322 results match your criteria: "Center for Health and Community[Affiliation]"

Children's executive functioning and health behaviors across pediatric life stages and ecological contexts.

J Behav Med

January 2025

Department of Counseling Psychology and Human Services, Prevention Science Institute, University of Oregon, Eugene, OR, USA.

Executive functioning (EF) has been linked to chronic disease risk in children. Health behaviors are thought to partially explain this association. The current cross-sectional study evaluated specific domains of EF and varied health behaviors in three pediatric life stages.

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Resource Realities: Exploring the Foundations of Successful Implementation in School-Based Drug Prevention.

J Sch Health

December 2024

Department of Veterans Affairs Quality Enhancement Research Initiative (QUERI), Department of Learning Health Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.

Background: Comprehensive health education in schools can effectively prevent drug use and related outcomes, but successful implementation remains challenging. Contextual determinants, including intervention-setting compatibility, focus on the intervention, available resources, and leadership support, influence implementation success. This study investigates the impact of multilevel contextual determinants on Michigan Model for Health: (MMH) curriculum fidelity.

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Effect of fetal apolipoprotein L1 genotype and vitamin D deficiencies on preeclampsia risk.

Pregnancy Hypertens

December 2024

Department of Genetics, Genomics, and Informatics, University of Tennessee Health Science Center, Memphis, TN, United States. Electronic address:

Background: Preeclampsia is a hypertensive disorder in pregnancy known to increase the risk of mortality and other pregnancy-related issues, such as prematurity. Currently, there no known prophylactics or treatment options available for preeclampsia. More research is needed to better understand factors that increase preeclampsia risk.

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Objectives: Few studies have analyzed potential inequities in both pediatric patient safety events (PSEs) and adverse events (AEs) - PSEs leading to harm - nor in PSEs by event type. We sought to examine potential inequities in rates of pediatric PSEs overall, by severity, and by category based on race and ethnicity, insurance payor, and language as measured using voluntary incident reports (IRs).

Methods: We conducted a retrospective cohort study of pediatric hospitalizations between January 19, 2012 through December 31, 2019 at a US urban, tertiary care children's hospital.

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Background: A systematic adaptation of an evidence-based state health curriculum (Michigan Model for Health™, MMH) was created to enhance physical activity and family engagement materials but retain the core functional elements of the curriculum.

Methods: The Framework for Reporting Adaptations and Modifications-Enhanced (FRAME) was used to document the adaptation, which used materials from an evidence-informed physical activity program (Interrupting Prolonged sitting with ACTivity, InPACT). Acceptability, appropriateness, feasibility, and perceived value of the adaptation were assessed by key stakeholders, regional school health coordinators (HCs).

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Associations Between Patient/Caregiver Trust in Clinicians and Experiences of Healthcare-Based Discrimination.

J Am Board Fam Med

October 2024

From the California University of Science and Medicine, Colton, CA (AK); Social Interventions Research and Evaluation Network, Center for Health and Community, University of California San Francisco, San Francisco, CA (LMG); Department of Family and Community Medicine, University of California San Francisco, San Francisco, CA (LMG, EHDM); Children's HealthWatch, Boston, MA (SEDC); School of Public Health & Chobanian and Avedisian School of Medicine, Boston University, Boston, MA (SEDC); Department of Medicine, University of Massachusetts Chan Medical School, North Worcester, MA (EB); Division of Emergency Medicine, Boston Children's Hospital, Boston, MA (EWF); Department of Pediatrics, Harvard Medical School, Boston, MA (EWF); Center of Innovation in Long Term Services and Supports, VA Providence Healthcare System, Providence, RI (AJC); Department of Family Medicine, Warren Alpert Medical School of Brown University (AJC); Department of Health Services, Policy, and Practice, Brown University School of Public Health (AJC); Section of General Internal Medicine, University of Chicago, Chicago, IL (NJG); Center for Community Health and Health Equity, Brigham and Women's Hospital, Boston, MA (MJO); Department of Medicine, Brigham and Women's Hospital, Boston, MA (CRC).

Background: Higher trust in healthcare providers has been linked to better health outcomes and satisfaction. Lower trust has been associated with healthcare-based discrimination.

Objective: Examine associations between experiences of healthcare discrimination and patients' and caregivers of pediatric patients' trust in providers, and identify factors associated with high trust, including prior experience of healthcare-based social screening.

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"We Need to Know These Things": Use Cases for Combined Social and Clinical Data Among Primary Care-Based Clinical and Social Care Providers.

