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Fluoropyrimidine-Associated Cardiotoxicity.
Cardiol Clin
November 2019
Cardio-Oncology Program, Division of Cardiovascular Medicine, CardioVascular Institute, Beth Israel Deaconess Medical Center, 3 Blackfan Circle, Center for Life Sciences Room 911, Boston, MA 02215, USA. Electronic address:
Article Synopsis
- Fluoropyrimidines are chemotherapy drugs effective against solid tumors, but their use can lead to serious heart-related side effects, known as cardiotoxicity.
- Symptoms of this cardiotoxicity can vary widely, including chest pain, heart attacks, and even sudden cardiac death.
- There are several proposed causes for these heart issues, such as blood vessel spasms and direct damage to heart tissue, and more research is needed to find effective preventive measures.