Does postoperative low-dose duloxetine provide analgesic effect and lower morphine consumption after primary total knee arthroplasty? A prospective, double-blind, randomized controlled trial.

Introduction: Duloxetine as an adjunct analgesic has shown effective results in trials of patients undergoing total knee arthroplasty (TKA). However, the regimen has not been standardized. We, therefore, evaluated the analgesic efficacy of low-dose duloxetine after TKA.

Comparative effectiveness of combined peri-articular and intra-articular injection versus intravenous and intra-articular injection of tranexamic acid in total knee arthroplasty: a randomized controlled trial study.

Introduction: Tranexamic acid (TXA) administration is supported by numerous evidence in reducing blood loss after total knee arthroplasty (TKA). The combination of intravenous (IV) and intra-articular (IA) TXA administration revealed good result in blood loss reduction with less evidence of venous thromboembolism event (VTE). Several literature reviews portray that peri-articular (PA) administration yields similar hemostasis in comparison to IV route.

Decision-making deficits in obsessive-compulsive disorder are associated with abnormality of recency and response consistency parameter in prospect valence learning model.

Background: Patients with obsessive-compulsive disorder (OCD) have deficits in decision-making in the Iowa Gambling Task (IGT). However, no study has investigated the parameters of the prospect valence learning (PVL) model in the IGT for OCD.

Aims: This study aimed to investigate deficits in decision-making in OCD using the PVL model and identify whether the parameters of the PVL model were associated with obsessive-compulsive severity.

Laser cooling with intermediate state of spin-orbit coupling of LuF molecule.

This work presents a theoretical study of the laser cooling feasibility of the molecule LuF, in the fine structure level of approximation. An ab-initio complete active space self-consistent field (CASSCF)/MRCI with Davidson correction calculation has been done in the Λ and Ω representations. The corresponding adiabatic potential energy curves and spectroscopic parameters have been investigated for the low-lying electronic states.

The Comparative Effects of Teacher Versus Peer-Scaffolding on EFL Learners' Incidental Vocabulary Learning and Reading Comprehension: A Socio-Cultural Perspective.

Drawing on sociocultural theory, and multiple empirical studies conducted on the effectiveness of scaffolding on second or foreign language learning, the authors investigated the application of various forms of scaffolding (i.e., teacher versus peer-scaffolding) on EFL learners' incidental vocabulary learning and reading comprehension performance through a sociocultural perspective.

Effect of coronary artery bypass grafting on blood pressure response to head-up tilting.

Blood pressure response to head-up tilt (HUT) in 7 healthy subjects and 9 patients before and after coronary artery bypass grafting (CABG) was measured during supine and 15-min 60° HUT. Stroke volume (SV) and ejection fraction (EF) were assessed by echocardiography. Baseline mean arterial pressure (MAP) and heart rate (HR) in patients before CABG were similar to healthy subjects.

Myositis with sarcoplasmic inclusions in Nakajo-Nishimura syndrome: a genetic inflammatory myopathy.

Aims: Nakajo-Nishimura syndrome (NNS) is an autosomal recessive disease caused by biallelic mutations in the PSMB8 gene that encodes the immunoproteasome subunit β5i. There have been only a limited number of reports on the clinicopathological features of the disease in genetically confirmed cases.

Methods: We studied clinical and pathological features of three NNS patients who all carry the homozygous p.

The Effect of Medical Recording Training on Quantity and Quality of Recording in Gynecology Residents of Tabriz University of Medical Sciences.

Medical records contain valuable information about a patient's medical history and treatment. Patient safety is one of the most important dimensions of health care quality assurance and performance improvement. Completing the process of documentation is necessary to continue patient care and continuous quality improvement of basic services.

Cardiovascular responses to microinjections of endomorphin-2 into the nucleus of the solitary tract are attenuated in the spontaneously hypertensive rat.

Stimulation of µ1-opioid receptors (M1ORs) in the medial nucleus solitarius (mNTS) by endomorphin-2 (EM2) elicits decreases in mean arterial pressure (MAP), heart rate (HR) and greater splanchnic nerve activity (GSNA) in Wistar rats. We tested the hypothesis that EM2-induced responses in the mNTS may be attenuated in the spontaneously hypertensive rat (SHR). Experiments were carried out in urethane-anesthetized, artificially ventilated, adult male SHR and Wistar-Kyoto rats (WKY).

The social psychology of disintegrative shaming in education.

Despite considerable research concerning drug education and zero tolerance policies, few have examined their combined youth impact. Comprehensive and nationally recognized mixed method evidence is drawn from 77 school districts and 118 schools in the Drug, Alcohol and Tobacco Education (DATE) evaluation. For the first time it is found that the combined negative impact of traditional prevention and intervention efforts--e.

Resilience and risk competence in schools: theory/knowledge and international application in project rebound.

Despite a 50-year interdisciplinary and longitudinal research legacy--showing that nearly 80% of young people considered most "at risk" thrive by midlife-only recently have practitioners/researchers engaged in the explicit, prospective facilitation of "resilience" in educational settings. Here, theory/knowledge distinguishing and extending risk and resilience from its risk-based social history to resilience's normative occurrence leads to the first known international and prospective application of resilience in school-based drug education, Project REBOUND [resilience-bound]. It will be implemented as a controlled pilot study, first in Germany, then expand to the United States, as well as other parts of Europe.

Surfacing Filipino student nurses' perspectives of comfort and comforting viewed through metaphorical lens.

Background: Comfort has been an integral component of nursing interventions. It is also supposed that the degree to which comfort is evidenced in nursing performance depends in great measure on the way forthcoming nurses perceive the said construct during their educational training.

Objective: This study purports to describe student nurses' outlook of the words "comfort" and "comforting", through conscious doodling, and at the same time to find out instances of similarity or striking distinctions in students' perception on the said terms.

Youth, drugs and resilience education.

Billions of dollars are spent annually on school-based drug education programs, with youthful drug use remaining near peak levels since the 1980s. Institutional, policy, and program evidence presented here suggests that although primarily delivered in schools, the educational community rarely participates in the development of drug education; and despite the finding that "no-use" programs such as Drug Abuse Resistance Education (D.A.