J Prim Care Community Health

September 2024

Department of Family and Community Medicine and Social Interventions Research and Evaluation Network, Center for Health and Community, University of California San Francisco, San Francisco, CA, USA.

Introduction/objectives: Primary care organizations are increasingly collecting data on patients' social risks, bringing forth an unprecedented opportunity to present combined health and social data that clinical and social care providers could leverage to improve patient care and outcomes. Little is known, however, about how these data could be used and what combinations of specific data elements are most helpful. We explored how primary care staff who provide clinical or social care services view potential benefits of and use cases for combined patient-level clinical and social data.

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Parent-child border separation and the road to repair: addressing a global refugee phenomenon.

Attach Hum Dev

September 2024

Department of Psychiatry and Behavioral Sciences, Child Trauma Research Program, University of California, San Francisco, CA, USA.

As a result of the Department of Homeland Security's zero-tolerance policy (ZTP), over 5,000 children were separated from their parents at the U.S. southern border from 2017-2021, with over 1,000 still lacking confirmed reunifications.

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The researcher's guide to selecting biomarkers in mental health studies.

Bioessays

October 2024

Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Article Synopsis
  • Clinical mental health researchers often find it challenging to integrate biological assessments into their studies due to the complexity of the existing literature.
  • This paper offers guidelines to help researchers focus on biological pathways in their research, which can enhance understanding of mental health mechanisms and inform personalized treatment strategies.
  • The authors discuss the relevance and reliability of peripheral biomarkers, explore five types of biological tissues (blood, saliva, urine, stool, and hair), and offer strategies to manage measurement variability.
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Background: Although vaccines are largely effective and safe, there is variability in post-vaccination experience regarding antibody response, side effects, and affective outcomes. Vaccine mindsets, specific beliefs about the vaccine, may be associated with post-vaccination experience. This is important since mindsets are malleable and may help decrease vaccine hesitancy and improve post-vaccination experience.

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Introduction: The COVID-19 pandemic led to a dramatic increase in telemedicine use for direct patient care. Inequities in device/internet access can limit the extent to which patients can engage with telemedicine care and exacerbate health disparities. In this review, we examined existing literature on interventions designed to improve patient telemedicine access by providing digital devices including tablets, smartphones, and computers and/or internet connectivity.

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Grandparents' educational attainment is associated with grandchildren's epigenetic-based age acceleration in the National Growth and Health Study.

Soc Sci Med

August 2024

Center for Health and Community, School of Medicine, University of California, San Francisco, USA; Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California, San Francisco, USA. Electronic address:

Article Synopsis
  • The study investigated the impact of grandparents' educational levels on the epigenetic age acceleration of their grandchildren, considering the influence of parents' education and mothers' health factors.
  • Grandparents' education was linked to slower epigenetic aging, specifically through the Horvath age acceleration measure, indicating that grandchildren with educated grandparents showed healthier aging.
  • Results suggest that educational attainment in grandparents could have significant implications for the health of future generations, as it's tied to biological aging processes via mediating factors like parental education and mothers' cardiovascular health.
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Importance: Low childhood socioeconomic status (SES) is a social hallmark of aging that contributes to adult health disparities and earlier morbidity and mortality. Childhood perceptions of stress are associated with child health outcomes and may contribute to premature biological aging into adulthood.

Objective: To describe the association of childhood SES and perceived stress with midlife insulin resistance and epigenetic age and to explore whether late adolescent adiposity mediates the observed associations.

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Families' Perspectives on Social Services Navigation After Pediatric Urgent Care.

J Am Board Fam Med

August 2024

From the Department of Medicine, University of California, San Francisco (AA), Department of Neurology, University of California, Los Angeles (DEV), Social Interventions Research and Evaluation Network, Center for Health and Community, University of California, San Francisco (HW), Department of Family and Community Medicine, University of California, San Francisco (DH), Betty Irene Moore School of Nursing, University of California, Davis (VFK), School of Public Health, University of California, Berkeley (KSG); University of California, Berkeley-University of California, San Francisco, Joint Medical Program (KSG), Department of Family and Community Medicine and Social Interventions Research and Evaluation Network, Center for Health and Community, University of California, San Francisco (LMG).

Background: Interest is growing in clinic-based programs that screen for and intervene on patients' social risk factors, including housing, food, and transportation. Though several studies suggest these programs can positively impact health, few examine the mechanisms underlying these effects. This study explores pathways through which identifying and intervening on social risks can impact families' health.

