2 results match your criteria: "Center for Kidney Diseases Translational Medicine of Liaoning Province[Affiliation]"
The Profile of Timing Dialysis Initiation in Patients with End-stage Renal Disease in China: A Cohort Study.
Kidney Blood Press Res
November 2020
Department of Nephrology, Chinese PLA General Hospital, National Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Chinese PLA Institute of Nephrology, Beijing, China.
Background: Hemodialysis is the main approach for renal replacement therapy in patients with end-stage renal disease (ESRD) in China. The timing of dialysis initiation is one of the key factors influencing patient survival and prognosis. Over the past decade, the relationship between the timing of dialysis initiation and mortality has remained unclear in patients with ESRD in China.
View Article and Find Full Text PDFInhibition of core fucosylation limits progression of diabetic kidney disease.
Biochem Biophys Res Commun
December 2019
Graduate School of Dalian Medical University, 9 Western Section, Lvshun South Street, Lvshunkou District, Dalian, 116044, China; Department of Nephrology, The First Affiliated Hospital of Dalian Medical University, Center for Kidney Diseases Translational Medicine of Liaoning Province, Dalian, 116011, China. Electronic address:
Background: FUT8-mediated core fucosylation, which transfers a fucose residue from GDP-fucose to core-GlcNAc of the N-linked type glycoproteins, is crucial for signaling receptors function. Core fucosylation is involved in various biological processes such as cell proliferation, apoptosis, differentiation and immune regulation. Our previous studies demonstrated that inhibiting core fucosylation prevented renal interstitial fibrosis of UUO murine models, but its role in the development of diabetic kidney disease (DKD) remains unclear.
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