2 results match your criteria: "Center for Emerging Zoonotic and Arthropod-borne Diseases[Affiliation]"
GABA-gated chloride channel mutation (Rdl) induces cholinergic physiological compensation resulting in cross resistance in Drosophila melanogaster.
Pestic Biochem Physiol
August 2024
Virginia Polytechnic Institute and State University, Department of Entomology, Molecular Physiology and Toxicology Laboratory Blacksburg, VA 24061, USA; School of Neuroscience, Fralin Life Science Institute, Virginia Tech Center for Drug Discovery, Center for Emerging Zoonotic and Arthropod-borne Diseases, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address:
The Drosophila melanogaster MD-RR strain contains an Rdl mutation (A301S) resulting in resistance to several insecticide classes viz. phenyl pyrazoles (e.g.
View Article and Find Full Text PDFMuscarinic acetylcholine receptor activation synergizes the knockdown and toxicity of GABA-gated chloride channel insecticides.
Pest Manag Sci
November 2022
Molecular Physiology and Toxicology Laboratory, Department of Entomology, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.
Background: Pest management requires continual identification of new physiological targets and strategies to control pests affecting agriculture and public/animal health. We propose the muscarinic system as a target for agrochemicals because of its physiological importance. Unlike the muscarinic system, gamma-amino butyric acid (GABA) receptors are an established insecticide target.
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