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Background: Given its putative roles in mediating prosocial behavior, attachment bonds, and stress physiology, oxytocin modulation has been hypothesized to be a biological correlate of the salubrious effects of meditation practice. Here we investigated the effects of a month-long silent meditation retreat on changes in oxytocin, and the related hormone and vasopressin, in relation to psychosocial changes in attachment style, anxiety, personality measures, and feelings of social connectedness with fellow meditators.

Methods: Plasma oxytocin and vasopressin and self-report questionnaires were measured in retreat participants ( = 28) at the beginning of, and 3 weeks into, a residential meditation retreat.

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COVID-19 Vaccine Side Effects and Long-Term Neutralizing Antibody Response : A Prospective Cohort Study.

Ann Intern Med

July 2024

Department of Psychiatry and Behavioral Sciences, and Center for Health and Community, University of California, San Francisco, San Francisco, California (E.G.D., E.S.E., A.A.P.).

Background: Concern about side effects is a common reason for SARS-CoV-2 vaccine hesitancy.

Objective: To determine whether short-term side effects of SARS-CoV-2 messenger RNA (mRNA) vaccination are associated with subsequent neutralizing antibody (nAB) response.

Design: Prospective cohort study.

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Objectives: The main objectives of the current paper were to examine the feasibility, acceptability, and adherence of a remotely delivered intervention consisting of mindfulness-based stress reduction plus prenatal sleep classes (MBSR+PS) compared with treatment as usual (TAU).

Method: In this pilot randomized controlled trial, 52 pregnant women with poor sleep quality were randomized to MBSR+PS or TAU. MBSR was delivered through eight weekly 2.

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Introduction. During adolescence, individuals start to make autonomous decisions about their health. Vaccination involves contextual, group, and vaccine-specific dimensions.

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Objective: Workplace sugar-sweetened beverage (SSB) sales bans can reduce SSB consumption. Because stress and anxiety can promote sugar consumption, we examined whether anxiety among hospital employees during the COVID-19 pandemic was associated with changes in SSB consumption and explored whether this relationship varied by exposure to a workplace SSB sales ban.

Design: In a prospective, controlled trial of workplace SSB sales bans, we examined self-reported anxiety (generalised anxiety disorder-7) and self-reported SSB consumption (fluid ounces/d) before (July 2019) and during (May 2020) the COVID-19 pandemic.

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Dysregulation of the endocannabinoid (eCB) system is implicated in various stress-related neuropsychiatric disorders (SRDs), including anxiety, depression, and post-traumatic stress disorder (PTSD). In this systematic review and meta-analysis, our objectives were to characterize circulating anandamide (AEA) and 2-arachidonoylglycerol (2-AG) concentrations at rest and in response to acute laboratory-based psychosocial stress in individuals with SRDs and without (controls). Our primary aims were to assess the effects of acute psychosocial stress on eCB concentrations in controls (Aim 1), compare baseline (prestress) eCB concentrations between individuals with SRDs and controls (Aim 2), and explore differential eCB responses to acute psychosocial stress in individuals with SRDs compared with controls (Aim 3).

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Pediatric Research ECI highlight: Matthew S. Pantell.

Pediatr Res

May 2024

Division of Pediatric Hospital Medicine, Department of Pediatrics, University of California, San Francisco, CA, USA.

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Mindful eating is a promising strategy to address problematic eating behaviors; however, little is known about its applicability during pregnancy. No studies have examined the combined effects of mindful and practical eating skills on eating behaviors. We examined associations between mindful and practical eating skills and eating behaviors (nutritional intake and emotional eating) among pregnant women who received psychoeducation on healthy eating and pregnancies.

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Background: Research and clinical practice rely heavily on caregiver-report measures, such as the Child Behavior Checklist 1.5-5 (CBCL/1.5-5), to gather information about early childhood behavior problems and to screen for child psychopathology.

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Programming the next generation of prenatal programming of stress research: A review and suggestions for the future of the field.

Dev Psychopathol

December 2024

Department of Psychiatry and Behavioral Sciences, Center for Health and Community, Department of Pediatrics, Division of Developmental Medicine, University of California, San Francisco, CA, USA.

Article Synopsis
  • This article discusses how stress during pregnancy can affect a child’s brain development, mental health, and overall health outcomes, with a focus on various studies and reviews.
  • It highlights the contributions from different academic fields and outlines what has been learned so far, as well as the remaining challenges in the research.
  • The article also suggests future research directions, discusses ways to promote resilience and improve pregnancy interventions, and emphasizes the importance of applying research findings to practice and policy for better outcomes for both parents and children.
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