28 results match your criteria: "Center for Health Sciences Research[Affiliation]"

Article Synopsis
  • Proteomics is the extensive study of proteins, focusing on their structure and function through methods like identification and quantification.
  • The main approach, known as "shotgun" or "bottom-up proteomics," involves breaking proteins into smaller peptides for analysis via mass spectrometry.
  • This review aims to guide newcomers in proteomics by explaining various methods from basic biochemistry and protein extraction to interpretation and validation of results.
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Introduction: Hydrocephalus, altering cerebrospinal fluid (CSF) dynamics, affects 175 per 100,000 adults worldwide. Ventriculoperitoneal shunts (VPS) manage symptomatic hydrocephalus, with 125,000 cases annually. Despite efficacy, VPS face complications, necessitating interventions.

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Article Synopsis
  • Proteomics involves the large-scale study of proteins in biological systems, focusing on their identification and quantification through techniques like mass spectrometry.
  • * The predominant method used is "shotgun proteomics," where proteins are broken down into peptides for detailed analysis.
  • * This text aims to provide a comprehensive overview of various proteomics methods, from the basics of biochemistry to practical experimental strategies, serving as a resource for both novice and experienced researchers in the field.*
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Purpose: This study aimed to adapt a Spanish translation of the Oswestry Disability Index (ODI) into a cross-cultural version for the Mexican population. The objectives were to verify the validity and reliability of the adapted ODI and to compare pain perception between patients with and without obesity.

Material And Methods: We included 102 patients with low back pain from two neurosurgery departments in Mexico.

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Background & Aims: We utilized a triangulation method of a faculty development program's (FDP) evaluation comprising short-course workshops on classroom behaviors and lecturing skills of basic sciences faculty in a medical school.

Methods & Results: This study utilized data from the pre and post evaluation of classroom lectures by an expert observer. Course participants were observed before the inception of a 4-month FDP and after 6-months of program completion.

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Editorial: The Impact of Dietary Changes on Non-communicable Diseases in Latin America.

Front Nutr

March 2022

Center for Nutrition, Lifestyle, and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.

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Use of Medication for Opioid Use Disorder Among US Adolescents and Adults With Need for Opioid Treatment, 2019.

JAMA Netw Open

March 2022

Center for Health Sciences Research, Rutgers Institute for Health, Health Care Policy and Aging Research, New Brunswick, New Jersey.

Importance: Medication for opioid use disorder (MOUD) is the criterion standard treatment for opioid use disorder (OUD), but nationally representative studies of MOUD use in the US are lacking.

Objective: To estimate MOUD use rates and identify associations between MOUD and individual characteristics among people who may have needed treatment for OUD.

Design, Setting, And Participants: Cross-sectional, nationally representative study using the 2019 National Survey on Drug Use and Health in the US.

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Latin American countries show a fast-growing rate of non-communicable diseases (NCDs) and diet is a critical risk factor that must be properly assessed. Automated dietary assessment tools to collect 24-h dietary recalls (24HR) are lacking in Argentina. This study aimed to develop an open-access automated tool (MAR24) for collecting 24HR using a multiple pass method and a database containing foods and recipes commonly consumed in Argentina.

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This study aimed to evaluate changes in dietary and lifestyle habits during the period of confinement due to the first wave of the COVID-19 pandemic in Ibero-American countries. A cross-sectional investigation was conducted with 6,325 participants of both genders (68% women), over 18 years of age and from five countries: Brazil ( = 2,171), Argentina ( = 1,111), Peru ( = 1,174), Mexico ( = 686), and Spain ( = 1,183). Data were collected during the year 2020, between April 01 and June 30 in Spain and between July 13 and September 26, in the other countries studied using a self-administered online survey designed for the assessment of sociodemographic, employment, physical activity, health status, and dietary habits changes.

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An effective way to address risk factors for non-communicable chronic diseases (NCD) and reduce healthcare costs is by using sound health-related advice (HRA) to promote healthy lifestyle habits. In Argentina, however, few studies have examined the context in which HRA is communicated and undertaken by patients at the primary care level. In this study, we assessed the reception of HRA using a mixed-method approach in a central area of Argentina.

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Therapeutic strategies for Parkinson's disease: promising agents in early clinical development.

Expert Opin Investig Drugs

November 2020

Clinical Investigation Center CIC1436, Department of Clinical Pharmacology and Neurosciences, Parkinson Expert Centre and NeuroToul Center of Excellence in Neurodegeneration (COEN) of Toulouse; INSERM, University of Toulouse 3, CHU of Toulouse , Toulouse, France.

Introduction: To date, no drug has demonstrated clinically indisputable neuroprotective efficacy in Parkinson's disease (PD). We also have no effective symptomatic treatment for disabling symptoms such as balance problems, and dementia, and we need to improve the efficacy and safety profile of drugs currently used in the management of motor complications.

Areas Covered: We examine the agents which appear to have most therapeutic promise based on concepts, feasibility in a reasonable time frame, and available clinical data and place an emphasis on disease-modifying treatments.

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Background: The Hospital Survey on Patient Safety Culture (HSOPSC) is widely utilized in multiple languages across the world. Despite culture and language variations, research studies from Latin America use the Spanish language HSOPSC validated for Spain and the United States. Yet, these studies fail to report the translation method, cultural adaptation process, and the equivalence assessment strategy.

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Graduated nurses' experiences with baccalaureate thesis writing: A qualitative study.

