Education (MCC) and the Guidelines for the National Examination for Medical Practitioners (GNEMP) in Japan. These discrepancies have been one of the underlying factors hindering the development of learner-centered medical education in the country. The project team responsible for the 'Problem-Solving' section of the MCC aimed to address discrepancies between the disease lists in the MCC and the GNEMP.

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Article Synopsis
  • * Seventeen otolaryngologists performed Endoscopic Sinus Surgery (ESS) on both 3D-printed models and cadavers, with their performance evaluated using the Objective Structured Assessment of Technical Skills (OSATS) and the time taken for procedures.
  • * Results showed no significant differences in surgical scores and performance time between the two groups, indicating that 3D models are a viable and sustainable alternative for assessing surgical skills in ESS.
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Article Synopsis
  • The noncanonical TCA cycle is crucial for the energy needs of aggressive cancer cells, relying on mitochondrial oxidative phosphorylation (OXPHOS).
  • Inhibiting ATP-citrate lyase (ACLY), an important enzyme in this cycle, triggers cell death by increasing harmful reactive oxygen species and damaging DNA, while also disrupting the mitochondrial membrane potential.
  • The research suggests a positive feedback mechanism between ACLY and the mitochondrial citrate transporter, indicating that targeting these pathways could impair ATP production and highlight the delicate balance between energy supply and oxidative stress in cancer cells.
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Article Synopsis
  • The CheckMate-743 trial showed that nivolumab plus ipilimumab improves overall survival in patients with unresectable pleural mesothelioma compared to chemotherapy, but lacked representation of Latin American patients.
  • A retrospective study evaluated this treatment's effectiveness and safety in 96 LATAM patients, focusing on their demographic and clinical characteristics, with a median follow-up of 24.1 months.
  • Results indicated median progression-free survival of 8 months and overall survival of 22 months, confirming treatment benefits similar to other findings, with manageable adverse events reported.
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"GME Around the World": Introducing JGME's New Section for International Perspectives in Graduate Medical Education.

J Grad Med Educ

October 2024

is Professor of Medical Education, Dieter Scheffner Center for Medical Education and Educational Research, Dean's Office of Study Affairs, Charité-Universitätsmedizin, Berlin, Germany, and Associate Editor, JGME, Chicago, Illinois, USA.

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Background: Addressing the challenge of cancer control requires a comprehensive, integrated, and global health-system response. We aimed to estimate global radiotherapy demands and requirements for radiotherapy professionals from 2022 to 2050.

Methods: We conducted a population-based study using data from the Global Cancer Observatory (GLOBOCAN) 2022 and predicted global radiotherapy demands and workforce requirements in 2050.

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Article Synopsis
  • Glioblastoma stem cells (GSCs) contribute to the aggressive nature of glioblastoma by making the tumor resistant to therapies, and high levels of γ-Glutamylcyclotransferase (GGCT) are linked to this resistance.
  • Inhibition of GGCT reduces GSC proliferation, and its expression is regulated by the protein c-Jun, which is influenced by the NRas protein.
  • GGCT knockdown not only hampers GSC growth but also disrupts the Delta-Notch signaling pathway by lowering Notch1 levels, suggesting GGCT is a promising target for new glioblastoma treatments.
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Manual flagging failed to identify pseudohyperkalemia in acute myeloid leukemia: case report.

Int J Emerg Med

October 2024

Division of Nephrology, Department of Internal Medicine, UCSF Fresno Center for Medical Education and Research, 155 N Fresno St, Fresno, CA, 93701, USA.

Article Synopsis
  • Pseudohyperkalemia, often seen in chronic lymphocytic leukemia, is rare in acute myeloid leukemia (AML), but can pose diagnostic challenges, as shown in a case involving a 55-year-old man with severe leukocytosis and falsely elevated potassium levels.
  • Despite the lab's manual flagging system meant to identify such cases, it failed to function properly, leading to reliance on clinicians' instincts for the correct diagnosis of pseudohyperkalemia.
  • The incident was linked to pneumatic tube transport of blood samples, prompting the lab to consider enhancements in its flagging system and the importance of using whole blood for potassium measurements in cases of significant leukocytosis.
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Ovarian cancer (OvCa) is one of the most lethal gynecological malignancies, and most patients are diagnosed at advanced stage with peritoneal dissemination. Although age at diagnosis is considered an independent prognostic factor, its impact on peritoneal recurrence after combined cytoreductive surgery and chemotherapy is not clear. The objective of this study was to investigate the impact of aging on peritoneal recurrence from stealth dissemination and gain insight of the pathophysiology of OvCa in elderly patients.

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Background: The global migration of health professionals in general and nurses in particular, has led to nursing shortages and socioeconomic impacts on health systems in both source and destination countries. Adding to the complexity of the situation is the fact that the nursing profession itself is evolving from a vocational to an academic one. Although nursing migration and academization have been studied from either an institutional or an individual perspective, there is a gap in the literature regarding how nursing teams experience these transitions.

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Article Synopsis
  • ZEB1 is a crucial factor in cancer cell behavior, particularly in differentiation and metastasis, while the role of ZEB2 in head and neck squamous cell carcinoma (HNSCC) is less understood.
  • In experiments with mouse oral cancer (MOC) cells, both ZEB1 and ZEB2 overexpression led to a loss of epithelial traits and promoted aggressive cell behaviors.
  • Interestingly, ZEB1 overexpression was found to increase ZEB2 levels and vice versa, but ZEB2 exhibited greater potential for aggressive growth than ZEB1 in lab conditions.
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Addressing ageism in anesthesiology: valuing older physicians and enhancing their sense of belonging.

Can J Anaesth

October 2024

School of Medicine, Bowman Gray Center for Medical Education, Wake Forest University, 475 Vine Street, Winston-Salem, NC, 27101, USA.

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Cytotoxicity of bendamustine, alone and in combination with novel agents, toward adult T-cell leukemia cells.

PLoS One

September 2024

Division of Emerging Medicine for Integrated Therapeutics (EMIT), Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.

Article Synopsis
  • Bendamustine (BDM) has shown effectiveness in treating certain lymphomas with minimal side effects, but its impact on ATL had not been studied.
  • This research demonstrated that combining BDM with tucidinostat enhances cytotoxic effects and could potentially extend survival in patients with relapsed or refractory ATL, warranting further clinical investigation.
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Regional disparities in health literacy for chronic diseases: focusing on healthcare resources and local extinction index.

Front Public Health

September 2024

Department of Health Policy & Management, College of Public Health Science, Korea University, Seoul, Republic of Korea.

Objective: This study compared disparities between community health characteristics and health literacy levels for hypertension and diabetes by combining community-level characteristics, such as the local extinction index and healthcare resources, with individual-level characteristics based on the Andersen healthcare utilization model.

Method: Data obtained from the 2017, 2019, and 2021 Community Health Surveys, Korean Statistical Information Service, and National Health Insurance Service were analyzed. The analyses included spatial analysis, propensity score matching, and cross-analysis.

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