1 results match your criteria: "Center for Gender in Medicine and Cardiovascular Research Center[Affiliation]"
Altered melusin expression in the hearts of aortic stenosis patients.
Eur J Heart Fail
August 2007
Center for Gender in Medicine and Cardiovascular Research Center, Charité Berlin, Germany.
Background: The role of melusin, a necessary component in pressure-induced left-ventricular hypertrophy (LVH) in mice, has not yet been determined in human cardiac hypertrophy. We analyzed for the first time the expression and regional distribution of melusin in human LVH due to aortic stenosis (AS) and determined AKT phosphorylation as a potential downstream effector of melusin signalling.
Methods: Regional distribution of melusin was evaluated in four normal hearts.