Nurs Health Sci

September 2020

Research Nursing Group in Vulnerable Populations (GRIVIS-UAB), Nursing Department, Faculty of Medicine, Universitat Autónoma de Barcelona, Bellaterra, Spain.

This study explores the perceptions of newly graduated nurses regarding the baccalaureate thesis (BT) writing process. A qualitative approach with content analysis was adopted. Thirteen newly graduated nurses participated in the study.

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Exploration of clients living with HIV needs for reporting on experiences with sex.

Nurs Health Sci

September 2020

Grupo de Investigación Enfermera en Vulnerabilidad y Salud (GRIVIS), Nursing Department, Faculty of Medicine, Universitat Autonoma de Barcelona, Spain.

Talking about sex with people living with HIV receives insufficient attention in health care. A cross-sectional and exploratory study describes the preferences of people living with HIV to talk about sex with specialized HIV physicians and nurses in a clinic in Barcelona (Spain). A 27-item self-administered questionnaire was used between June 2017 and May 2018.

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Background: There are approximately 72,000 people living with HIV/AIDS (PLHIV) in Peru. Non-adherence to antiretroviral therapy (ART) is the most important factor for therapeutic failure and the development of resistance. Peru has achieved moderate progress in meeting the 90-90-90 targets, but only 60% of PLHIV receiving ART are virally suppressed.

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Healthy Vegan Lifestyle Habits among Argentinian Vegetarians and Non-Vegetarians.

Nutrients

January 2019

Center for Health Sciences Research, School of Medicine and Health Sciences, Universidad Adventista del Plata, Libertador San Martín, 25 de Mayo 99, Entre Ríos 3103, Argentina.

Article Synopsis
  • Research on healthy vegan diets in South America, specifically Argentina, is limited, prompting a study on adherence to vegan lifestyle habits among different dietary groups.
  • The study involved 1,454 participants, mainly females and young adults, and revealed that vegans scored highest on adherence to healthy habits, followed by various vegetarian groups and non-vegetarians.
  • Vegans spent a lower proportion of their household income on food but overall, the population showed low consumption of essential whole foods, indicating a need to enhance healthy eating and lifestyle to reduce non-communicable disease risks in Argentina.
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Effect of Velocity-Based Loading on Acceleration Kinetics and Kinematics During Sled Towing.

J Strength Cond Res

April 2021

Center for Applied Sport, Exercise and Nutritional Sciences, School of Sport and Wellbeing, Faculty of Health and Wellbeing, University of Central Lancashire, Preston, United Kingdom.

Bentley, I, Sinclair, JK, Atkins, SJ, Metcalfe, J, and Edmundson, CJ. Effect of velocity-based loading on acceleration kinetics and kinematics during sled towing. J Strength Cond Res 35(4): 1030-1038, 2021-Sled towing (ST) provides an external load in the form of a sled towed using a shoulder or waist harness and cord behind the athlete.

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Chia seeds () provide an unusually high content of α-linolenic acid with several potential health benefits, but few studies have examined the long-term intake of -3 fatty acid-rich plant foods such as chia. In this work, we investigated some of the effects of a diet containing 10% chia seeds versus a conventional isocaloric diet for 10 and 13 months on body measurements, musculoskeletal system, the liver, and the intestines of 20 male Sprague-Dawley rats assigned into two groups. The -6/-3 ratios for the control and chia diets were 7.

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Introduction: Sepsis is a major public health problem, frequent, costly, and often fatal. Despite of improvements in supportive treatments the incidence of sepsis and the number of deaths related to sepsis is increasing. Statins have been recently proposed as adjuvants in the treatment of sepsis, but its effects on mortality show conflicting results worldwide.

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Risk Factors for Chronic Diseases and Multimorbidity in a Primary Care Context of Central Argentina: A Web-Based Interactive and Cross-Sectional Study.

Int J Environ Res Public Health

March 2017

Center for Health Sciences Research, School of Medicine & Health Sciences, Universidad Adventista del Plata, Libertador San Martín, 25 de Mayo 99, Entre Ríos 3103, Argentina.

Global health agencies estimate an increase of chronic diseases in South America. Nevertheless, few studies have investigated chronic diseases and their risk factors in the perspective of multimorbidity. This research aimed to identify these aspects in a primary health care setting of central Argentina.

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Background: In lupus nephritis (LN), deposition of pathogenic autoantibodies in the glomeruli is mediated via cross-reactivity with alpha-actinin. Association of serum alpha-actinin antibody (AαA) with LN has been shown in a few studies but the results are controversial.

Methods: Eighty patients into entered the study.

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Cancer is the second most important non-communicable disease worldwide and disproportionately impacts low- to middle-income countries. Diet in combination with other lifestyle habits seems to modify the risk for some cancers but little is known about South Americans. Food habits of Argentinean men pre- and post-diagnosis of prostate cancer (n = 326) were assessed along with other lifestyle factors.

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Locus of control as a moderator of the relationship between medication barriers (e.g., side-effects, forgetting to take medication, and keeping track of pills) and anti-hypertensive medication adherence was examined.

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Physical therapy use by community-based older people.

Phys Ther

January 2005

Cecil G Sheps Center for Health Sciences Research, University of North Carolina, Chapel Hill, NC 27599, USA.

Background And Purpose: Little information is available on factors associated with physical therapy use. Identifying the characteristics of people who use physical therapy and some of the factors associated with its use is a useful first step in determining whether disparities exist in physical therapy use. The purpose of this study was to identify factors associated with physical therapy use by community-based older people.

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