2 results match your criteria: "Center for Hereditary Tumours[Affiliation]"
Colorectal Dis
September 2023
Center for Hereditary Tumours, Evangelisches Bethesda Krankenhaus, Duisburg, Germany.
Tech Coloproctol
December 2004
Center for Hereditary Tumours, National Institute for Cancer Research, Genoa, Italy.
Familial adenomatous polyposis (FAP) is a rare genetic disease characterised by the development of hundreds to thousands of adenomatous polyps along the colon-rectum leading to cancer at a young age, if left untreated. In 1991, the gene responsible for the vast majority of FAP cases, the adenomatous polyposis coli (APC) gene, was identified. In 5-30% of FAP patients, no APC mutation is identifiable by current genetic testing.
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